Matches in SemOpenAlex for { <https://semopenalex.org/work/W4308247412> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W4308247412 endingPage "e2022207" @default.
- W4308247412 startingPage "e2022207" @default.
- W4308247412 abstract "Background： Patients with multifocal superficial basal cell carcinomas (sBCC) require a non-invasive treatment and follow-up with a non-invasive technique. Imiquimod 5% cream is a new non-invasive therapy for BCC. Reflectance confocal microscopy (RCM) is a non-invasive, real-time imaging technique.
 Methods：The efficacy of imiquimod 5% cream for the treatment of multifocal sBCC was evaluated, as well as the potential of RCM for assessing therapeutic effects. We reported four patients with 34 sBCC lesions were treated with imiquimod 5% cream. RCM was performed in the baseline and at 12 weeks, 24 weeks and 52 weeks after starting treatment.
 Results： Of 34 lesions treated with imiquimod 5%, 32 responded to the treatment and showed complete clinical clearing. Two subclinical BCC lesions were identified by RCM. The complete tumor clearance rate was 88.2%, and the efficiency rate was 97.1%. No lesion recurred at 24-month follow-up. RCM identified previously described confocal features of BCC and was more sensitive than clinical examination. Local skin reactions were relieved after expectant treatment.
 Conclusions： Imiquimod 5% cream may be useful for the treatment of multifocal sBCC, and its side effects are easy to manage. RCM can be used for non-invasive monitoring of treatment response and improved the tumor clearance rate.
" @default.
- W4308247412 created "2022-11-09" @default.
- W4308247412 creator A5013205197 @default.
- W4308247412 creator A5039282511 @default.
- W4308247412 creator A5058714794 @default.
- W4308247412 date "2022-10-31" @default.
- W4308247412 modified "2023-10-14" @default.
- W4308247412 title "Reflectance confocal microscopy follow-up of multifocal superficial basal cell carcinomas treated with imiquimod 5% cream" @default.
- W4308247412 cites W1975300769 @default.
- W4308247412 cites W1995901066 @default.
- W4308247412 cites W2000743922 @default.
- W4308247412 cites W2006936784 @default.
- W4308247412 cites W2048792089 @default.
- W4308247412 cites W2049607284 @default.
- W4308247412 cites W2054947389 @default.
- W4308247412 cites W2070611587 @default.
- W4308247412 cites W2122817540 @default.
- W4308247412 cites W2140595519 @default.
- W4308247412 cites W2545089004 @default.
- W4308247412 cites W2761067032 @default.
- W4308247412 cites W2767005502 @default.
- W4308247412 cites W2899682518 @default.
- W4308247412 cites W2900492842 @default.
- W4308247412 cites W2931221067 @default.
- W4308247412 cites W177407420 @default.
- W4308247412 doi "https://doi.org/10.5826/dpc.1204a207" @default.
- W4308247412 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36534551" @default.
- W4308247412 hasPublicationYear "2022" @default.
- W4308247412 type Work @default.
- W4308247412 citedByCount "0" @default.
- W4308247412 crossrefType "journal-article" @default.
- W4308247412 hasAuthorship W4308247412A5013205197 @default.
- W4308247412 hasAuthorship W4308247412A5039282511 @default.
- W4308247412 hasAuthorship W4308247412A5058714794 @default.
- W4308247412 hasBestOaLocation W43082474121 @default.
- W4308247412 hasConcept C113280763 @default.
- W4308247412 hasConcept C142724271 @default.
- W4308247412 hasConcept C16005928 @default.
- W4308247412 hasConcept C2777873816 @default.
- W4308247412 hasConcept C2779112978 @default.
- W4308247412 hasConcept C2779178360 @default.
- W4308247412 hasConcept C2781156865 @default.
- W4308247412 hasConcept C3019992690 @default.
- W4308247412 hasConcept C71924100 @default.
- W4308247412 hasConcept C86803240 @default.
- W4308247412 hasConcept C95444343 @default.
- W4308247412 hasConceptScore W4308247412C113280763 @default.
- W4308247412 hasConceptScore W4308247412C142724271 @default.
- W4308247412 hasConceptScore W4308247412C16005928 @default.
- W4308247412 hasConceptScore W4308247412C2777873816 @default.
- W4308247412 hasConceptScore W4308247412C2779112978 @default.
- W4308247412 hasConceptScore W4308247412C2779178360 @default.
- W4308247412 hasConceptScore W4308247412C2781156865 @default.
- W4308247412 hasConceptScore W4308247412C3019992690 @default.
- W4308247412 hasConceptScore W4308247412C71924100 @default.
- W4308247412 hasConceptScore W4308247412C86803240 @default.
- W4308247412 hasConceptScore W4308247412C95444343 @default.
- W4308247412 hasLocation W43082474121 @default.
- W4308247412 hasLocation W43082474122 @default.
- W4308247412 hasLocation W43082474123 @default.
- W4308247412 hasOpenAccess W4308247412 @default.
- W4308247412 hasPrimaryLocation W43082474121 @default.
- W4308247412 hasRelatedWork W1984700728 @default.
- W4308247412 hasRelatedWork W2011931448 @default.
- W4308247412 hasRelatedWork W2012464070 @default.
- W4308247412 hasRelatedWork W2032311016 @default.
- W4308247412 hasRelatedWork W2046703086 @default.
- W4308247412 hasRelatedWork W2304381409 @default.
- W4308247412 hasRelatedWork W2410162921 @default.
- W4308247412 hasRelatedWork W2417509913 @default.
- W4308247412 hasRelatedWork W3021885120 @default.
- W4308247412 hasRelatedWork W4386021900 @default.
- W4308247412 isParatext "false" @default.
- W4308247412 isRetracted "false" @default.
- W4308247412 workType "article" @default.