Matches in SemOpenAlex for { <https://semopenalex.org/work/W4308271409> ?p ?o ?g. }
- W4308271409 endingPage "202" @default.
- W4308271409 startingPage "182" @default.
- W4308271409 abstract "Colorectal cancer (CRC) is an abnormal growth that occurs in the rectum or rectal portion. In 2020, an anticipated 104,610 new cases of colon illness and 43,340 new cases of rectal abnormal growth were expected in the United States. Red and processed meat, body bloatedness, belly fatness, and binge drinking expands the occurrence of colorectal disease. Dietary fibres contribute to faecal bulking, but they are break down by gut bacteria and produce metabolites such as short-chain fatty acids (SCFAs). SCFAs are chemical compounds that are mostly made up of acetate, propionate, and butyrate. Acetate and butyrate help to control mucus production and discharge, and thus, protect the gut mucosa. Reduced mucus secretion/increased bacterial catabolism, and fermentation of amino acids resulted in an increase of potentially detrimental metabolites such as branched-chain fatty acids, ammonia, amines, and N-nitroso complex components. Vital roles of fibres include reduction in the time that carcinogens encounter the intestinal lumen and promotion of healthy gut microbiota as well as modification of the host metabolism. The present review focuses on a brief introduction to various dietary fibres and specialised metabolites that can possess beneficial effect on CRC, as well as presenting our current, detailed understanding of various dietary fibres along with their potential effects on gut microbiota and its association with the colon cancer. A comprehensive discussion is also included, advocating the dietary fibre-enriched diet." @default.
- W4308271409 created "2022-11-10" @default.
- W4308271409 creator A5011769386 @default.
- W4308271409 creator A5012357296 @default.
- W4308271409 creator A5016129380 @default.
- W4308271409 creator A5056035453 @default.
- W4308271409 creator A5057487835 @default.
- W4308271409 creator A5060027507 @default.
- W4308271409 creator A5063731295 @default.
- W4308271409 date "2022-11-02" @default.
- W4308271409 modified "2023-09-25" @default.
- W4308271409 title "A Mechanistic Overview on Impact of Dietary Fibres on Gut Microbiota and Its Association with Colon Cancer" @default.
- W4308271409 cites W1612925887 @default.
- W4308271409 cites W1741548448 @default.
- W4308271409 cites W1945596138 @default.
- W4308271409 cites W1968105193 @default.
- W4308271409 cites W1972969865 @default.
- W4308271409 cites W1973265172 @default.
- W4308271409 cites W1974088543 @default.
- W4308271409 cites W1980383179 @default.
- W4308271409 cites W1981504305 @default.
- W4308271409 cites W1982013562 @default.
- W4308271409 cites W2000836424 @default.
- W4308271409 cites W2002208004 @default.
- W4308271409 cites W2003138081 @default.
- W4308271409 cites W2003753078 @default.
- W4308271409 cites W2003984982 @default.
- W4308271409 cites W2005839559 @default.
- W4308271409 cites W2012800693 @default.
- W4308271409 cites W2016435923 @default.
- W4308271409 cites W2023678020 @default.
- W4308271409 cites W2030373321 @default.
- W4308271409 cites W2032230795 @default.
- W4308271409 cites W2035421462 @default.
- W4308271409 cites W2039455082 @default.
- W4308271409 cites W2046743796 @default.
- W4308271409 cites W2054338737 @default.
- W4308271409 cites W2057574272 @default.
- W4308271409 cites W2058801524 @default.
- W4308271409 cites W2060185417 @default.
- W4308271409 cites W2061678430 @default.
- W4308271409 cites W2066439912 @default.
- W4308271409 cites W2082808164 @default.
- W4308271409 cites W2085175109 @default.
- W4308271409 cites W2086959952 @default.
- W4308271409 cites W2087278385 @default.
- W4308271409 cites W2087292184 @default.
- W4308271409 cites W2087966568 @default.
- W4308271409 cites W2089177264 @default.
- W4308271409 cites W2095040140 @default.
- W4308271409 cites W2095416491 @default.
- W4308271409 cites W2097936419 @default.
- W4308271409 cites W2098944337 @default.
- W4308271409 cites W2101238009 @default.
- W4308271409 cites W2101911260 @default.
- W4308271409 cites W2104423086 @default.
- W4308271409 cites W2107414352 @default.
- W4308271409 cites W2109569804 @default.
- W4308271409 cites W2110936821 @default.
- W4308271409 cites W2114866762 @default.
- W4308271409 cites W2117881676 @default.
- W4308271409 cites W2119546263 @default.
- W4308271409 cites W2121430417 @default.
- W4308271409 cites W2124557952 @default.
- W4308271409 cites W2127743008 @default.
- W4308271409 cites W2127906539 @default.
- W4308271409 cites W2134176478 @default.
- W4308271409 cites W2137090067 @default.
- W4308271409 cites W2140914621 @default.
- W4308271409 cites W2144494558 @default.
- W4308271409 cites W2144662796 @default.
- W4308271409 cites W2145159460 @default.
- W4308271409 cites W2146167376 @default.
- W4308271409 cites W2147169580 @default.
- W4308271409 cites W2148530063 @default.
- W4308271409 cites W2149074973 @default.
- W4308271409 cites W2150569822 @default.
- W4308271409 cites W2151845029 @default.
- W4308271409 cites W2152575922 @default.
- W4308271409 cites W2153374978 @default.
- W4308271409 cites W2153394357 @default.
- W4308271409 cites W2154114392 @default.
- W4308271409 cites W2156962544 @default.
- W4308271409 cites W2161776662 @default.
- W4308271409 cites W2163878401 @default.
- W4308271409 cites W2165820853 @default.
- W4308271409 cites W2166562121 @default.
- W4308271409 cites W2171225262 @default.
- W4308271409 cites W2178038387 @default.
- W4308271409 cites W2236332835 @default.
- W4308271409 cites W2274927794 @default.
- W4308271409 cites W2287246374 @default.
- W4308271409 cites W2344885638 @default.
- W4308271409 cites W2402506709 @default.
- W4308271409 cites W2409656339 @default.
- W4308271409 cites W2418984266 @default.
- W4308271409 cites W2461078957 @default.
- W4308271409 cites W2527872371 @default.