FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4308396101> ?p ?o ?g. }

• W4308396101 abstract "<h3>Background</h3> Background: Despite regulatory approval and advancements of immune-based interventions over the last decade, significant obstacles remain to be overcome before the full potential of immunotherapy can be realized to improve outcomes for cancer patients [1,3]. The NCI Cancer Moonshot Immuno-Oncology Translational Network (IOTN) was established in 2018 with the overarching goal of improving the efficacy, durability, and safety of immunotherapy across the spectrum of human cancers, as well as developing immunoprevention approaches that will prevent cancers before they occur.^1,2 <h3>Methods</h3> The IOTN consortium, consisting of 29 research project awards spanning 33 institutions, conducts translational research focused on four thematic areas: Immunotherapy, Immuno-Engineering to improve immuno-therapy (i3), Mitigating immune related adverse events (irAE) and Immuno-Prevention.^{2, 3} At each stage of the IOTN9s translational studies, the Data Management Resource Sharing Center (DMRC) serves as an administrative and analytic hub, focusing on lowering barriers for access to analytic expertise, improving network productivity, maintaining a high standard for data collection and management, and fostering a collaborative and supportive research community. <h3>Results</h3> The DMRC has developed centralized infrastructures to enhance the IOTN’s research output, including a collection of publicly accessible and scalable resource sharing catalogs for Data, Model, Software and Clinical Trials.⁴ In addition to supporting intra-network collaboration, the DMRC engaged cross-moonshot communication by hosting and coordinating a number of meetings and workshops, including the inaugural Cancer Moonshot Collaborative Meeting and monthly NCI Cancer Moonshot Seminar Series.^{5, 6} The DMRC in collaboration with SITC has organized the highly popular SITC-NCI webinar series on “Computational Science in Immuno-Oncology”, fostering collaboration, communication and outreach to the broader communities.⁷ <h3>Conclusions</h3> The IOTN9s consortium structure, strengthened by the DMRC9s centralized management, analytical, and data integration supports, has facilitated effective intra- and inter-moonshot communication and enabled collaborative translational studies. <h3>Acknowledgements</h3> This work was supported by IOTN Moonshot grant U24CA232979-01 <h3>References</h3> Jacks T, Jaffee E and Singer D. Blue Ribbon Panel Co-Chairs (2016) Cancer Moonshot Blue Ribbon Panel Report. <i>National Cancer Institute</i>, Bethesda, MD. Adult Immunotherapy Network Fact Sheet [https://www.cancer.gov/research/key-initiatives/moonshot-cancer-initiative/implementation/adult-immunotherapy-network/fact-sheet.pdf] Annapragada A, Sikora A, Bollard C, <i>et al</i>. Cancer Moonshot Immuno-Oncology Translational Network (IOTN): accelerating the clinical translation of basic discoveries for improving immunotherapy and immunoprevention of cancer. <i>J Immunother Cancer</i> 2020;<b>8</b>:e00079. Immuno-Oncology Translational Network. IOTN Resource Sharing Catalogs. 2022. Available from: https://www.iotnmoonshot.org/en/resources/all-resources/. National Cancer Institute. Cancer Moonshot Workshop Highlights Advances – National Cancer Institute 2020. Available from: https://www.cancer.gov/news-events/cancer-currents-blog/2020/cancer-moonshot-nci-workshop-advances-collaboration. National Cancer Institute. Cancer Moonshot^SM Seminar Series [online workshop series], September 24, 2020-May 26, 2022: National Cancer Institute; 2021. Available from: https://www.cancer.gov/research/key-initiatives/moonshot-cancer-initiative/seminar-series. 18. Society for Immunotherapy of Cancer. SITC-NCI Computational Immuno-oncology Webinar Series [online workshop series], May 11, 2021-December 17, 2022: Society for Immunotherapy of Cancer (SITC) in partnership with the National Cancer Institute (NCI); 2021 Available from: https://www.sitcancer.org/education/computational." @default.
• W4308396101 created "2022-11-11" @default.
