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- W4308437659 abstract "As various nanoparticles (NPs) are increasingly being used in nanomedicine products for more effective and less toxic therapy and diagnosis of diseases, there is a growing need to understand their biological fate in different sexes. Herein, we report a proof-of-concept result of sex-specific protein corona compositions on the surface of silica NPs as a function of their size and porosity upon incubation with plasma proteins of female and male BALB/c mice. Our results demonstrate substantial differences between male and female protein corona profiles on the surface of silica nanoparticles. By comparing protein abundances between male and female protein coronas of mesoporous silica nanoparticles and Stöber silica nanoparticles of ∼100, 50, and 100 nm in diameter, respectively, we detected 17, 4, and 4 distinct proteins, respectively, that were found at significantly different concentrations for these constructs. These initial findings demonstrate that animal sex can influence protein corona formation on silica NPs as a function of the physicochemical properties. A more thorough consideration of the role of plasma sex would enable nanomedicine community to design and develop safer and more efficient diagnostic and therapeutic nanomedicine products for both sexes." @default.
- W4308437659 created "2022-11-11" @default.
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- W4308437659 date "2022-11-07" @default.
- W4308437659 modified "2023-10-10" @default.
- W4308437659 title "Sex-Specific Silica Nanoparticle Protein Corona Compositions Exposed to Male and Female BALB/c Mice Plasmas" @default.
- W4308437659 cites W1667348892 @default.
- W4308437659 cites W1944309693 @default.
- W4308437659 cites W1961515348 @default.
- W4308437659 cites W1973831032 @default.
- W4308437659 cites W1976350040 @default.
- W4308437659 cites W1984382389 @default.
- W4308437659 cites W1988331953 @default.
- W4308437659 cites W1995704440 @default.
- W4308437659 cites W2000576209 @default.
- W4308437659 cites W2011088255 @default.
- W4308437659 cites W2019135221 @default.
- W4308437659 cites W2023202045 @default.
- W4308437659 cites W2037021965 @default.
- W4308437659 cites W2038246612 @default.
- W4308437659 cites W2054981131 @default.
- W4308437659 cites W2063819412 @default.
- W4308437659 cites W2077982494 @default.
- W4308437659 cites W2079181134 @default.
- W4308437659 cites W2102618395 @default.
- W4308437659 cites W2110634891 @default.
- W4308437659 cites W2113023473 @default.
- W4308437659 cites W2119876907 @default.
- W4308437659 cites W2125660301 @default.
- W4308437659 cites W2134414477 @default.
- W4308437659 cites W2145732128 @default.
- W4308437659 cites W2157016784 @default.
- W4308437659 cites W2160771041 @default.
- W4308437659 cites W2161946327 @default.
- W4308437659 cites W2164872331 @default.
- W4308437659 cites W2165823785 @default.
- W4308437659 cites W2231472752 @default.
- W4308437659 cites W2344644350 @default.
- W4308437659 cites W2404192110 @default.
- W4308437659 cites W2551032364 @default.
- W4308437659 cites W2570618306 @default.
- W4308437659 cites W2591992124 @default.
- W4308437659 cites W2598924229 @default.
- W4308437659 cites W2736736229 @default.
- W4308437659 cites W2736913410 @default.
- W4308437659 cites W2753485205 @default.
- W4308437659 cites W2759363431 @default.
- W4308437659 cites W2765915913 @default.
- W4308437659 cites W2770722600 @default.
- W4308437659 cites W2772995273 @default.
- W4308437659 cites W2780719111 @default.
- W4308437659 cites W2782084553 @default.
- W4308437659 cites W2789322787 @default.
- W4308437659 cites W2792416781 @default.
- W4308437659 cites W2793512502 @default.
- W4308437659 cites W2893128788 @default.
- W4308437659 cites W2893919806 @default.
- W4308437659 cites W2900125153 @default.
- W4308437659 cites W2900612430 @default.
- W4308437659 cites W2943717490 @default.
- W4308437659 cites W2943764712 @default.
- W4308437659 cites W2949075248 @default.
- W4308437659 cites W2949257671 @default.
- W4308437659 cites W2950967976 @default.
- W4308437659 cites W2951277997 @default.
- W4308437659 cites W2960078955 @default.
- W4308437659 cites W2972142417 @default.
- W4308437659 cites W2982170158 @default.
- W4308437659 cites W2998781929 @default.
- W4308437659 cites W3000887270 @default.
- W4308437659 cites W3027701553 @default.
- W4308437659 cites W3040299981 @default.
- W4308437659 cites W3043870236 @default.
- W4308437659 cites W3092427457 @default.
- W4308437659 cites W3103608461 @default.
- W4308437659 cites W3106143834 @default.
- W4308437659 cites W3123389906 @default.
- W4308437659 cites W3128098186 @default.
- W4308437659 cites W3161277716 @default.
- W4308437659 cites W3161392453 @default.
- W4308437659 cites W3196316669 @default.
- W4308437659 cites W3197838814 @default.
- W4308437659 cites W3203776961 @default.
- W4308437659 cites W4206592323 @default.
- W4308437659 cites W4210461181 @default.
- W4308437659 cites W4220873042 @default.
- W4308437659 cites W4251095359 @default.
- W4308437659 cites W4307437392 @default.
- W4308437659 doi "https://doi.org/10.1021/acsbiomedchemau.2c00040" @default.
- W4308437659 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36820312" @default.
- W4308437659 hasPublicationYear "2022" @default.