Matches in SemOpenAlex for { <https://semopenalex.org/work/W4308308199> ?p ?o ?g. }
- W4308308199 endingPage "105284" @default.
- W4308308199 startingPage "105284" @default.
- W4308308199 abstract "In insects, cytochrome P450 monooxygenases (P450s or CYPs) play an important role in the detoxification and metabolism of exogenous plant allelochemicals. In this study, a P450 gene CYP6AB12 was identified and characterized from Spodoptera litura. The cDNA contains an open reading frame (ORF) encoding 511 amino acid residues. CYP6AB12 was expressed at different ages of S. litura, with the highest levels found in the third and fourth instar larvae. Its highest expression was found in the midgut and fat body of fourth instar larvae fed with gossypol. Moreover, these expression levels were substantially increased compared with those from larvae fed with control diet. Gene silencing was then conducted by smearing dsRNA mixed with nanomaterials onto the cuticle. CYP6AB12 expression was significantly decreased in the midgut and fat body, and the net weight increase was substantially lower than that of the control group, indicating that the treatment group had more sensitivity to gossypol than the control. These results reveal that CYP6AB12 plays an important role in the detoxification and metabolism of gossypol, thus further confirming that P450s have a broad ability to detoxify and metabolize plant allelochemicals. It provides an important molecular basis for the exploration of detoxification metabolism and pest control of S. litura." @default.
- W4308308199 created "2022-11-10" @default.
- W4308308199 creator A5003448004 @default.
- W4308308199 creator A5012278873 @default.
- W4308308199 creator A5023409516 @default.
- W4308308199 creator A5033172297 @default.
- W4308308199 creator A5040922074 @default.
- W4308308199 creator A5052342339 @default.
- W4308308199 creator A5062534699 @default.
- W4308308199 creator A5064072874 @default.
- W4308308199 creator A5070921750 @default.
- W4308308199 creator A5085822810 @default.
- W4308308199 creator A5089026355 @default.
- W4308308199 date "2022-11-01" @default.
- W4308308199 modified "2023-10-17" @default.
- W4308308199 title "Knockdown of cytochrome P450 gene CYP6AB12 based on nanomaterial technology reduces the detoxification ability of Spodoptera litura to gossypol" @default.
- W4308308199 cites W1557506896 @default.
- W4308308199 cites W1964204250 @default.
- W4308308199 cites W1986812875 @default.
- W4308308199 cites W2007564652 @default.
- W4308308199 cites W2036492626 @default.
- W4308308199 cites W2038874766 @default.
- W4308308199 cites W2049395605 @default.
- W4308308199 cites W2057315521 @default.
- W4308308199 cites W2071243401 @default.
- W4308308199 cites W2080895359 @default.
- W4308308199 cites W2084623723 @default.
- W4308308199 cites W2086955153 @default.
- W4308308199 cites W2100601354 @default.
- W4308308199 cites W2107277218 @default.
- W4308308199 cites W2107979709 @default.
- W4308308199 cites W2108566316 @default.
- W4308308199 cites W2153947426 @default.
- W4308308199 cites W2310345822 @default.
- W4308308199 cites W2315697719 @default.
- W4308308199 cites W2325948500 @default.
- W4308308199 cites W2326061603 @default.
- W4308308199 cites W2335625435 @default.
- W4308308199 cites W2524655431 @default.
- W4308308199 cites W2600283512 @default.
- W4308308199 cites W2765487935 @default.
- W4308308199 cites W2792168869 @default.
- W4308308199 cites W2885660042 @default.
- W4308308199 cites W2901126365 @default.
- W4308308199 cites W2903197008 @default.
- W4308308199 cites W2905695683 @default.
- W4308308199 cites W2907693074 @default.
- W4308308199 cites W2911153487 @default.
- W4308308199 cites W2911871097 @default.
- W4308308199 cites W2912542956 @default.
- W4308308199 cites W2913594092 @default.
- W4308308199 cites W2913973433 @default.
- W4308308199 cites W2914317763 @default.
- W4308308199 cites W2916551902 @default.
- W4308308199 cites W2919616303 @default.
- W4308308199 cites W2944192337 @default.
- W4308308199 cites W2947039789 @default.
- W4308308199 cites W2952498883 @default.
- W4308308199 cites W2964402853 @default.
- W4308308199 cites W2969873639 @default.
- W4308308199 cites W2991152616 @default.
- W4308308199 cites W3021091076 @default.
- W4308308199 cites W3038140362 @default.
- W4308308199 doi "https://doi.org/10.1016/j.pestbp.2022.105284" @default.
- W4308308199 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36464384" @default.
- W4308308199 hasPublicationYear "2022" @default.
- W4308308199 type Work @default.
- W4308308199 citedByCount "1" @default.
- W4308308199 countsByYear W43083081992023 @default.
- W4308308199 crossrefType "journal-article" @default.
- W4308308199 hasAuthorship W4308308199A5003448004 @default.
- W4308308199 hasAuthorship W4308308199A5012278873 @default.
- W4308308199 hasAuthorship W4308308199A5023409516 @default.
- W4308308199 hasAuthorship W4308308199A5033172297 @default.
- W4308308199 hasAuthorship W4308308199A5040922074 @default.
- W4308308199 hasAuthorship W4308308199A5052342339 @default.
- W4308308199 hasAuthorship W4308308199A5062534699 @default.
- W4308308199 hasAuthorship W4308308199A5064072874 @default.
- W4308308199 hasAuthorship W4308308199A5070921750 @default.
- W4308308199 hasAuthorship W4308308199A5085822810 @default.
- W4308308199 hasAuthorship W4308308199A5089026355 @default.
- W4308308199 hasConcept C100701293 @default.
- W4308308199 hasConcept C104317684 @default.
- W4308308199 hasConcept C13002179 @default.
- W4308308199 hasConcept C142724271 @default.
- W4308308199 hasConcept C150149183 @default.
- W4308308199 hasConcept C173396325 @default.
- W4308308199 hasConcept C173758957 @default.
- W4308308199 hasConcept C204787440 @default.
- W4308308199 hasConcept C2776273252 @default.
- W4308308199 hasConcept C2776653637 @default.
- W4308308199 hasConcept C2780497538 @default.
- W4308308199 hasConcept C31241831 @default.
- W4308308199 hasConcept C32476901 @default.
- W4308308199 hasConcept C526171541 @default.
- W4308308199 hasConcept C55493867 @default.
- W4308308199 hasConcept C59822182 @default.
- W4308308199 hasConcept C62231903 @default.