Matches in SemOpenAlex for { <https://semopenalex.org/work/W4308487614> ?p ?o ?g. }
- W4308487614 endingPage "368" @default.
- W4308487614 startingPage "359" @default.
- W4308487614 abstract "Reducing consumption of sugar-sweetened beverages (SSBs) is a global public health priority because of their limited nutritional value and associations with increased risk of obesity and metabolic diseases. Gut microbiota-related metabolites emerged as quintessential effectors that may mediate impacts of dietary exposures on the modulation of host commensal microbiome and physiological status.This study assessed the associations among SSBs, circulating microbial metabolites, and gut microbiota-host co-metabolites, as well as metabolic health outcomes in young Chinese adults (n = 86), from the Carbohydrate Alternatives and Metabolic Phenotypes study in Shaanxi Province. Five principal component analysis-derived beverage drinking patterns were determined on self-reported SSB intakes, which were to a varying degree associated with 143 plasma levels of gut microbiota-related metabolites profiled by untargeted metabolomics. Moreover, carbonated beverages, fruit juice, energy drinks, and bubble tea exhibited positive associations with obesity-related markers and blood lipids, which were further validated in an independent cohort of 16,851 participants from the Regional Ethnic Cohort Study in Northwest China in Shaanxi Province. In contrast, presweetened coffee was negatively associated with the obesity-related traits. A total of 79 metabolites were associated with both SSBs and metabolic markers, particularly obesity markers. Pathway enrichment analysis identified the branched-chain amino acid catabolism and aminoacyl-tRNA biosynthesis as linking SSB intake with metabolic health outcomes.Our findings demonstrate the associations between habitual intakes of SSBs and several metabolic markers relevant to noncommunicable diseases, and highlight the critical involvement of gut microbiota-related metabolites in mediating such associations." @default.
- W4308487614 created "2022-11-12" @default.
- W4308487614 creator A5006783423 @default.
- W4308487614 creator A5009194583 @default.
- W4308487614 creator A5020631234 @default.
- W4308487614 creator A5021687717 @default.
- W4308487614 creator A5024878311 @default.
- W4308487614 creator A5029770334 @default.
- W4308487614 creator A5054161527 @default.
- W4308487614 creator A5057093808 @default.
- W4308487614 creator A5057821547 @default.
- W4308487614 creator A5076139079 @default.
- W4308487614 creator A5078017584 @default.
- W4308487614 creator A5080316703 @default.
- W4308487614 creator A5080653475 @default.
- W4308487614 creator A5086561170 @default.
- W4308487614 date "2023-02-01" @default.
- W4308487614 modified "2023-10-14" @default.
- W4308487614 title "Habitual intakes of sugar-sweetened beverages associated with gut microbiota-related metabolites and metabolic health outcomes in young Chinese adults" @default.
- W4308487614 cites W1966598590 @default.
- W4308487614 cites W2002364623 @default.
- W4308487614 cites W2004199309 @default.
- W4308487614 cites W2005801109 @default.
- W4308487614 cites W2011226180 @default.
- W4308487614 cites W2028719601 @default.
- W4308487614 cites W2036264510 @default.
- W4308487614 cites W2106539706 @default.
- W4308487614 cites W2142083023 @default.
- W4308487614 cites W2162323969 @default.
- W4308487614 cites W2204741364 @default.
- W4308487614 cites W2324901269 @default.
- W4308487614 cites W2335393395 @default.
- W4308487614 cites W2397334001 @default.
- W4308487614 cites W2468194934 @default.
- W4308487614 cites W2604249580 @default.
- W4308487614 cites W2625861313 @default.
- W4308487614 cites W2659924278 @default.
- W4308487614 cites W2735408048 @default.
- W4308487614 cites W2735584664 @default.
- W4308487614 cites W2790486637 @default.
- W4308487614 cites W2855216278 @default.
- W4308487614 cites W2905292763 @default.
- W4308487614 cites W2913194098 @default.
- W4308487614 cites W2913606000 @default.
- W4308487614 cites W2915433988 @default.
- W4308487614 cites W2921460411 @default.
- W4308487614 cites W2948407755 @default.
- W4308487614 cites W2961102834 @default.
- W4308487614 cites W2975121145 @default.
- W4308487614 cites W2977008551 @default.
- W4308487614 cites W2978326608 @default.
- W4308487614 cites W2981527755 @default.
- W4308487614 cites W2986276979 @default.
- W4308487614 cites W2990997421 @default.
- W4308487614 cites W3012327742 @default.
- W4308487614 cites W3021801233 @default.
- W4308487614 cites W3033138470 @default.
- W4308487614 cites W3035567023 @default.
- W4308487614 cites W3044428548 @default.
- W4308487614 cites W3083934892 @default.
- W4308487614 cites W3087016701 @default.
- W4308487614 cites W3088203083 @default.
- W4308487614 cites W3089808186 @default.
- W4308487614 cites W3092070202 @default.
- W4308487614 cites W3092548217 @default.
- W4308487614 cites W3092617160 @default.
- W4308487614 cites W3093868490 @default.
- W4308487614 cites W3097808327 @default.
- W4308487614 cites W3106931136 @default.
- W4308487614 cites W3107083588 @default.
- W4308487614 cites W3109895489 @default.
- W4308487614 cites W3117428187 @default.
- W4308487614 cites W3124801347 @default.
- W4308487614 cites W3131849960 @default.
- W4308487614 cites W3145021642 @default.
- W4308487614 cites W3147281519 @default.
- W4308487614 cites W3206365861 @default.
- W4308487614 cites W4221033726 @default.
- W4308487614 cites W635049068 @default.
- W4308487614 doi "https://doi.org/10.1016/j.numecd.2022.10.016" @default.
- W4308487614 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36577637" @default.
- W4308487614 hasPublicationYear "2023" @default.
- W4308487614 type Work @default.
- W4308487614 citedByCount "5" @default.
- W4308487614 countsByYear W43084876142023 @default.
- W4308487614 crossrefType "journal-article" @default.
- W4308487614 hasAuthorship W4308487614A5006783423 @default.
- W4308487614 hasAuthorship W4308487614A5009194583 @default.
- W4308487614 hasAuthorship W4308487614A5020631234 @default.
- W4308487614 hasAuthorship W4308487614A5021687717 @default.
- W4308487614 hasAuthorship W4308487614A5024878311 @default.
- W4308487614 hasAuthorship W4308487614A5029770334 @default.
- W4308487614 hasAuthorship W4308487614A5054161527 @default.
- W4308487614 hasAuthorship W4308487614A5057093808 @default.
- W4308487614 hasAuthorship W4308487614A5057821547 @default.
- W4308487614 hasAuthorship W4308487614A5076139079 @default.
- W4308487614 hasAuthorship W4308487614A5078017584 @default.
- W4308487614 hasAuthorship W4308487614A5080316703 @default.