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- W4308373606 abstract "Intravesical immunotherapy with bacillus Calmette-Guerin (BCG) is considered as the standard treatment for non-muscle invasive bladder cancer with high risk of recurrence and progression.To report a case of granulomatous cystitis in a patient receiving BCG intravesical therapy for urothelial carcinoma.A 63-year-old man underwent BCG treatment for a bladder tumor with pathological diagnosis of T1G3 urothelial carcinoma. Five months later, trans urethral resection (TUR) of bladder was performed for an erythematous lesion, with results of post-BCG cystitis. Two years later, the patient presented with hematuria and with suspicious findings in the cystoscopy (extensive fibrin-covered and calcified lesions in the bladder) and a bladder TUR was done.The histopathological study showed granulomatous cystitis with necrosis and the presence of BAAR compatible with post-BCG origin. In the mycobacterial culture, M. bovis grew, and treatment was initiated. A cystography was performed on suspicion of a microbladder on CT with secondary vesicoureteral reflux, confirmed in this test. It was decided to perform a radical cystectomy. Histopathology reported post-BCG granulomatous cystitis and prostatitis.After BCG treatment, if symptoms or images are suggestive of granulomatous cystitis, a study of mycobacterial infection should be started to avoid the development of complications, such as the microbladder as in the case we present." @default.
- W4308373606 created "2022-11-11" @default.
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- W4308373606 date "2022-01-01" @default.
- W4308373606 modified "2023-09-27" @default.
- W4308373606 title "Microbladder due to Granulomatous Cystitis Secondary to BCG Treatment" @default.
- W4308373606 doi "https://doi.org/10.56434/j.arch.esp.urol.20227508.105" @default.
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