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- W4308368001 abstract "Abstract Iron deficiency is the most common nutrient deficiency in the world, affecting over 20% of premenopausal women worldwide. Oral iron supplementation is often the first‐line treatment for the acute and chronic management of iron deficiency due to its ease and accessibility. However, there is no consensus on the optimal formulation or dosing strategy, or which patients should be preferentially treated with intravenous iron. Management of iron deficiency is complicated by the hepcidin‐ferroportin iron regulatory pathway, which has evolved to prevent iron overload and thereby creates an inherent limit on gastrointestinal iron uptake and efficacy of oral iron. Unabsorbed iron propagates many of the side effects that complicate oral iron use including dyspepsia and constipation, all of which can thus be exacerbated by excessive oral iron doses. Daily low dose and every other day dosing protocols have attempted to bypass this physiologic bottleneck to allow for effective absorption and limit side effects; however, this approach has still resulted in low fractional iron absorption. In the following manuscript, we review the pathophysiology of iron absorption and current evidence for various preparations of oral iron. Lastly, we highlight opportunities for further study to advance the care of individuals affected by iron deficiency." @default.
- W4308368001 created "2022-11-11" @default.
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- W4308368001 date "2022-11-20" @default.
- W4308368001 modified "2023-09-26" @default.
- W4308368001 title "The role of oral iron in the treatment of adults with iron deficiency" @default.
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- W4308368001 cites W1863616792 @default.
- W4308368001 cites W1892003742 @default.
- W4308368001 cites W1913390793 @default.
- W4308368001 cites W1982682980 @default.
- W4308368001 cites W2010047985 @default.
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- W4308368001 cites W2022735993 @default.
- W4308368001 cites W2028244138 @default.
- W4308368001 cites W2049123117 @default.
- W4308368001 cites W2066006975 @default.
- W4308368001 cites W2073782883 @default.
- W4308368001 cites W2102170108 @default.
- W4308368001 cites W2104624275 @default.
- W4308368001 cites W2106489922 @default.
- W4308368001 cites W2106642565 @default.
- W4308368001 cites W2110302416 @default.
- W4308368001 cites W2114456183 @default.
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- W4308368001 doi "https://doi.org/10.1111/ejh.13892" @default.
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