Matches in SemOpenAlex for { <https://semopenalex.org/work/W4308500623> ?p ?o ?g. }
- W4308500623 endingPage "101773" @default.
- W4308500623 startingPage "101773" @default.
- W4308500623 abstract "Emerging evidence suggests that the intestinal microbiota (IM) undergoes remodelling as we age, and this impacts the ageing trajectory and mortality in older adults. The aim was to investigate IM diversity differences between frail and non-frail older adults by meta-analysing previous studies. The protocol of this systematic review with meta-analysis was registered on PROSPERO (CRD42021276733). We searched for studies comparing IM diversity of frail and non-frail older adults indexed on PubMed, Embase, Cochrane, and Web of Science in November 2021. We included 11 studies with 1239 participants, of which 340 were meta-analysed. Frailty was defined by a variety of criteria (i.e. Fried Scale, European Consensus on Sarcopenia). There were no differences in the meta-analyses between the frail and non-frail groups for species richness index (SMD = −0.147; 95% CI = −0.394, 0.100; p = 0.243) and species diversity index (SMD = −0.033; 95% CI = −0.315, 0.250; p = 0.820). However, we identified almost 50 differences between frail and non-frail within the relative abundance of bacteria phyla, families, genera, and species in the primary studies. The evidence to prove that there are differences between frail and non-frail IM diversity by meta-analysis is still lacking. The present results suggest that further investigation into the role of specific bacteria, their function, and their influence on the physiopathology of frailty is needed." @default.
- W4308500623 created "2022-11-12" @default.
- W4308500623 creator A5011620477 @default.
- W4308500623 creator A5019810894 @default.
- W4308500623 creator A5083267482 @default.
- W4308500623 creator A5087838249 @default.
- W4308500623 creator A5091356527 @default.
- W4308500623 date "2022-12-01" @default.
- W4308500623 modified "2023-10-16" @default.
- W4308500623 title "Comparison between frail and non-frail older adults’ gut microbiota: A systematic review and meta-analysis" @default.
- W4308500623 cites W1537972189 @default.
- W4308500623 cites W2016952802 @default.
- W4308500623 cites W2019419945 @default.
- W4308500623 cites W2019427304 @default.
- W4308500623 cites W2039196160 @default.
- W4308500623 cites W2041751047 @default.
- W4308500623 cites W2049072897 @default.
- W4308500623 cites W2055057012 @default.
- W4308500623 cites W2064512594 @default.
- W4308500623 cites W2088170171 @default.
- W4308500623 cites W2102902846 @default.
- W4308500623 cites W2103108588 @default.
- W4308500623 cites W2104890139 @default.
- W4308500623 cites W2113552312 @default.
- W4308500623 cites W2129130754 @default.
- W4308500623 cites W2131987394 @default.
- W4308500623 cites W2132209276 @default.
- W4308500623 cites W2141125135 @default.
- W4308500623 cites W2141691140 @default.
- W4308500623 cites W2144582237 @default.
- W4308500623 cites W2155770880 @default.
- W4308500623 cites W2156791190 @default.
- W4308500623 cites W2159982881 @default.
- W4308500623 cites W2161754779 @default.
- W4308500623 cites W2161915756 @default.
- W4308500623 cites W2163940893 @default.
- W4308500623 cites W2164059021 @default.
- W4308500623 cites W2164186760 @default.
- W4308500623 cites W2166016360 @default.
- W4308500623 cites W2171060095 @default.
- W4308500623 cites W2263333073 @default.
- W4308500623 cites W2271035348 @default.
- W4308500623 cites W2285022550 @default.
- W4308500623 cites W2371807656 @default.
- W4308500623 cites W2381299150 @default.
- W4308500623 cites W2385413224 @default.
- W4308500623 cites W241590697 @default.
- W4308500623 cites W2416662732 @default.
- W4308500623 cites W2462759270 @default.
- W4308500623 cites W2518202212 @default.
- W4308500623 cites W2550084345 @default.
- W4308500623 cites W2560438049 @default.
- W4308500623 cites W2587402341 @default.
- W4308500623 cites W2602243360 @default.
- W4308500623 cites W2607434574 @default.
- W4308500623 cites W2755653983 @default.
- W4308500623 cites W2764276208 @default.
- W4308500623 cites W2765279273 @default.
- W4308500623 cites W2770074712 @default.
- W4308500623 cites W2793290204 @default.
- W4308500623 cites W2811395700 @default.
- W4308500623 cites W2889234747 @default.
- W4308500623 cites W2893816498 @default.
- W4308500623 cites W2897513125 @default.
- W4308500623 cites W2911772760 @default.
- W4308500623 cites W2912861289 @default.
- W4308500623 cites W2919947473 @default.
- W4308500623 cites W2951344089 @default.
- W4308500623 cites W2959728234 @default.
- W4308500623 cites W2979434443 @default.
- W4308500623 cites W2981465790 @default.
- W4308500623 cites W3004747937 @default.
- W4308500623 cites W3005437800 @default.
- W4308500623 cites W3026296114 @default.
- W4308500623 cites W3035602929 @default.
- W4308500623 cites W3138695602 @default.
- W4308500623 cites W3139169691 @default.
- W4308500623 cites W4294215472 @default.
- W4308500623 doi "https://doi.org/10.1016/j.arr.2022.101773" @default.
- W4308500623 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36349647" @default.
- W4308500623 hasPublicationYear "2022" @default.
- W4308500623 type Work @default.
- W4308500623 citedByCount "3" @default.
- W4308500623 countsByYear W43085006232022 @default.
- W4308500623 countsByYear W43085006232023 @default.
- W4308500623 crossrefType "journal-article" @default.
- W4308500623 hasAuthorship W4308500623A5011620477 @default.
- W4308500623 hasAuthorship W4308500623A5019810894 @default.
- W4308500623 hasAuthorship W4308500623A5083267482 @default.
- W4308500623 hasAuthorship W4308500623A5087838249 @default.
- W4308500623 hasAuthorship W4308500623A5091356527 @default.
- W4308500623 hasConcept C126322002 @default.
- W4308500623 hasConcept C189708586 @default.
- W4308500623 hasConcept C2779473830 @default.
- W4308500623 hasConcept C500499127 @default.
- W4308500623 hasConcept C55493867 @default.
- W4308500623 hasConcept C71924100 @default.
- W4308500623 hasConcept C74909509 @default.