Matches in SemOpenAlex for { <https://semopenalex.org/work/W4308365532> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W4308365532 abstract "Genome-wide maps of epigenetic modifications are powerful resources for non-coding genome annotation. Maps of multiple epigenetics marks have been integrated into cell or tissue type-specific chromatin state annotations for many cell or tissue types. With the increasing availability of multiple chromatin state maps for biologically similar samples, there is a need for methods that can effectively summarize the information about chromatin state annotations within groups of samples and identify differences across groups of samples at a high resolution.We developed CSREP, which takes as input chromatin state annotations for a group of samples. CSREP then probabilistically estimates the state at each genomic position and derives a representative chromatin state map for the group. CSREP uses an ensemble of multi-class logistic regression classifiers that predict the chromatin state assignment of each sample given the state maps from all other samples. The difference in CSREP's probability assignments for the two groups can be used to identify genomic locations with differential chromatin state assignments. Using groups of chromatin state maps of a diverse set of cell and tissue types, we demonstrate the advantages of using CSREP to summarize chromatin state maps and identify biologically relevant differences between groups at a high resolution.The CSREP source code and generated data are available at http://github.com/ernstlab/csrep.Supplementary data are available at Bioinformatics online." @default.
- W4308365532 created "2022-11-11" @default.
- W4308365532 creator A5009275502 @default.
- W4308365532 creator A5076507980 @default.
- W4308365532 creator A5085146816 @default.
- W4308365532 creator A5088682596 @default.
- W4308365532 date "2022-11-07" @default.
- W4308365532 modified "2023-10-17" @default.
- W4308365532 title "A framework for group-wise summarization and comparison of chromatin state annotations" @default.
- W4308365532 cites W1161512630 @default.
- W4308365532 cites W1981030303 @default.
- W4308365532 cites W2002793113 @default.
- W4308365532 cites W2015416439 @default.
- W4308365532 cites W2018363492 @default.
- W4308365532 cites W2023825334 @default.
- W4308365532 cites W2044826047 @default.
- W4308365532 cites W2050794883 @default.
- W4308365532 cites W2076154138 @default.
- W4308365532 cites W2082662254 @default.
- W4308365532 cites W2102619694 @default.
- W4308365532 cites W2110417468 @default.
- W4308365532 cites W2117792884 @default.
- W4308365532 cites W2132241624 @default.
- W4308365532 cites W2157232603 @default.
- W4308365532 cites W2157750191 @default.
- W4308365532 cites W2161435642 @default.
- W4308365532 cites W2259938310 @default.
- W4308365532 cites W2624164746 @default.
- W4308365532 cites W2787894218 @default.
- W4308365532 cites W2789853766 @default.
- W4308365532 cites W2951217386 @default.
- W4308365532 cites W3110183739 @default.
- W4308365532 cites W3122109253 @default.
- W4308365532 cites W3127556601 @default.
- W4308365532 cites W3133859624 @default.
- W4308365532 cites W3207124649 @default.
- W4308365532 cites W4226239358 @default.
- W4308365532 cites W4230875896 @default.
- W4308365532 doi "https://doi.org/10.1093/bioinformatics/btac722" @default.
- W4308365532 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36342196" @default.
- W4308365532 hasPublicationYear "2022" @default.
- W4308365532 type Work @default.
- W4308365532 citedByCount "2" @default.
- W4308365532 countsByYear W43083655322023 @default.
- W4308365532 crossrefType "journal-article" @default.
- W4308365532 hasAuthorship W4308365532A5009275502 @default.
- W4308365532 hasAuthorship W4308365532A5076507980 @default.
- W4308365532 hasAuthorship W4308365532A5085146816 @default.
- W4308365532 hasAuthorship W4308365532A5088682596 @default.
- W4308365532 hasBestOaLocation W43083655321 @default.
- W4308365532 hasConcept C104317684 @default.
- W4308365532 hasConcept C137338518 @default.
- W4308365532 hasConcept C141231307 @default.
- W4308365532 hasConcept C154945302 @default.
- W4308365532 hasConcept C167227067 @default.
- W4308365532 hasConcept C170858558 @default.
- W4308365532 hasConcept C2776321320 @default.
- W4308365532 hasConcept C41008148 @default.
- W4308365532 hasConcept C41091548 @default.
- W4308365532 hasConcept C54355233 @default.
- W4308365532 hasConcept C70721500 @default.
- W4308365532 hasConcept C83640560 @default.
- W4308365532 hasConcept C86803240 @default.
- W4308365532 hasConceptScore W4308365532C104317684 @default.
- W4308365532 hasConceptScore W4308365532C137338518 @default.
- W4308365532 hasConceptScore W4308365532C141231307 @default.
- W4308365532 hasConceptScore W4308365532C154945302 @default.
- W4308365532 hasConceptScore W4308365532C167227067 @default.
- W4308365532 hasConceptScore W4308365532C170858558 @default.
- W4308365532 hasConceptScore W4308365532C2776321320 @default.
- W4308365532 hasConceptScore W4308365532C41008148 @default.
- W4308365532 hasConceptScore W4308365532C41091548 @default.
- W4308365532 hasConceptScore W4308365532C54355233 @default.
- W4308365532 hasConceptScore W4308365532C70721500 @default.
- W4308365532 hasConceptScore W4308365532C83640560 @default.
- W4308365532 hasConceptScore W4308365532C86803240 @default.
- W4308365532 hasFunder F4320306076 @default.
- W4308365532 hasFunder F4320332161 @default.
- W4308365532 hasIssue "1" @default.
- W4308365532 hasLocation W43083655321 @default.
- W4308365532 hasLocation W43083655322 @default.
- W4308365532 hasLocation W43083655323 @default.
- W4308365532 hasOpenAccess W4308365532 @default.
- W4308365532 hasPrimaryLocation W43083655321 @default.
- W4308365532 hasRelatedWork W1998365877 @default.
- W4308365532 hasRelatedWork W2135993011 @default.
- W4308365532 hasRelatedWork W2172833929 @default.
- W4308365532 hasRelatedWork W2558699479 @default.
- W4308365532 hasRelatedWork W2884361791 @default.
- W4308365532 hasRelatedWork W2887293316 @default.
- W4308365532 hasRelatedWork W3032827958 @default.
- W4308365532 hasRelatedWork W3133068219 @default.
- W4308365532 hasRelatedWork W3162580226 @default.
- W4308365532 hasRelatedWork W4315786991 @default.
- W4308365532 hasVolume "39" @default.
- W4308365532 isParatext "false" @default.
- W4308365532 isRetracted "false" @default.
- W4308365532 workType "article" @default.