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- W4308461132 endingPage "109507" @default.
- W4308461132 startingPage "109507" @default.
- W4308461132 abstract "The endocrine system modulates several physiological functions such as development and metamorphosis in insects. The normal growth and development of insects is interfered with insect growth regulators (IGRs), which act as mimics of insect hormones like juvenile hormone (JH) and ecdysone hormone. The effects of JH and its analogs on systemic immunity have been identified. However the effect of these compounds on local gut immunity is largely unknown. In this study, the effects of JH analog fenoxycarb on the local gut immunity of Helicoverpa armigera, gut bacteria population, and their role in the pathogenicity of Bacillus thuringiensis (Bt) were analyzed. The results showed that feeding fenoxycarb causes a decrease in the transcription level of IMD (Relish and PGPR-LC), ROS (DUOX and SOD) related genes and antimicrobial peptides (AMPs), followed by an overpopulation of gut bacteria. The fenoxycarb-treated larvae showed higher susceptibility to Bt compared to the control larvae. Overall, these findings collectively suggest that JH analog affects local gut immunity and gut bacteria titer." @default.
- W4308461132 created "2022-11-12" @default.
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- W4308461132 creator A5035530679 @default.
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- W4308461132 date "2023-02-01" @default.
- W4308461132 modified "2023-10-17" @default.
- W4308461132 title "The endocrine disruptor, fenoxycarb modulates gut immunity and gut bacteria titer in the cotton bollworm, Helicoverpa armigera" @default.
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- W4308461132 doi "https://doi.org/10.1016/j.cbpc.2022.109507" @default.
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