Matches in SemOpenAlex for { <https://semopenalex.org/work/W4308505719> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W4308505719 abstract "Fetal growth restriction (FGR) is a prevalent pregnancy condition characterised by failure of the fetus to reach its genetically predetermined growth potential. We explore the application of model fitting techniques, linear regression machine learning models, deep learning regression, and Haralick textured features from multi-contrast MRI for multi-fetal organ analysis of FGR. We employed T2 relaxometry and diffusion-weighted MRI datasets (using a combined T2-diffusion scan) for 12 normally grown and 12 FGR gestational age (GA) matched pregnancies. We applied the Intravoxel Incoherent Motion Model and novel multi-compartment models for MRI fetal analysis, which exhibit potential to provide a multi-organ FGR assessment, overcoming the limitations of empirical indicators - such as abnormal artery Doppler findings - to evaluate placental dysfunction. The placenta and fetal liver presented key differentiators between FGR and normal controls (decreased perfusion, abnormal fetal blood motion and reduced fetal blood oxygenation. This may be associated with the preferential shunting of the fetal blood towards the fetal brain. These features were further explored to determine their role in assessing FGR severity, by employing simple machine learning models to predict FGR diagnosis (100% accuracy in test data, n=5), GA at delivery, time from MRI scan to delivery, and baby weight. Moreover, we explored the use of deep learning to regress the latter three variables. Image texture analysis of the fetal organs demonstrated prominent textural variations in the placental perfusion fractions maps between the groups (p$<$0.0009), and spatial differences in the incoherent fetal capillary blood motion in the liver (p$<$0.009). This research serves as a proof-of-concept, investigating the effect of FGR on fetal organs." @default.
- W4308505719 created "2022-11-12" @default.
- W4308505719 creator A5024172356 @default.
- W4308505719 creator A5027548526 @default.
- W4308505719 creator A5031742600 @default.
- W4308505719 creator A5035099926 @default.
- W4308505719 creator A5048630864 @default.
- W4308505719 creator A5055496507 @default.
- W4308505719 creator A5060751261 @default.
- W4308505719 creator A5069531417 @default.
- W4308505719 creator A5078162248 @default.
- W4308505719 creator A5082106258 @default.
- W4308505719 creator A5087513517 @default.
- W4308505719 date "2022-11-01" @default.
- W4308505719 modified "2023-09-23" @default.
- W4308505719 title "PIPPI2021: An Approach to Automated Diagnosis and Texture Analysis of the Fetal Liver & Placenta in Fetal Growth Restriction" @default.
- W4308505719 doi "https://doi.org/10.48550/arxiv.2211.02639" @default.
- W4308505719 hasPublicationYear "2022" @default.
- W4308505719 type Work @default.
- W4308505719 citedByCount "0" @default.
- W4308505719 crossrefType "posted-content" @default.
- W4308505719 hasAuthorship W4308505719A5024172356 @default.
- W4308505719 hasAuthorship W4308505719A5027548526 @default.
- W4308505719 hasAuthorship W4308505719A5031742600 @default.
- W4308505719 hasAuthorship W4308505719A5035099926 @default.
- W4308505719 hasAuthorship W4308505719A5048630864 @default.
- W4308505719 hasAuthorship W4308505719A5055496507 @default.
- W4308505719 hasAuthorship W4308505719A5060751261 @default.
- W4308505719 hasAuthorship W4308505719A5069531417 @default.
- W4308505719 hasAuthorship W4308505719A5078162248 @default.
- W4308505719 hasAuthorship W4308505719A5082106258 @default.
- W4308505719 hasAuthorship W4308505719A5087513517 @default.
- W4308505719 hasBestOaLocation W43085057191 @default.
- W4308505719 hasConcept C126322002 @default.
- W4308505719 hasConcept C126838900 @default.
- W4308505719 hasConcept C143409427 @default.
- W4308505719 hasConcept C149550507 @default.
- W4308505719 hasConcept C172680121 @default.
- W4308505719 hasConcept C2776953305 @default.
- W4308505719 hasConcept C2778376644 @default.
- W4308505719 hasConcept C2779234561 @default.
- W4308505719 hasConcept C54355233 @default.
- W4308505719 hasConcept C71924100 @default.
- W4308505719 hasConcept C82641631 @default.
- W4308505719 hasConcept C86803240 @default.
- W4308505719 hasConceptScore W4308505719C126322002 @default.
- W4308505719 hasConceptScore W4308505719C126838900 @default.
- W4308505719 hasConceptScore W4308505719C143409427 @default.
- W4308505719 hasConceptScore W4308505719C149550507 @default.
- W4308505719 hasConceptScore W4308505719C172680121 @default.
- W4308505719 hasConceptScore W4308505719C2776953305 @default.
- W4308505719 hasConceptScore W4308505719C2778376644 @default.
- W4308505719 hasConceptScore W4308505719C2779234561 @default.
- W4308505719 hasConceptScore W4308505719C54355233 @default.
- W4308505719 hasConceptScore W4308505719C71924100 @default.
- W4308505719 hasConceptScore W4308505719C82641631 @default.
- W4308505719 hasConceptScore W4308505719C86803240 @default.
- W4308505719 hasLocation W43085057191 @default.
- W4308505719 hasLocation W43085057192 @default.
- W4308505719 hasOpenAccess W4308505719 @default.
- W4308505719 hasPrimaryLocation W43085057191 @default.
- W4308505719 hasRelatedWork W1997526440 @default.
- W4308505719 hasRelatedWork W2090583597 @default.
- W4308505719 hasRelatedWork W2090875198 @default.
- W4308505719 hasRelatedWork W2308280914 @default.
- W4308505719 hasRelatedWork W2389974487 @default.
- W4308505719 hasRelatedWork W2412883775 @default.
- W4308505719 hasRelatedWork W2744623810 @default.
- W4308505719 hasRelatedWork W279682730 @default.
- W4308505719 hasRelatedWork W4235453249 @default.
- W4308505719 hasRelatedWork W4244773948 @default.
- W4308505719 isParatext "false" @default.
- W4308505719 isRetracted "false" @default.
- W4308505719 workType "article" @default.