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- W4308351787 endingPage "610" @default.
- W4308351787 startingPage "610" @default.
- W4308351787 abstract "Antimicrobial resistance and biofilm formation both present challenges to treatment of bacterial infections with conventional antibiotic therapy and serve as the impetus for development of improved therapeutic approaches. Mesenchymal stromal cell (MSC) therapy exerts an antimicrobial effect as demonstrated in multiple acute bacterial infection models. This effect can be enhanced by pre-conditioning the MSC with Toll or Nod-like receptor stimulation, termed activated cellular therapy (ACT). The purpose of this review is to summarize the current literature on mechanisms of antimicrobial activity of MSC with emphasis on enhanced effects through receptor agonism, and data supporting use of ACT in treatment of bacterial infections in veterinary species including dogs, cats, and horses with implications for further treatment applications. This review will advance the field’s understanding of the use of activated antimicrobial cellular therapy to treat infection, including mechanisms of action and potential therapeutic applications." @default.
- W4308351787 created "2022-11-11" @default.
- W4308351787 creator A5048819993 @default.
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- W4308351787 creator A5053589592 @default.
- W4308351787 creator A5063835756 @default.
- W4308351787 creator A5083005720 @default.
- W4308351787 date "2022-11-04" @default.
- W4308351787 modified "2023-10-01" @default.
- W4308351787 title "Immune Activated Cellular Therapy for Drug Resistant Infections: Rationale, Mechanisms, and Implications for Veterinary Medicine" @default.
- W4308351787 cites W1141274631 @default.
- W4308351787 cites W1543002776 @default.
- W4308351787 cites W1755096708 @default.
- W4308351787 cites W1984244519 @default.
- W4308351787 cites W2002661570 @default.
- W4308351787 cites W2005349078 @default.
- W4308351787 cites W2009626854 @default.
- W4308351787 cites W2024376207 @default.
- W4308351787 cites W2037378549 @default.
- W4308351787 cites W2041111932 @default.
- W4308351787 cites W2046556649 @default.
- W4308351787 cites W2053455572 @default.
- W4308351787 cites W2057013721 @default.
- W4308351787 cites W2057580939 @default.
- W4308351787 cites W2064647582 @default.
- W4308351787 cites W2073024911 @default.
- W4308351787 cites W2076853786 @default.
- W4308351787 cites W2079678573 @default.
- W4308351787 cites W2082728447 @default.
- W4308351787 cites W2084978938 @default.
- W4308351787 cites W2088964957 @default.
- W4308351787 cites W2092095100 @default.
- W4308351787 cites W2092139454 @default.
- W4308351787 cites W2094024512 @default.
- W4308351787 cites W2117220410 @default.
- W4308351787 cites W2119256996 @default.
- W4308351787 cites W2136408492 @default.
- W4308351787 cites W2142181216 @default.
- W4308351787 cites W2144337206 @default.
- W4308351787 cites W2145650199 @default.
- W4308351787 cites W2159400425 @default.
- W4308351787 cites W2170420681 @default.
- W4308351787 cites W2189116376 @default.
- W4308351787 cites W2292313894 @default.
- W4308351787 cites W2334089497 @default.
- W4308351787 cites W2429852311 @default.
- W4308351787 cites W2472417552 @default.
- W4308351787 cites W2481614760 @default.
- W4308351787 cites W2522780273 @default.
- W4308351787 cites W2526446404 @default.
- W4308351787 cites W2563512435 @default.
- W4308351787 cites W2564922232 @default.
- W4308351787 cites W2565686633 @default.
- W4308351787 cites W2580543265 @default.
- W4308351787 cites W2581990958 @default.
- W4308351787 cites W2603921207 @default.
- W4308351787 cites W2731981206 @default.
- W4308351787 cites W2732839963 @default.
- W4308351787 cites W2738261657 @default.
- W4308351787 cites W2744021789 @default.
- W4308351787 cites W2747982145 @default.
- W4308351787 cites W2767055058 @default.
- W4308351787 cites W2783676704 @default.
- W4308351787 cites W2789450435 @default.
- W4308351787 cites W2789592679 @default.
- W4308351787 cites W2789704095 @default.
- W4308351787 cites W2793921974 @default.
- W4308351787 cites W2804436828 @default.
- W4308351787 cites W2805661897 @default.
- W4308351787 cites W2865529063 @default.
- W4308351787 cites W2884407806 @default.
- W4308351787 cites W2886664573 @default.
- W4308351787 cites W2890333745 @default.
- W4308351787 cites W2895841717 @default.
- W4308351787 cites W2897109701 @default.
- W4308351787 cites W2898050977 @default.
- W4308351787 cites W2913962492 @default.
- W4308351787 cites W2921238631 @default.
- W4308351787 cites W2982871573 @default.
- W4308351787 cites W2985019389 @default.
- W4308351787 cites W3011328286 @default.
- W4308351787 cites W3013540420 @default.
- W4308351787 cites W3088431078 @default.
- W4308351787 cites W3088933438 @default.
- W4308351787 cites W3107603562 @default.
- W4308351787 cites W3115130414 @default.
- W4308351787 cites W3126543303 @default.
- W4308351787 cites W3129135229 @default.
- W4308351787 cites W3139828926 @default.
- W4308351787 cites W3157748677 @default.
- W4308351787 cites W3185624974 @default.
- W4308351787 cites W3201601156 @default.
- W4308351787 cites W341074669 @default.
- W4308351787 cites W4200276048 @default.
- W4308351787 cites W4206304887 @default.
- W4308351787 cites W4207076283 @default.
- W4308351787 cites W4214861479 @default.
- W4308351787 cites W4220711864 @default.