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- W4308512607 endingPage "107854" @default.
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- W4308512607 abstract "Intervertebral disc degeneration (IVDD) presents in a variety of ways and is first manifested by loss of nucleus pulposus (NP) cells, so replenishing NP cells is the key to IVDD treatment. The intensive research into the application of polymer materials and the booming development of decellularization technology offers new hope for patients in relieving pain, replacing damaged nucleus pulposus tissue, reversing degenerative disc cascades, maintaining mechanical properties of the spine and even improving conditions. In this review paper, we first briefly describe the anatomy of intervertebral disc (IVD) and the limitations of traditional therapeutic approaches for IVDD, and then focus on a review of research advances in materials for IVD repair and regeneration including polymeric hydrogels and decellularized nucleus pulposus extracellular matrix (dNP-ECM) technology. Hydrogel material is an ideal polymer material for NP repair, with good mechanical properties. At the same time, dNP-ECM scaffold, as a repair material with low immunogenicity, has attracted increasing attention in the field of IVD regeneration. Although these technologies are not yet widely available for clinical use, these treatment strategies may be a promising alternative approach to IVDD treatment and have great research value." @default.
- W4308512607 created "2022-11-12" @default.
- W4308512607 creator A5001488523 @default.
- W4308512607 creator A5004047777 @default.
- W4308512607 creator A5008634943 @default.
- W4308512607 creator A5041864967 @default.
- W4308512607 creator A5063210126 @default.
- W4308512607 creator A5068198157 @default.
- W4308512607 date "2023-01-01" @default.
- W4308512607 modified "2023-09-29" @default.
- W4308512607 title "Polymeric hydrogels and decellularized nucleus pulposus extracellular matrix technology for nucleus pulposus repair and regeneration" @default.
- W4308512607 cites W1269576713 @default.
- W4308512607 cites W1498670501 @default.
- W4308512607 cites W1572077702 @default.
- W4308512607 cites W1892006814 @default.
- W4308512607 cites W1948268354 @default.
- W4308512607 cites W1965352825 @default.
- W4308512607 cites W1970576706 @default.
- W4308512607 cites W1971635936 @default.
- W4308512607 cites W1974715913 @default.
- W4308512607 cites W1982755618 @default.
- W4308512607 cites W1987872284 @default.
- W4308512607 cites W1989752993 @default.
- W4308512607 cites W1993124321 @default.
- W4308512607 cites W1995373597 @default.
- W4308512607 cites W1996144874 @default.
- W4308512607 cites W2003720887 @default.
- W4308512607 cites W2006864740 @default.
- W4308512607 cites W2007851313 @default.
- W4308512607 cites W2010130647 @default.
- W4308512607 cites W2010620009 @default.
- W4308512607 cites W2019958066 @default.
- W4308512607 cites W2021692998 @default.
- W4308512607 cites W2031336983 @default.
- W4308512607 cites W2041997771 @default.
- W4308512607 cites W2043143369 @default.
- W4308512607 cites W2046680726 @default.
- W4308512607 cites W2050475565 @default.
- W4308512607 cites W2050569759 @default.
- W4308512607 cites W2051131440 @default.
- W4308512607 cites W2053358451 @default.
- W4308512607 cites W2059486645 @default.
- W4308512607 cites W2062217024 @default.
- W4308512607 cites W2064091315 @default.
- W4308512607 cites W2066165358 @default.
- W4308512607 cites W2066592854 @default.
- W4308512607 cites W2071762258 @default.
- W4308512607 cites W2075593123 @default.
- W4308512607 cites W2076667099 @default.
- W4308512607 cites W2077940158 @default.
- W4308512607 cites W2096639686 @default.
- W4308512607 cites W2106459436 @default.
- W4308512607 cites W2107519745 @default.
- W4308512607 cites W2107675430 @default.
- W4308512607 cites W2108344016 @default.
- W4308512607 cites W2111763891 @default.
- W4308512607 cites W2118929332 @default.
- W4308512607 cites W2121695733 @default.
- W4308512607 cites W2127956592 @default.
- W4308512607 cites W2152983876 @default.
- W4308512607 cites W2155909615 @default.
- W4308512607 cites W2156461747 @default.
- W4308512607 cites W2159727698 @default.
- W4308512607 cites W2160193515 @default.
- W4308512607 cites W2161134772 @default.
- W4308512607 cites W2163998809 @default.
- W4308512607 cites W2239124976 @default.
- W4308512607 cites W2340154058 @default.
- W4308512607 cites W2345395329 @default.
- W4308512607 cites W2537029179 @default.
- W4308512607 cites W2557975987 @default.
- W4308512607 cites W2572808662 @default.
- W4308512607 cites W2596972615 @default.
- W4308512607 cites W2609961151 @default.
- W4308512607 cites W2610784388 @default.
- W4308512607 cites W2765236784 @default.
- W4308512607 cites W2771705633 @default.
- W4308512607 cites W2788945808 @default.
- W4308512607 cites W2790989829 @default.
- W4308512607 cites W2793819620 @default.
- W4308512607 cites W2800268986 @default.
- W4308512607 cites W2801198579 @default.
- W4308512607 cites W2802553227 @default.
- W4308512607 cites W2888292332 @default.
- W4308512607 cites W2893354205 @default.
- W4308512607 cites W2898284644 @default.
- W4308512607 cites W2898529442 @default.
- W4308512607 cites W2898872070 @default.
- W4308512607 cites W2898875266 @default.
- W4308512607 cites W2900665806 @default.
- W4308512607 cites W2902722609 @default.
- W4308512607 cites W2903389473 @default.
- W4308512607 cites W2909859294 @default.
- W4308512607 cites W2914304916 @default.
- W4308512607 cites W2933222341 @default.
- W4308512607 cites W2942953951 @default.
- W4308512607 cites W2969611214 @default.
- W4308512607 cites W2989006322 @default.