FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4308371146> ?p ?o ?g. }

• W4308371146 endingPage "1621" @default.
• W4308371146 startingPage "1612" @default.
• W4308371146 abstract "Noninvasive Prenatal Diagnosis has recently been introduced for a limited number of monogenetic disorders. However, the majority of DNA diagnostics still require fetal material obtained using an invasive test. Recently, a novel technique, TRIC (Trophoblast Retrieval and Isolation from the Cervix), has been described, which collects fetal trophoblast cells by endocervical sampling. Since this technique has not been successfully replicated by other groups, we aimed to achieve this in the current study.Pregnant women referred for transvaginal chorionic villous sampling (CVS) were asked for an endocervical sample prior to CVS. The TRIC samples were processed to isolate trophoblast DNA. TRIC DNA was used in ForenSeq to determine the amount of maternal DNA contamination, and for Sanger sequencing in case of a monogenic disorder.23%-44% of samples had a sufficiently high fetal DNA fraction to allow genetic testing, as calculated by Sanger sequencing and ForenSeq, respectively.We have been able to successfully replicate the TRIC protocol, although with a much lower success rate as described by the original study performing TRIC. As we obtained the samples in the actual clinical setting envisioned, the method in its current setup is not advisable for use in prenatal diagnostics." @default.
• W4308371146 created "2022-11-11" @default.
• W4308371146 creator A5005873671 @default.
• W4308371146 creator A5006722581 @default.
• W4308371146 creator A5028395715 @default.
• W4308371146 creator A5032251149 @default.
• W4308371146 creator A5061588461 @default.
• W4308371146 creator A5066077395 @default.
• W4308371146 creator A5078464806 @default.
• W4308371146 creator A5089627054 @default.
• W4308371146 creator A5090827008 @default.
• W4308371146 date "2022-11-12" @default.
• W4308371146 modified "2023-10-16" @default.
• W4308371146 title "Tricky TRIC: A replication study using trophoblast retrieval and isolation from the cervix to study genetic birth defects" @default.
• W4308371146 cites W1576120545 @default.
• W4308371146 cites W1857975231 @default.
• W4308371146 cites W2025346732 @default.
• W4308371146 cites W2068894833 @default.
• W4308371146 cites W2088141357 @default.
• W4308371146 cites W2120898211 @default.
• W4308371146 cites W2132362775 @default.
• W4308371146 cites W2132640413 @default.
• W4308371146 cites W2258532034 @default.
• W4308371146 cites W2546698177 @default.
• W4308371146 cites W2945069441 @default.
• W4308371146 cites W3006663758 @default.
• W4308371146 cites W3024783467 @default.
• W4308371146 cites W3048238015 @default.
• W4308371146 cites W4205588900 @default.
• W4308371146 cites W4246806847 @default.
• W4308371146 cites W4280508723 @default.
• W4308371146 cites W4308371146 @default.
• W4308371146 doi "https://doi.org/10.1002/pd.6260" @default.
• W4308371146 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36336875" @default.
• W4308371146 hasPublicationYear "2022" @default.
• W4308371146 type Work @default.
• W4308371146 citedByCount "2" @default.
• W4308371146 countsByYear W43083711462022 @default.
• W4308371146 countsByYear W43083711462023 @default.
• W4308371146 crossrefType "journal-article" @default.
• W4308371146 hasAuthorship W4308371146A5005873671 @default.
• W4308371146 hasAuthorship W4308371146A5006722581 @default.
• W4308371146 hasAuthorship W4308371146A5028395715 @default.
• W4308371146 hasAuthorship W4308371146A5032251149 @default.
• W4308371146 hasAuthorship W4308371146A5061588461 @default.
• W4308371146 hasAuthorship W4308371146A5066077395 @default.
• W4308371146 hasAuthorship W4308371146A5078464806 @default.
• W4308371146 hasAuthorship W4308371146A5089627054 @default.
• W4308371146 hasAuthorship W4308371146A5090827008 @default.
• W4308371146 hasBestOaLocation W43083711461 @default.
• W4308371146 hasConcept C106131492 @default.
• W4308371146 hasConcept C121608353 @default.
• W4308371146 hasConcept C131872663 @default.
• W4308371146 hasConcept C140779682 @default.
• W4308371146 hasConcept C172680121 @default.
• W4308371146 hasConcept C2776555163 @default.
• W4308371146 hasConcept C2776953305 @default.
• W4308371146 hasConcept C2777495146 @default.
• W4308371146 hasConcept C2777740455 @default.
• W4308371146 hasConcept C2778258057 @default.
• W4308371146 hasConcept C2779234561 @default.
• W4308371146 hasConcept C31972630 @default.
• W4308371146 hasConcept C41008148 @default.
• W4308371146 hasConcept C51679486 @default.
• W4308371146 hasConcept C54355233 @default.
• W4308371146 hasConcept C552990157 @default.
• W4308371146 hasConcept C71924100 @default.
• W4308371146 hasConcept C76818968 @default.
• W4308371146 hasConcept C86803240 @default.
• W4308371146 hasConceptScore W4308371146C106131492 @default.
• W4308371146 hasConceptScore W4308371146C121608353 @default.
• W4308371146 hasConceptScore W4308371146C131872663 @default.
• W4308371146 hasConceptScore W4308371146C140779682 @default.
• W4308371146 hasConceptScore W4308371146C172680121 @default.
• W4308371146 hasConceptScore W4308371146C2776555163 @default.
• W4308371146 hasConceptScore W4308371146C2776953305 @default.
• W4308371146 hasConceptScore W4308371146C2777495146 @default.
• W4308371146 hasConceptScore W4308371146C2777740455 @default.
• W4308371146 hasConceptScore W4308371146C2778258057 @default.
• W4308371146 hasConceptScore W4308371146C2779234561 @default.
• W4308371146 hasConceptScore W4308371146C31972630 @default.
• W4308371146 hasConceptScore W4308371146C41008148 @default.
• W4308371146 hasConceptScore W4308371146C51679486 @default.
• W4308371146 hasConceptScore W4308371146C54355233 @default.
• W4308371146 hasConceptScore W4308371146C552990157 @default.
• W4308371146 hasConceptScore W4308371146C71924100 @default.
• W4308371146 hasConceptScore W4308371146C76818968 @default.
• W4308371146 hasConceptScore W4308371146C86803240 @default.
• W4308371146 hasIssue "13" @default.
• W4308371146 hasLocation W43083711461 @default.
• W4308371146 hasLocation W43083711462 @default.
• W4308371146 hasLocation W43083711463 @default.
• W4308371146 hasOpenAccess W4308371146 @default.
• W4308371146 hasPrimaryLocation W43083711461 @default.
• W4308371146 hasRelatedWork W1969022859 @default.
• W4308371146 hasRelatedWork W1973226671 @default.
• W4308371146 hasRelatedWork W2002579676 @default.
• W4308371146 hasRelatedWork W2041651589 @default.

• next