FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4308271729> ?p ?o ?g. }

• W4308271729 abstract "Abstract Anorexia nervosa (AN) is a severe and complex psychiatric disorder with the highest mortality rate of all psychiatric disorders. Previous observational studies indicated inconclusive association between inflammatory bowel disease (IBD) and AN, and the causal effect remains unclear. We aimed to test the hypothesis that a causal relationship exists between IBD and the risk of AN using the Mendelian randomization (MR) analysis. The inverse-variance weighted (IVW) method was employed as the primary analysis. Furthermore, various sensitivity analyses were conducted to assess the robustness of our results. Notably, IVW analysis of univariable MR revealed that genetically predicted IBD were significantly casually associated with AN risk (N SNP = 12, odds ratio [OR]: 1.143, 95% confidence interval [CI]: 1.032–1.266, P = 0.01). In subgroups, consistent positive causal associations with AN might show in ulcerative colitis (UC) (N SNP = 6, OR: 1.153, 95% CI: 1.022–1.301, P = 0.021), and Crohn's disease (CD) (N SNP = 4, OR: 1.153, 95% CI: 1.008–1.319, P = 0.037). Besides, there was no heterogeneity and horizontal pleiotropy observed in the sensitivity analysis. Our study identifies that patients diagnosed with IBD, including UC and CD, could be causally associated with an increased risk of AN. It may have clinical benefits for early detection of AN and clinical decisions on management of IBD patients." @default.
• W4308271729 created "2022-11-10" @default.
• W4308271729 creator A5007710148 @default.
• W4308271729 creator A5008556107 @default.
• W4308271729 creator A5022499603 @default.
• W4308271729 creator A5023539148 @default.
• W4308271729 creator A5024733849 @default.
• W4308271729 creator A5030880030 @default.
• W4308271729 creator A5035519623 @default.
• W4308271729 creator A5048926985 @default.
• W4308271729 creator A5051746576 @default.
• W4308271729 creator A5053755016 @default.
• W4308271729 creator A5057973097 @default.
• W4308271729 date "2022-11-04" @default.
• W4308271729 modified "2023-10-18" @default.
• W4308271729 title "Causal Association of Inflammatory Bowel Disease on Anorexia Nervosa: A Two-sample Mendelian Randomization Study" @default.
• W4308271729 cites W1886554201 @default.
• W4308271729 cites W1976796596 @default.
• W4308271729 cites W2070139228 @default.
• W4308271729 cites W2093980670 @default.
• W4308271729 cites W2123349506 @default.
• W4308271729 cites W2155309026 @default.
• W4308271729 cites W2460883514 @default.
• W4308271729 cites W2470875017 @default.
• W4308271729 cites W2550505191 @default.
• W4308271729 cites W2597850678 @default.
• W4308271729 cites W2613022045 @default.
• W4308271729 cites W2613603864 @default.
• W4308271729 cites W2687532560 @default.
• W4308271729 cites W2754281754 @default.
• W4308271729 cites W2766325219 @default.
• W4308271729 cites W2890904296 @default.
• W4308271729 cites W2911642049 @default.
• W4308271729 cites W2926911490 @default.
• W4308271729 cites W2943085208 @default.
• W4308271729 cites W2995517477 @default.
• W4308271729 cites W3001022613 @default.
• W4308271729 cites W3199355847 @default.
• W4308271729 cites W3204254150 @default.
• W4308271729 cites W4220918033 @default.
• W4308271729 cites W4220966186 @default.
• W4308271729 cites W4255815262 @default.
• W4308271729 doi "https://doi.org/10.21203/rs.3.rs-2198843/v1" @default.
• W4308271729 hasPublicationYear "2022" @default.
• W4308271729 type Work @default.
• W4308271729 citedByCount "0" @default.
• W4308271729 crossrefType "posted-content" @default.
• W4308271729 hasAuthorship W4308271729A5007710148 @default.
• W4308271729 hasAuthorship W4308271729A5008556107 @default.
• W4308271729 hasAuthorship W4308271729A5022499603 @default.
• W4308271729 hasAuthorship W4308271729A5023539148 @default.
• W4308271729 hasAuthorship W4308271729A5024733849 @default.
• W4308271729 hasAuthorship W4308271729A5030880030 @default.
• W4308271729 hasAuthorship W4308271729A5035519623 @default.
• W4308271729 hasAuthorship W4308271729A5048926985 @default.
• W4308271729 hasAuthorship W4308271729A5051746576 @default.
• W4308271729 hasAuthorship W4308271729A5053755016 @default.
• W4308271729 hasAuthorship W4308271729A5057973097 @default.
• W4308271729 hasBestOaLocation W43082717291 @default.
• W4308271729 hasConcept C104317684 @default.
• W4308271729 hasConcept C126322002 @default.
• W4308271729 hasConcept C135763542 @default.
• W4308271729 hasConcept C156957248 @default.
• W4308271729 hasConcept C2778260677 @default.
• W4308271729 hasConcept C2779134260 @default.
• W4308271729 hasConcept C2779901538 @default.
• W4308271729 hasConcept C2780479503 @default.
• W4308271729 hasConcept C2993967602 @default.
• W4308271729 hasConcept C44249647 @default.
• W4308271729 hasConcept C54355233 @default.
• W4308271729 hasConcept C71924100 @default.
• W4308271729 hasConcept C86803240 @default.
• W4308271729 hasConcept C90924648 @default.
• W4308271729 hasConceptScore W4308271729C104317684 @default.
• W4308271729 hasConceptScore W4308271729C126322002 @default.
• W4308271729 hasConceptScore W4308271729C135763542 @default.
• W4308271729 hasConceptScore W4308271729C156957248 @default.
• W4308271729 hasConceptScore W4308271729C2778260677 @default.
• W4308271729 hasConceptScore W4308271729C2779134260 @default.
• W4308271729 hasConceptScore W4308271729C2779901538 @default.
• W4308271729 hasConceptScore W4308271729C2780479503 @default.
• W4308271729 hasConceptScore W4308271729C2993967602 @default.
• W4308271729 hasConceptScore W4308271729C44249647 @default.
• W4308271729 hasConceptScore W4308271729C54355233 @default.
• W4308271729 hasConceptScore W4308271729C71924100 @default.
• W4308271729 hasConceptScore W4308271729C86803240 @default.
• W4308271729 hasConceptScore W4308271729C90924648 @default.
• W4308271729 hasLocation W43082717291 @default.
• W4308271729 hasLocation W43082717292 @default.
• W4308271729 hasOpenAccess W4308271729 @default.
• W4308271729 hasPrimaryLocation W43082717291 @default.
• W4308271729 hasRelatedWork W2050280907 @default.
• W4308271729 hasRelatedWork W2070285775 @default.
• W4308271729 hasRelatedWork W2124908533 @default.
• W4308271729 hasRelatedWork W2258300052 @default.
• W4308271729 hasRelatedWork W2408939568 @default.
• W4308271729 hasRelatedWork W2418837291 @default.
• W4308271729 hasRelatedWork W2512626908 @default.
• W4308271729 hasRelatedWork W2765379856 @default.
• W4308271729 hasRelatedWork W46359855 @default.

• next