FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4308462137> ?p ?o ?g. }

• W4308462137 endingPage "160022" @default.
• W4308462137 startingPage "160022" @default.
• W4308462137 abstract "Antibiotic resistance (AR) development in natural water bodies is a significant source of concern. Macrolide antibiotics in particular have been identified as pollutants of concern for AR development throughout the literature, as well as by state and international authorities. This study utilises a probabilistic model to examine the risk of AR development arising from human-use macrolide residues, utilising administration rates from Ireland as a case study. Stages modelled included level of administration, excretion, degradation in wastewater, removal in wastewater treatment, assuming conventional activated sludge (CAS) treatment, and dilution. Release estimates per day, as well as risk quotient values for antibiotic resistance development and ecological impact, are generated for erythromycin, clarithromycin, and azithromycin. In the modelled scenario in which conventional activated sludge treatment is utilised in wastewater treatment, this model ranks risk of resistance development for each antibiotic in the order clarithromycin > azithromycin > erythromycin, with mean risk quotient values of 0.50, 0.34 and 0.12, respectively. A membrane bioreactor scenario was also modelled, which reduced risk quotient values for all three macrolides by at least 50 %. Risk of ecological impact for each antibiotic was also examined, by comparing environmental concentrations predicted to safety limits based on toxicity data for cyanobacteria and other organisms from the literature, with azithromycin being identified as the macrolide of highest risk. This study compares and quantifies the risk of resistance development and ecological impact for a high-risk antibiotic group in the Irish context, and demonstrates the potential for risk reduction achieved by adoption of alternative (e.g. membrane bioreactor) technology." @default.
• W4308462137 created "2022-11-12" @default.
• W4308462137 creator A5031089093 @default.
• W4308462137 creator A5039240510 @default.
• W4308462137 creator A5041583476 @default.
• W4308462137 creator A5064681826 @default.
• W4308462137 date "2023-02-01" @default.
• W4308462137 modified "2023-10-04" @default.
• W4308462137 title "Risk ranking of macrolide antibiotics – Release levels, resistance formation potential and ecological risk" @default.
• W4308462137 cites W1567273855 @default.
• W4308462137 cites W1971724498 @default.
• W4308462137 cites W1978877574 @default.
• W4308462137 cites W1983747391 @default.
• W4308462137 cites W1996757989 @default.
• W4308462137 cites W1996886118 @default.
• W4308462137 cites W2004033157 @default.
• W4308462137 cites W2009727149 @default.
• W4308462137 cites W2013731232 @default.
• W4308462137 cites W2029593210 @default.
• W4308462137 cites W2035944811 @default.
• W4308462137 cites W2039108567 @default.
• W4308462137 cites W2040812961 @default.
• W4308462137 cites W2043639070 @default.
• W4308462137 cites W2045710757 @default.
• W4308462137 cites W2045935930 @default.
• W4308462137 cites W2053505865 @default.
• W4308462137 cites W2060024648 @default.
• W4308462137 cites W2064839074 @default.
• W4308462137 cites W2067300730 @default.
• W4308462137 cites W2073847280 @default.
• W4308462137 cites W2083512130 @default.
• W4308462137 cites W2087610336 @default.
• W4308462137 cites W2094410906 @default.
• W4308462137 cites W2100005279 @default.
• W4308462137 cites W2109207923 @default.
• W4308462137 cites W2125921606 @default.
• W4308462137 cites W2137691239 @default.
• W4308462137 cites W2140828410 @default.
• W4308462137 cites W2197156841 @default.
• W4308462137 cites W2236556070 @default.
• W4308462137 cites W2329698365 @default.
• W4308462137 cites W2513449905 @default.
• W4308462137 cites W2586609287 @default.
• W4308462137 cites W2751296860 @default.
• W4308462137 cites W2762002141 @default.
• W4308462137 cites W2792025977 @default.
• W4308462137 cites W2793460581 @default.
• W4308462137 cites W2896659362 @default.
• W4308462137 cites W2914752743 @default.
• W4308462137 cites W2920967421 @default.
• W4308462137 cites W2936015774 @default.
• W4308462137 cites W2938929754 @default.
• W4308462137 cites W2949371513 @default.
• W4308462137 cites W2952433266 @default.
• W4308462137 cites W2957922443 @default.
• W4308462137 cites W2972244201 @default.
• W4308462137 cites W3019611433 @default.
• W4308462137 cites W3045035217 @default.
• W4308462137 cites W3093312808 @default.
• W4308462137 cites W3127410554 @default.
• W4308462137 cites W3130074412 @default.
• W4308462137 cites W3153058901 @default.
• W4308462137 cites W3160313721 @default.
• W4308462137 cites W3183666413 @default.
• W4308462137 cites W4213351877 @default.
• W4308462137 doi "https://doi.org/10.1016/j.scitotenv.2022.160022" @default.
• W4308462137 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36368382" @default.
• W4308462137 hasPublicationYear "2023" @default.
• W4308462137 type Work @default.
• W4308462137 citedByCount "0" @default.
• W4308462137 crossrefType "journal-article" @default.
• W4308462137 hasAuthorship W4308462137A5031089093 @default.
• W4308462137 hasAuthorship W4308462137A5039240510 @default.
• W4308462137 hasAuthorship W4308462137A5041583476 @default.
• W4308462137 hasAuthorship W4308462137A5064681826 @default.
• W4308462137 hasConcept C112930515 @default.
• W4308462137 hasConcept C12174686 @default.
• W4308462137 hasConcept C151730666 @default.
• W4308462137 hasConcept C18903297 @default.
• W4308462137 hasConcept C2776962512 @default.
• W4308462137 hasConcept C2778155338 @default.
• W4308462137 hasConcept C2778907293 @default.
• W4308462137 hasConcept C2779343474 @default.
• W4308462137 hasConcept C2780206985 @default.
• W4308462137 hasConcept C38652104 @default.
• W4308462137 hasConcept C41008148 @default.
• W4308462137 hasConcept C501593827 @default.
• W4308462137 hasConcept C71924100 @default.
• W4308462137 hasConcept C86803240 @default.
• W4308462137 hasConcept C89423630 @default.
• W4308462137 hasConcept C94665300 @default.
• W4308462137 hasConceptScore W4308462137C112930515 @default.
• W4308462137 hasConceptScore W4308462137C12174686 @default.
• W4308462137 hasConceptScore W4308462137C151730666 @default.
• W4308462137 hasConceptScore W4308462137C18903297 @default.
• W4308462137 hasConceptScore W4308462137C2776962512 @default.
• W4308462137 hasConceptScore W4308462137C2778155338 @default.
• W4308462137 hasConceptScore W4308462137C2778907293 @default.

• next