FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4308494679> ?p ?o ?g. }

• W4308494679 endingPage "308" @default.
• W4308494679 startingPage "275" @default.
• W4308494679 abstract "There are approximately 260 known species in the genus Millettia, many of which are used in traditional medicine to treat human and other animal ailments in various parts of the world. Being in the Leguminosae (Fabaceae) family, Millettia species are rich sources of isoflavonoids. In the past three decades alone, several isoflavonoids originating from Millettia have been isolated, and their pharmacological activities have been evaluated against major diseases, such as cancer, inflammation, and diabetes. Despite such extensive research, no recent and comprehensive review of the phytochemistry and pharmacology of Millettia isoflavonoids is available. Furthermore, the structural diversity of isoflavonoids in Millettia species has rarely been reported. In this review, we comprehensively summarized the structural diversity of Millettia isoflavonoids, the methods used for their extraction and isolation protocols, and their pharmacological properties. According to the literature, 154 structurally diverse isoflavonoids were isolated and reported from the various tissues of nine well-known Millettia species. Prenylated isoflavonoids and rotenoids were the most dominant subclasses of isoflavonoids reported. Other subclasses of reported isoflavonoids include isoflavans, aglycone isoflavones, glycosylated isoflavones, geranylated isoflavonoids, phenylcoumarins, pterocarpans and coumaronochromenes. Although some isolated molecules showed promising pharmacological properties, such as anticancer, anti-inflammatory, estrogenic, and antibacterial activities, others remained untested. In general, this review highlights the potential of Millettia isoflavonoids and could improve their utilization in drug discovery and medicinal use processes.The online version contains supplementary material available at 10.1007/s11101-022-09845-w." @default.
• W4308494679 created "2022-11-12" @default.
• W4308494679 creator A5005248449 @default.
• W4308494679 creator A5087665758 @default.
• W4308494679 date "2022-11-03" @default.
• W4308494679 modified "2023-10-16" @default.
• W4308494679 title "Millettia isoflavonoids: a comprehensive review of structural diversity, extraction, isolation, and pharmacological properties" @default.
• W4308494679 cites W109327108 @default.
• W4308494679 cites W123521375 @default.
• W4308494679 cites W1581999513 @default.
• W4308494679 cites W1612982626 @default.
• W4308494679 cites W1965055742 @default.
• W4308494679 cites W1966053131 @default.
• W4308494679 cites W1967077671 @default.
• W4308494679 cites W1970880555 @default.
• W4308494679 cites W1972943926 @default.
• W4308494679 cites W1985575794 @default.
• W4308494679 cites W1998851516 @default.
• W4308494679 cites W2000879252 @default.
• W4308494679 cites W2002788713 @default.
• W4308494679 cites W2008272634 @default.
• W4308494679 cites W2010551599 @default.
• W4308494679 cites W2012153244 @default.
• W4308494679 cites W2028306092 @default.
• W4308494679 cites W2032206999 @default.
• W4308494679 cites W2036146410 @default.
• W4308494679 cites W2036276021 @default.
• W4308494679 cites W2037844373 @default.
• W4308494679 cites W2054686908 @default.
• W4308494679 cites W2056634831 @default.
• W4308494679 cites W2058547632 @default.
• W4308494679 cites W2061574660 @default.
• W4308494679 cites W2065599545 @default.
• W4308494679 cites W2066715924 @default.
• W4308494679 cites W2070021310 @default.
• W4308494679 cites W2071133887 @default.
• W4308494679 cites W2071419109 @default.
• W4308494679 cites W2072721238 @default.
• W4308494679 cites W2074551109 @default.
• W4308494679 cites W2075588585 @default.
• W4308494679 cites W2077048665 @default.
• W4308494679 cites W2082101467 @default.
• W4308494679 cites W2082201274 @default.
• W4308494679 cites W2087697581 @default.
• W4308494679 cites W2088231349 @default.
• W4308494679 cites W2090798687 @default.
• W4308494679 cites W2091853610 @default.
• W4308494679 cites W2092144605 @default.
• W4308494679 cites W2093700393 @default.
• W4308494679 cites W2100635196 @default.
• W4308494679 cites W2104897032 @default.
• W4308494679 cites W2105277692 @default.
• W4308494679 cites W2113712041 @default.
• W4308494679 cites W2115228747 @default.
• W4308494679 cites W2131856346 @default.
• W4308494679 cites W2133880260 @default.
• W4308494679 cites W2136649630 @default.
• W4308494679 cites W2150506013 @default.
• W4308494679 cites W2151056211 @default.
• W4308494679 cites W2151175503 @default.
• W4308494679 cites W2157121861 @default.
• W4308494679 cites W2165666776 @default.
• W4308494679 cites W2289118032 @default.
• W4308494679 cites W2289591944 @default.
• W4308494679 cites W2295540685 @default.
• W4308494679 cites W2327275778 @default.
• W4308494679 cites W2491755642 @default.
• W4308494679 cites W2502699492 @default.
• W4308494679 cites W2561159205 @default.
• W4308494679 cites W2583275798 @default.
• W4308494679 cites W2623472255 @default.
• W4308494679 cites W2770957301 @default.
• W4308494679 cites W2786571650 @default.
• W4308494679 cites W2793971745 @default.
• W4308494679 cites W2801463684 @default.
• W4308494679 cites W2883693532 @default.
• W4308494679 cites W2884641450 @default.
• W4308494679 cites W2887467319 @default.
• W4308494679 cites W2888686557 @default.
• W4308494679 cites W2894233472 @default.
• W4308494679 cites W2908841689 @default.
• W4308494679 cites W2910312371 @default.
• W4308494679 cites W2911577646 @default.
• W4308494679 cites W2924903716 @default.
• W4308494679 cites W2933732328 @default.
• W4308494679 cites W2950905829 @default.
• W4308494679 cites W2952991050 @default.
• W4308494679 cites W2964456700 @default.
• W4308494679 cites W2966918489 @default.
• W4308494679 cites W2967788503 @default.
• W4308494679 cites W2971540066 @default.
• W4308494679 cites W2979216405 @default.
• W4308494679 cites W2995318715 @default.
• W4308494679 cites W3004563230 @default.
• W4308494679 cites W3009678818 @default.
• W4308494679 cites W3014275589 @default.
• W4308494679 cites W3019662048 @default.
• W4308494679 cites W3035846281 @default.

• next