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- W4308500897 abstract "Abstract Tinospora crispa (L.) Hook. f. & Thomson (Menispermaceae) is a plant indigenous to Africa and South-East Asia. It is widely used in ethnomedicine to alleviate various diseases including hypertension, diabetes, rheumatism, jaundice, inflammation, fever, fractures, scabies, and urinary disorders. A total of 167 phytoconstituents, belonging to 12 different chemical categories, including alkaloids, flavonoids, terpenoids, and phenolic compounds have thus far been isolated from various parts of T. crispa. Numerous in vitro and in vivo investigations have already established the antidiabetic, anticancer, antiparasitic, antimicrobial, immunomodulatory, hepatoprotective, analgesic, antipyretic, antihyperuricemic, and pesticidal activity of this plant, as well as its effects on the cardiac and the central nervous system. Most pharmacological investigations to date have been carried out on plant extracts and fractions. The exact identity of the phytoconstituents responsible for the observed biological effects and their mode of action at the molecular level are yet to be ascertained. Toxicological studies have demonstrated that T. crispa is relatively safe, although dose-dependent hepatotoxicity is a concern at high doses. This review presents a comprehensive update and analysis on studies related to the ethnomedicinal uses, phytochemistry, pharmacological activity and toxicological profile of T. crispa . It provides some critical insights into the current scientific knowledge on this plant and its future potential in pharmaceutical research." @default.
- W4308500897 created "2022-11-12" @default.
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- W4308500897 creator A5044121358 @default.
- W4308500897 creator A5064442471 @default.
- W4308500897 date "2022-11-03" @default.
- W4308500897 modified "2023-10-18" @default.
- W4308500897 title "An updated and comprehensive review on the ethnomedicinal uses, phytochemistry, pharmacological activity and toxicological profile of Tinospora crispa (L.) Hook. f. & Thomson" @default.
- W4308500897 cites W1092130609 @default.
- W4308500897 cites W1526724018 @default.
- W4308500897 cites W1561645905 @default.
- W4308500897 cites W1718201877 @default.
- W4308500897 cites W1748788205 @default.
- W4308500897 cites W1883644090 @default.
- W4308500897 cites W1933696030 @default.
- W4308500897 cites W1945288046 @default.
- W4308500897 cites W1964170934 @default.
- W4308500897 cites W1968611254 @default.
- W4308500897 cites W1970585518 @default.
- W4308500897 cites W1971001968 @default.
- W4308500897 cites W1971088432 @default.
- W4308500897 cites W1978745384 @default.
- W4308500897 cites W1984171643 @default.
- W4308500897 cites W1984653518 @default.
- W4308500897 cites W1992445603 @default.
- W4308500897 cites W1992522914 @default.
- W4308500897 cites W1996606857 @default.
- W4308500897 cites W2004300612 @default.
- W4308500897 cites W2005362478 @default.
- W4308500897 cites W2013623989 @default.
- W4308500897 cites W2021383855 @default.
- W4308500897 cites W2021476621 @default.
- W4308500897 cites W2025400218 @default.
- W4308500897 cites W2028003944 @default.
- W4308500897 cites W2038893561 @default.
- W4308500897 cites W2045562324 @default.
- W4308500897 cites W2045880005 @default.
- W4308500897 cites W2046904276 @default.
- W4308500897 cites W2052374099 @default.
- W4308500897 cites W2054808599 @default.
- W4308500897 cites W2063642666 @default.
- W4308500897 cites W2064558702 @default.
- W4308500897 cites W2073538726 @default.
- W4308500897 cites W2075782116 @default.
- W4308500897 cites W2077670188 @default.
- W4308500897 cites W2082192610 @default.
- W4308500897 cites W2083415013 @default.
- W4308500897 cites W2109606842 @default.
- W4308500897 cites W2110411977 @default.
- W4308500897 cites W2110945615 @default.
- W4308500897 cites W2114132311 @default.
- W4308500897 cites W2122076151 @default.
- W4308500897 cites W2125174657 @default.
- W4308500897 cites W2127713036 @default.
- W4308500897 cites W2132013574 @default.
- W4308500897 cites W2145272279 @default.
- W4308500897 cites W2147004652 @default.
- W4308500897 cites W2161426970 @default.
- W4308500897 cites W2163831086 @default.
- W4308500897 cites W2164969457 @default.
- W4308500897 cites W2184199513 @default.
- W4308500897 cites W2188432610 @default.
- W4308500897 cites W2226470635 @default.
- W4308500897 cites W2245319722 @default.
- W4308500897 cites W2260315791 @default.
- W4308500897 cites W2269714760 @default.
- W4308500897 cites W2281879812 @default.
- W4308500897 cites W2294905164 @default.
- W4308500897 cites W2313093052 @default.
- W4308500897 cites W2329004940 @default.
- W4308500897 cites W2334708485 @default.
- W4308500897 cites W237655112 @default.
- W4308500897 cites W2407011740 @default.
- W4308500897 cites W2422867283 @default.
- W4308500897 cites W2510793065 @default.
- W4308500897 cites W2533720821 @default.
- W4308500897 cites W2537846521 @default.
- W4308500897 cites W2558827206 @default.
- W4308500897 cites W2560339187 @default.
- W4308500897 cites W2564414481 @default.
- W4308500897 cites W2574420447 @default.
- W4308500897 cites W2616284911 @default.
- W4308500897 cites W2619062478 @default.
- W4308500897 cites W2626728499 @default.
- W4308500897 cites W2727390739 @default.
- W4308500897 cites W2737733641 @default.
- W4308500897 cites W2751568703 @default.
- W4308500897 cites W2759298922 @default.
- W4308500897 cites W2793943033 @default.
- W4308500897 cites W2799373941 @default.
- W4308500897 cites W2799536443 @default.
- W4308500897 cites W2800090572 @default.
- W4308500897 cites W2805736579 @default.
- W4308500897 cites W2808129153 @default.