Matches in SemOpenAlex for { <https://semopenalex.org/work/W4308493722> ?p ?o ?g. }
- W4308493722 abstract "There are several bacteria called superbugs that are resistant to multiple antibiotics which can be life threatening specially for critically ill and hospitalized patients. This article provides up-to-date treatment strategies employed against some major superbugs, like methicillin-resistant Staphylococcus aureus, carbapenem-resistant Enterobacteriaceae, vancomycin-resistant Enterococcus, multidrug-resistant Pseudomonas aeruginosa, and multidrug-resistant Escherichia coli. The pathogen-directed therapeutics decrease the toxicity of bacteria by altering their virulence factors by specific processes. On the other hand, the host-directed therapeutics limits these superbugs by modulating immune cells, enhancing host cell functions, and modifying disease pathology. Several new antibiotics against the global priority superbugs are coming to the market or are in the clinical development phase. Medicinal plants possessing potent secondary metabolites can play a key role in the treatment against these superbugs. Nanotechnology has also emerged as a promising option for combatting them. There is urgent need to continuously figure out the best possible treatment strategy against these superbugs as resistance can also be developed against the new and upcoming antibiotics in future. Rational use of antibiotics and maintenance of proper hygiene must be practiced among patients." @default.
- W4308493722 created "2022-11-12" @default.
- W4308493722 creator A5027128907 @default.
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- W4308493722 creator A5063556803 @default.
- W4308493722 creator A5074623171 @default.
- W4308493722 creator A5079081054 @default.
- W4308493722 date "2022-11-03" @default.
- W4308493722 modified "2023-10-04" @default.
- W4308493722 title "Current Treatment Strategies Against Multidrug-Resistant Bacteria: A Review" @default.
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- W4308493722 doi "https://doi.org/10.1007/s00284-022-03061-7" @default.
- W4308493722 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36329256" @default.
- W4308493722 hasPublicationYear "2022" @default.