• W4308396101 creator A5009400324 @default.
• W4308396101 creator A5014295844 @default.
• W4308396101 creator A5069146590 @default.
• W4308396101 creator A5078547538 @default.
• W4308396101 creator A5090396131 @default.
• W4308396101 date "2022-11-01" @default.
• W4308396101 modified "2023-09-25" @default.
• W4308396101 title "929 The data management and resource sharing center for the cancer moonshot immuno-oncology translational network" @default.
• W4308396101 doi "https://doi.org/10.1136/jitc-2022-sitc2022.0929" @default.
• W4308396101 hasPublicationYear "2022" @default.
• W4308396101 type Work @default.
• W4308396101 citedByCount "0" @default.
• W4308396101 crossrefType "proceedings-article" @default.
• W4308396101 hasAuthorship W4308396101A5009400324 @default.
• W4308396101 hasAuthorship W4308396101A5014295844 @default.
• W4308396101 hasAuthorship W4308396101A5069146590 @default.
• W4308396101 hasAuthorship W4308396101A5078547538 @default.
• W4308396101 hasAuthorship W4308396101A5090396131 @default.
• W4308396101 hasBestOaLocation W43083961011 @default.
• W4308396101 hasConcept C121608353 @default.
• W4308396101 hasConcept C126322002 @default.
• W4308396101 hasConcept C128544194 @default.
• W4308396101 hasConcept C142724271 @default.
• W4308396101 hasConcept C144133560 @default.
• W4308396101 hasConcept C159110408 @default.
• W4308396101 hasConcept C204787440 @default.
• W4308396101 hasConcept C206345919 @default.
• W4308396101 hasConcept C27415008 @default.
• W4308396101 hasConcept C2777701055 @default.
• W4308396101 hasConcept C2779965156 @default.
• W4308396101 hasConcept C31258907 @default.
• W4308396101 hasConcept C41008148 @default.
• W4308396101 hasConcept C56739046 @default.
• W4308396101 hasConcept C71924100 @default.
• W4308396101 hasConceptScore W4308396101C121608353 @default.
• W4308396101 hasConceptScore W4308396101C126322002 @default.
• W4308396101 hasConceptScore W4308396101C128544194 @default.
• W4308396101 hasConceptScore W4308396101C142724271 @default.
• W4308396101 hasConceptScore W4308396101C144133560 @default.
• W4308396101 hasConceptScore W4308396101C159110408 @default.
• W4308396101 hasConceptScore W4308396101C204787440 @default.
• W4308396101 hasConceptScore W4308396101C206345919 @default.
• W4308396101 hasConceptScore W4308396101C27415008 @default.
• W4308396101 hasConceptScore W4308396101C2777701055 @default.
• W4308396101 hasConceptScore W4308396101C2779965156 @default.
• W4308396101 hasConceptScore W4308396101C31258907 @default.
• W4308396101 hasConceptScore W4308396101C41008148 @default.
• W4308396101 hasConceptScore W4308396101C56739046 @default.
• W4308396101 hasConceptScore W4308396101C71924100 @default.
• W4308396101 hasLocation W43083961011 @default.
• W4308396101 hasOpenAccess W4308396101 @default.
• W4308396101 hasPrimaryLocation W43083961011 @default.
• W4308396101 hasRelatedWork W2030612376 @default.
• W4308396101 hasRelatedWork W2055898001 @default.
• W4308396101 hasRelatedWork W2365364931 @default.
• W4308396101 hasRelatedWork W2418638721 @default.
• W4308396101 hasRelatedWork W2617307344 @default.
• W4308396101 hasRelatedWork W2748952813 @default.
• W4308396101 hasRelatedWork W2899084033 @default.
• W4308396101 hasRelatedWork W4290614473 @default.
• W4308396101 hasRelatedWork W4296137504 @default.
• W4308396101 hasRelatedWork W4309844170 @default.
• W4308396101 isParatext "false" @default.
• W4308396101 isRetracted "false" @default.
• W4308396101 workType "article" @default.