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- W4308367632 abstract "Objectives To examine the association between physical activity, sedentary time, and physical fitness with the shapes of subcortical brain structures in children with overweight/obesity. Further, we analyzed whether differences in the shapes of subcortical brain structures were related to intelligence. We hypothesized that those children with higher physical activity levels, lower sedentary time, and better fitness, would show greater expansion of the brain regions analyzed, and these expansions would be associated with higher intelligence. Study Design 100 children (10.0 ± 1.1 years, 40 girls) were included in the analyses. Physical activity and sedentary time were measured by accelerometry, and physical fitness was evaluated by a fitness battery. Shapes of subcortical brain structures were assessed by magnetic resonance imaging. Intelligence was measured by the Kaufmann Brief Intelligence test. Results Physical activity was related to expansion of the right/left pallidum, right/left putamen, and right thalamus ( p < 0.05). Higher sedentary time was related to contraction of the left thalamus and right nucleus accumbens ( p < 0.05). Higher levels of cardiorespiratory fitness were associated with expansion of the right amygdala ( p = 0.022). Greater strength in the upper‐limb was related to expansion of the right/left pallidum and the left nucleus accumbens ( p < 0.038), and contraction of the left amygdala ( p = 0.030). Better speed‐agility was associated with expansion of the left nucleus accumbens ( p = 0.036). Physical activity‐ and fitness‐related expansion of the right pallidum was associated with higher intelligence (all p < 0.05). Conclusion Physical activity, sedentary time, and physical fitness were significantly related to the shapes of subcortical brain structures, which in turn were related to intelligence in children with overweight/obesity." @default.
- W4308367632 created "2022-11-11" @default.
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- W4308367632 date "2022-11-22" @default.
- W4308367632 modified "2023-10-18" @default.
- W4308367632 title "Physical activity, sedentary time, and fitness in relation to brain shapes in children with overweight/obesity: Links to intelligence" @default.
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- W4308367632 doi "https://doi.org/10.1111/sms.14263" @default.
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