Matches in SemOpenAlex for { <https://semopenalex.org/work/W4308448082> ?p ?o ?g. }
- W4308448082 abstract "Escherichia coli pathogenic variants (pathovars) are generally characterized by defined virulence traits and are susceptible to the evolution of hybridized identities due to the considerable plasticity of the E. coli genome. We have isolated a strain from a purified diet intended for research animals that further demonstrates the ability of E. coli to acquire novel genetic elements leading potentially to emergent new pathovars. Utilizing next generation sequencing to obtain a whole genome profile, we report an atypical strain of E. coli, EcoFA807-17, possessing a tetrathionate reductase (ttr) operon, which enables the utilization of tetrathionate as an electron acceptor, thus facilitating respiration in anaerobic environments such as the mammalian gut. The ttr operon is a potent virulence factor for several enteric pathogens, most prominently Salmonella enterica. However, the presence of chromosomally integrated tetrathionate reductase genes does not appear to have been previously reported in wild-type E. coli or Shigella. Accordingly, it is possible that the appearance of this virulence factor may signal the evolution of new mechanisms of pathogenicity in E. coli and Shigella and may potentially alter the effectiveness of existing assays using tetrathionate reductase as a unique marker for the detection of Salmonella enterica." @default.
- W4308448082 created "2022-11-12" @default.
- W4308448082 creator A5017763822 @default.
- W4308448082 creator A5035992081 @default.
- W4308448082 creator A5041313387 @default.
- W4308448082 creator A5068290727 @default.
- W4308448082 date "2022-11-06" @default.
- W4308448082 modified "2023-09-26" @default.
- W4308448082 title "The emergence of the tetrathionate reductase operon in the <i>Escherichia coli/Shigella</i> pan‐genome" @default.
- W4308448082 cites W1603791918 @default.
- W4308448082 cites W1607161276 @default.
- W4308448082 cites W1625654822 @default.
- W4308448082 cites W1716847341 @default.
- W4308448082 cites W1895970128 @default.
- W4308448082 cites W1907660394 @default.
- W4308448082 cites W1909050135 @default.
- W4308448082 cites W1977535648 @default.
- W4308448082 cites W1980042804 @default.
- W4308448082 cites W1984159720 @default.
- W4308448082 cites W1984706424 @default.
- W4308448082 cites W1985783302 @default.
- W4308448082 cites W2000483782 @default.
- W4308448082 cites W2010928292 @default.
- W4308448082 cites W2019993991 @default.
- W4308448082 cites W2025410674 @default.
- W4308448082 cites W2037702752 @default.
- W4308448082 cites W2048045783 @default.
- W4308448082 cites W2063756105 @default.
- W4308448082 cites W2077425680 @default.
- W4308448082 cites W2096093282 @default.
- W4308448082 cites W2101563524 @default.
- W4308448082 cites W2103391211 @default.
- W4308448082 cites W2105517716 @default.
- W4308448082 cites W2112160436 @default.
- W4308448082 cites W2123349167 @default.
- W4308448082 cites W2129159701 @default.
- W4308448082 cites W2135780060 @default.
- W4308448082 cites W2136034879 @default.
- W4308448082 cites W2144535408 @default.
- W4308448082 cites W2149930533 @default.
- W4308448082 cites W2151379731 @default.
- W4308448082 cites W2155239768 @default.
- W4308448082 cites W2167591869 @default.
- W4308448082 cites W2168771543 @default.
- W4308448082 cites W2170986953 @default.
- W4308448082 cites W2261683559 @default.
- W4308448082 cites W2525247659 @default.
- W4308448082 cites W2559133556 @default.
- W4308448082 cites W2624190329 @default.
- W4308448082 cites W2626858578 @default.
- W4308448082 cites W2741474637 @default.
- W4308448082 cites W2745413354 @default.
- W4308448082 cites W2753242746 @default.
- W4308448082 cites W2758705200 @default.
- W4308448082 cites W2765547181 @default.
- W4308448082 cites W2768967257 @default.
- W4308448082 cites W3001925819 @default.
- W4308448082 cites W4231164717 @default.
- W4308448082 cites W825685433 @default.
- W4308448082 doi "https://doi.org/10.1002/mbo3.1333" @default.
- W4308448082 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36479628" @default.
- W4308448082 hasPublicationYear "2022" @default.
- W4308448082 type Work @default.
- W4308448082 citedByCount "0" @default.
- W4308448082 crossrefType "journal-article" @default.
- W4308448082 hasAuthorship W4308448082A5017763822 @default.
- W4308448082 hasAuthorship W4308448082A5035992081 @default.
- W4308448082 hasAuthorship W4308448082A5041313387 @default.
- W4308448082 hasAuthorship W4308448082A5068290727 @default.
- W4308448082 hasBestOaLocation W43084480821 @default.
- W4308448082 hasConcept C104317684 @default.
- W4308448082 hasConcept C141231307 @default.
- W4308448082 hasConcept C203075996 @default.
- W4308448082 hasConcept C22744801 @default.
- W4308448082 hasConcept C2776062316 @default.
- W4308448082 hasConcept C2776986154 @default.
- W4308448082 hasConcept C2779607309 @default.
- W4308448082 hasConcept C2781065037 @default.
- W4308448082 hasConcept C523546767 @default.
- W4308448082 hasConcept C54355233 @default.
- W4308448082 hasConcept C547475151 @default.
- W4308448082 hasConcept C60987743 @default.
- W4308448082 hasConcept C86803240 @default.
- W4308448082 hasConcept C89423630 @default.
- W4308448082 hasConceptScore W4308448082C104317684 @default.
- W4308448082 hasConceptScore W4308448082C141231307 @default.
- W4308448082 hasConceptScore W4308448082C203075996 @default.
- W4308448082 hasConceptScore W4308448082C22744801 @default.
- W4308448082 hasConceptScore W4308448082C2776062316 @default.
- W4308448082 hasConceptScore W4308448082C2776986154 @default.
- W4308448082 hasConceptScore W4308448082C2779607309 @default.
- W4308448082 hasConceptScore W4308448082C2781065037 @default.
- W4308448082 hasConceptScore W4308448082C523546767 @default.
- W4308448082 hasConceptScore W4308448082C54355233 @default.
- W4308448082 hasConceptScore W4308448082C547475151 @default.
- W4308448082 hasConceptScore W4308448082C60987743 @default.
- W4308448082 hasConceptScore W4308448082C86803240 @default.
- W4308448082 hasConceptScore W4308448082C89423630 @default.
- W4308448082 hasIssue "6" @default.
- W4308448082 hasLocation W43084480821 @default.