Matches in SemOpenAlex for { <https://semopenalex.org/work/W4308333465> ?p ?o ?g. }
- W4308333465 endingPage "6532" @default.
- W4308333465 startingPage "6532" @default.
- W4308333465 abstract "Sticky platelet syndrome (SPS) is a thrombophilia caused by the increased aggregability of platelets in response to the addition of low concentrations of epinephrine (EPI) and/or adenosine diphosphate (ADP). Some of the single nucleotide polymorphisms (SNP), alleles and haplotypes of platelet glycoprotein receptors were proved to have a role in the etiology of thrombotic episodes When comparing SPS and the control group, in VEGFA rs3025039, the p value for both CC vs. TT and CT vs. TT analyses was <0.001. Interestingly, no minor TT genotype was present in the SPS group, suggesting the thrombotic pathogenesis of recurrent spontaneous abortions (RSA) in these patients. Moreover, we found a significant difference in the presence of AT containing a risky A allele and TT genotype of ALPP rs13026692 (p = 0.034) in SPS patients when compared with the controls. Additionally, we detected a decreased frequency of the GG (CC) genotype of FOXP3 rs3761548 in patients with SPS and RSA when compared with the control group (p value for the CC (GG) vs. AA (TT) 0.021). This might indicate an evolutionary protective mechanism of the A (T) allele in the SPS group against thrombotic complications in pregnancy. These results can be used for antithrombotic management in such pregnant patients." @default.
- W4308333465 created "2022-11-11" @default.
- W4308333465 creator A5000242519 @default.
- W4308333465 creator A5008216380 @default.
- W4308333465 creator A5022217670 @default.
- W4308333465 creator A5026785167 @default.
- W4308333465 creator A5027721504 @default.
- W4308333465 creator A5035575214 @default.
- W4308333465 creator A5037611327 @default.
- W4308333465 creator A5039196469 @default.
- W4308333465 creator A5039379906 @default.
- W4308333465 creator A5045661833 @default.
- W4308333465 creator A5046527235 @default.
- W4308333465 creator A5051622124 @default.
- W4308333465 creator A5057565684 @default.
- W4308333465 creator A5058319176 @default.
- W4308333465 creator A5067870093 @default.
- W4308333465 creator A5078846599 @default.
- W4308333465 creator A5082481355 @default.
- W4308333465 creator A5091536800 @default.
- W4308333465 date "2022-11-03" @default.
- W4308333465 modified "2023-10-18" @default.
- W4308333465 title "DNA Polymorphisms in Pregnant Women with Sticky Platelet Syndrome" @default.
- W4308333465 cites W1301197 @default.
- W4308333465 cites W1530836128 @default.
- W4308333465 cites W1549226126 @default.
- W4308333465 cites W1594087679 @default.
- W4308333465 cites W1840909092 @default.
- W4308333465 cites W1970313935 @default.
- W4308333465 cites W1973028577 @default.
- W4308333465 cites W1977440599 @default.
- W4308333465 cites W1987924345 @default.
- W4308333465 cites W1990655285 @default.
- W4308333465 cites W1994138782 @default.
- W4308333465 cites W2006531962 @default.
- W4308333465 cites W2060547922 @default.
- W4308333465 cites W2067161993 @default.
- W4308333465 cites W2069475666 @default.
- W4308333465 cites W2087032123 @default.
- W4308333465 cites W2096922932 @default.
- W4308333465 cites W2109150694 @default.
- W4308333465 cites W2117801166 @default.
- W4308333465 cites W2125117632 @default.
- W4308333465 cites W2156931207 @default.
- W4308333465 cites W2179427590 @default.
- W4308333465 cites W2324211603 @default.
- W4308333465 cites W2508884311 @default.
- W4308333465 cites W2526387176 @default.
- W4308333465 cites W2586078927 @default.
- W4308333465 cites W2614898738 @default.
- W4308333465 cites W2726190939 @default.
- W4308333465 cites W2797088672 @default.
- W4308333465 cites W2895710959 @default.
- W4308333465 cites W2909413122 @default.
- W4308333465 cites W2937697668 @default.
- W4308333465 cites W2941214467 @default.
- W4308333465 cites W2944089788 @default.
- W4308333465 cites W2954629625 @default.
- W4308333465 cites W2970736246 @default.
- W4308333465 cites W3000186786 @default.
- W4308333465 cites W3004123611 @default.
- W4308333465 cites W3014976545 @default.
- W4308333465 cites W3087040125 @default.
- W4308333465 cites W3153225875 @default.
- W4308333465 cites W3165112664 @default.
- W4308333465 cites W3194786999 @default.
- W4308333465 cites W4285150910 @default.
- W4308333465 doi "https://doi.org/10.3390/jcm11216532" @default.
- W4308333465 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36362759" @default.
- W4308333465 hasPublicationYear "2022" @default.
- W4308333465 type Work @default.
- W4308333465 citedByCount "0" @default.
- W4308333465 crossrefType "journal-article" @default.
- W4308333465 hasAuthorship W4308333465A5000242519 @default.
- W4308333465 hasAuthorship W4308333465A5008216380 @default.
- W4308333465 hasAuthorship W4308333465A5022217670 @default.
- W4308333465 hasAuthorship W4308333465A5026785167 @default.
- W4308333465 hasAuthorship W4308333465A5027721504 @default.
- W4308333465 hasAuthorship W4308333465A5035575214 @default.
- W4308333465 hasAuthorship W4308333465A5037611327 @default.
- W4308333465 hasAuthorship W4308333465A5039196469 @default.
- W4308333465 hasAuthorship W4308333465A5039379906 @default.
- W4308333465 hasAuthorship W4308333465A5045661833 @default.
- W4308333465 hasAuthorship W4308333465A5046527235 @default.
- W4308333465 hasAuthorship W4308333465A5051622124 @default.
- W4308333465 hasAuthorship W4308333465A5057565684 @default.
- W4308333465 hasAuthorship W4308333465A5058319176 @default.
- W4308333465 hasAuthorship W4308333465A5067870093 @default.
- W4308333465 hasAuthorship W4308333465A5078846599 @default.
- W4308333465 hasAuthorship W4308333465A5082481355 @default.
- W4308333465 hasAuthorship W4308333465A5091536800 @default.
- W4308333465 hasBestOaLocation W43083334651 @default.
- W4308333465 hasConcept C104317684 @default.
- W4308333465 hasConcept C126322002 @default.
- W4308333465 hasConcept C134018914 @default.
- W4308333465 hasConcept C135763542 @default.
- W4308333465 hasConcept C153209595 @default.
- W4308333465 hasConcept C180754005 @default.