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- W4308443752 abstract "The complex interaction between the intestinal mucosa, the gut microbiota, and the diet balances the host physiological homeostasis and is fundamental for the maximal genetic potential of production animals. However, factors such as chemical and physical characteristics of the diet and/or environmental stressors can continuously affect this balance, potentially inducing a state of chronic low-grade inflammation in the gut, where inflammatory parameters are present and demanding energy, but not in enough intensity to provoke clinical manifestations. It’s vital to expand the understanding of inflammation dynamics and of how they compromise the function activity and microscopic morphology of the intestinal mucosa. These morphometric alterations are associated with the release of structural and functional cellular components into the feces and the blood stream creating measurable biomarkers to track this condition. Moreover, the identification of novel, immunometabolic biomarkers can provide dynamic and predictors of low-grade chronic inflammation, but also provide indicators of successful nutritional or feed additive intervention strategies. The objective of this paper is to review the mechanisms of low-grade inflammation, its effects on animal production and sustainability, and the biomarkers that could provide early diagnosis of this process and support studies of useful interventional strategies." @default.
- W4308443752 created "2022-11-11" @default.
- W4308443752 creator A5024624204 @default.
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- W4308443752 creator A5028458281 @default.
- W4308443752 creator A5046587210 @default.
- W4308443752 creator A5057420131 @default.
- W4308443752 date "2022-11-04" @default.
- W4308443752 modified "2023-10-18" @default.
- W4308443752 title "Morphological Assessment and Biomarkers of Low-Grade, Chronic Intestinal Inflammation in Production Animals" @default.
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