Matches in SemOpenAlex for { <https://semopenalex.org/work/W4308506789> ?p ?o ?g. }
- W4308506789 endingPage "2408" @default.
- W4308506789 startingPage "2408" @default.
- W4308506789 abstract "(1) Background: Peripheral nerve injuries represent a major clinical challenge. If nerve ends retract, there is no spontaneous regeneration and grafts are required to proximate the nerve ends and give continuity to the nerve. (2) Methods: GDNF-loaded NPs were characterized physicochemically. For that, NPs stability at different pH's was assessed, and GDNF release was studied through ELISA. In vitro studies are performed with Schwann cells, and the NPs are labeled with fluorescein-5(6)-isothiocyanate for uptake experiments with SH-SY5Y neural cells. (3) Results: GDNF-loaded NPs are stable in physiological conditions, releasing GDNF in a two-step profile, which is beneficial for nerve repair. Cell viability is improved after 1 day of culture, and the uptake is near 99.97% after 3 days of incubation. (4) Conclusions: The present work shows the efficiency of using CMCht/PAMAM NPs as a GDNF-release system to act on peripheral nerve regeneration." @default.
- W4308506789 created "2022-11-12" @default.
- W4308506789 creator A5015408416 @default.
- W4308506789 creator A5019199655 @default.
- W4308506789 creator A5032813462 @default.
- W4308506789 creator A5041545765 @default.
- W4308506789 creator A5056935928 @default.
- W4308506789 creator A5081499203 @default.
- W4308506789 date "2022-11-08" @default.
- W4308506789 modified "2023-10-18" @default.
- W4308506789 title "Glial Cell Line-Derived Neurotrophic Factor-Loaded CMCht/PAMAM Dendrimer Nanoparticles for Peripheral Nerve Repair" @default.
- W4308506789 cites W1971208141 @default.
- W4308506789 cites W1975139117 @default.
- W4308506789 cites W1979028576 @default.
- W4308506789 cites W1985260236 @default.
- W4308506789 cites W2028716442 @default.
- W4308506789 cites W2036950867 @default.
- W4308506789 cites W2044476979 @default.
- W4308506789 cites W2051690712 @default.
- W4308506789 cites W2070588034 @default.
- W4308506789 cites W2071842958 @default.
- W4308506789 cites W2072210354 @default.
- W4308506789 cites W2076090817 @default.
- W4308506789 cites W2076215738 @default.
- W4308506789 cites W2081578489 @default.
- W4308506789 cites W2082180854 @default.
- W4308506789 cites W2107175951 @default.
- W4308506789 cites W2153595754 @default.
- W4308506789 cites W2222895718 @default.
- W4308506789 cites W223254852 @default.
- W4308506789 cites W2265591599 @default.
- W4308506789 cites W2320466312 @default.
- W4308506789 cites W2567071855 @default.
- W4308506789 cites W2583876620 @default.
- W4308506789 cites W2587134196 @default.
- W4308506789 cites W2772814084 @default.
- W4308506789 cites W2910830928 @default.
- W4308506789 cites W2950691318 @default.
- W4308506789 cites W2961752875 @default.
- W4308506789 cites W2968626085 @default.
- W4308506789 cites W3010409416 @default.
- W4308506789 cites W3095801175 @default.
- W4308506789 cites W3111295739 @default.
- W4308506789 cites W3121631352 @default.
- W4308506789 cites W3134254717 @default.
- W4308506789 cites W3180645937 @default.
- W4308506789 cites W3206751861 @default.
- W4308506789 cites W4211135774 @default.
- W4308506789 doi "https://doi.org/10.3390/pharmaceutics14112408" @default.
- W4308506789 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36365226" @default.
- W4308506789 hasPublicationYear "2022" @default.
- W4308506789 type Work @default.
- W4308506789 citedByCount "1" @default.
- W4308506789 countsByYear W43085067892022 @default.
- W4308506789 crossrefType "journal-article" @default.
- W4308506789 hasAuthorship W4308506789A5015408416 @default.
- W4308506789 hasAuthorship W4308506789A5019199655 @default.
- W4308506789 hasAuthorship W4308506789A5032813462 @default.
- W4308506789 hasAuthorship W4308506789A5041545765 @default.
- W4308506789 hasAuthorship W4308506789A5056935928 @default.
- W4308506789 hasAuthorship W4308506789A5081499203 @default.
- W4308506789 hasBestOaLocation W43085067891 @default.
- W4308506789 hasConcept C105702510 @default.
- W4308506789 hasConcept C113246987 @default.
- W4308506789 hasConcept C121332964 @default.
- W4308506789 hasConcept C12554922 @default.
- W4308506789 hasConcept C136940099 @default.
- W4308506789 hasConcept C160539049 @default.
- W4308506789 hasConcept C170493617 @default.
- W4308506789 hasConcept C171056886 @default.
- W4308506789 hasConcept C185592680 @default.
- W4308506789 hasConcept C185856081 @default.
- W4308506789 hasConcept C202751555 @default.
- W4308506789 hasConcept C2776880756 @default.
- W4308506789 hasConcept C2777004073 @default.
- W4308506789 hasConcept C2777019933 @default.
- W4308506789 hasConcept C3018498973 @default.
- W4308506789 hasConcept C55493867 @default.
- W4308506789 hasConcept C55637122 @default.
- W4308506789 hasConcept C62520636 @default.
- W4308506789 hasConcept C71924100 @default.
- W4308506789 hasConcept C86803240 @default.
- W4308506789 hasConcept C91881484 @default.
- W4308506789 hasConcept C95444343 @default.
- W4308506789 hasConceptScore W4308506789C105702510 @default.
- W4308506789 hasConceptScore W4308506789C113246987 @default.
- W4308506789 hasConceptScore W4308506789C121332964 @default.
- W4308506789 hasConceptScore W4308506789C12554922 @default.
- W4308506789 hasConceptScore W4308506789C136940099 @default.
- W4308506789 hasConceptScore W4308506789C160539049 @default.
- W4308506789 hasConceptScore W4308506789C170493617 @default.
- W4308506789 hasConceptScore W4308506789C171056886 @default.
- W4308506789 hasConceptScore W4308506789C185592680 @default.
- W4308506789 hasConceptScore W4308506789C185856081 @default.
- W4308506789 hasConceptScore W4308506789C202751555 @default.
- W4308506789 hasConceptScore W4308506789C2776880756 @default.
- W4308506789 hasConceptScore W4308506789C2777004073 @default.
- W4308506789 hasConceptScore W4308506789C2777019933 @default.