Matches in SemOpenAlex for { <https://semopenalex.org/work/W4308531840> ?p ?o ?g. }
- W4308531840 endingPage "51618" @default.
- W4308531840 startingPage "51602" @default.
- W4308531840 abstract "Recapitulating inherent heterogeneity and complex microarchitectures within confined print volumes for developing implantable constructs that could maintain their structure in vivo has remained challenging. Here, we present a combinational multimaterial and embedded bioprinting approach to fabricate complex tissue constructs that can be implanted postprinting and retain their three-dimensional (3D) shape in vivo. The microfluidics-based single nozzle printhead with computer-controlled pneumatic pressure valves enables laminar flow-based voxelation of up to seven individual bioinks with rapid switching between various bioinks that can solve alignment issues generated during switching multiple nozzles. To improve the spatial organization of various bioinks, printing fidelity with the z-direction, and printing speed, self-healing and biodegradable colloidal gels as support baths are introduced to build complex geometries. Furthermore, the colloidal gels provide suitable microenvironments like native extracellular matrices (ECMs) for achieving cell growths and fast host cell invasion via interconnected microporous networks in vitro and in vivo. Multicompartment microfibers (i.e., solid, core-shell, or donut shape), composed of two different bioink fractions with various lengths or their intravolume space filled by two, four, and six bioink fractions, are successfully printed in the ECM-like support bath. We also print various acellular complex geometries such as pyramids, spirals, and perfusable branched/linear vessels. Successful fabrication of vascularized liver and skeletal muscle tissue constructs show albumin secretion and bundled muscle mimic fibers, respectively. The interconnected microporous networks of colloidal gels result in maintaining printed complex geometries while enabling rapid cell infiltration, in vivo." @default.
- W4308531840 created "2022-11-12" @default.
- W4308531840 creator A5008210979 @default.
- W4308531840 creator A5010576473 @default.
- W4308531840 creator A5019229100 @default.
- W4308531840 creator A5024043802 @default.
- W4308531840 creator A5026575316 @default.
- W4308531840 creator A5028653431 @default.
- W4308531840 creator A5032467563 @default.
- W4308531840 creator A5032820782 @default.
- W4308531840 creator A5036095390 @default.
- W4308531840 creator A5036728585 @default.
- W4308531840 creator A5037025224 @default.
- W4308531840 creator A5041397911 @default.
- W4308531840 creator A5047704678 @default.
- W4308531840 creator A5048939140 @default.
- W4308531840 creator A5061837033 @default.
- W4308531840 creator A5068190398 @default.
- W4308531840 creator A5079961018 @default.
- W4308531840 creator A5087298786 @default.
- W4308531840 creator A5090812801 @default.
- W4308531840 date "2022-11-08" @default.
- W4308531840 modified "2023-10-06" @default.
- W4308531840 title "Tunable and Compartmentalized Multimaterial Bioprinting for Complex Living Tissue Constructs" @default.
- W4308531840 cites W1120477740 @default.
- W4308531840 cites W1615617154 @default.
- W4308531840 cites W1924088822 @default.
- W4308531840 cites W1981699748 @default.
- W4308531840 cites W1983736769 @default.
- W4308531840 cites W1990114409 @default.
- W4308531840 cites W2000534640 @default.
- W4308531840 cites W2052954140 @default.
- W4308531840 cites W2132670761 @default.
- W4308531840 cites W2190264120 @default.
- W4308531840 cites W2232645088 @default.
- W4308531840 cites W2295454854 @default.
- W4308531840 cites W2299693612 @default.
- W4308531840 cites W2416689747 @default.
- W4308531840 cites W2502401296 @default.
- W4308531840 cites W2511720699 @default.
- W4308531840 cites W2551990071 @default.
- W4308531840 cites W2594482393 @default.
- W4308531840 cites W2770298048 @default.
- W4308531840 cites W2801546204 @default.
- W4308531840 cites W2804526029 @default.
- W4308531840 cites W2807117701 @default.
- W4308531840 cites W2886382957 @default.
- W4308531840 cites W2931921805 @default.
- W4308531840 cites W2937732269 @default.
- W4308531840 cites W2937820813 @default.
- W4308531840 cites W2939436287 @default.
- W4308531840 cites W2946663348 @default.
- W4308531840 cites W2954029681 @default.
- W4308531840 cites W2965443828 @default.
- W4308531840 cites W2971539042 @default.
- W4308531840 cites W2984784701 @default.
- W4308531840 cites W2995601983 @default.
- W4308531840 cites W2999836809 @default.
- W4308531840 cites W3000783277 @default.
- W4308531840 cites W3006231048 @default.
- W4308531840 cites W3006893608 @default.
- W4308531840 cites W3012630041 @default.
- W4308531840 cites W3022742761 @default.
- W4308531840 cites W3038624695 @default.
- W4308531840 cites W3083732197 @default.
- W4308531840 cites W3093415549 @default.
- W4308531840 cites W3120884837 @default.
- W4308531840 cites W3123250597 @default.
- W4308531840 cites W3127298807 @default.
- W4308531840 cites W3159866022 @default.
- W4308531840 cites W3185769542 @default.
- W4308531840 cites W3203134233 @default.
- W4308531840 cites W3205014341 @default.
- W4308531840 cites W68186789 @default.
- W4308531840 doi "https://doi.org/10.1021/acsami.2c12585" @default.
- W4308531840 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36346873" @default.
- W4308531840 hasPublicationYear "2022" @default.
- W4308531840 type Work @default.
- W4308531840 citedByCount "3" @default.
- W4308531840 countsByYear W43085318402023 @default.
- W4308531840 crossrefType "journal-article" @default.
- W4308531840 hasAuthorship W4308531840A5008210979 @default.
- W4308531840 hasAuthorship W4308531840A5010576473 @default.
- W4308531840 hasAuthorship W4308531840A5019229100 @default.
- W4308531840 hasAuthorship W4308531840A5024043802 @default.
- W4308531840 hasAuthorship W4308531840A5026575316 @default.
- W4308531840 hasAuthorship W4308531840A5028653431 @default.
- W4308531840 hasAuthorship W4308531840A5032467563 @default.
- W4308531840 hasAuthorship W4308531840A5032820782 @default.
- W4308531840 hasAuthorship W4308531840A5036095390 @default.
- W4308531840 hasAuthorship W4308531840A5036728585 @default.
- W4308531840 hasAuthorship W4308531840A5037025224 @default.
- W4308531840 hasAuthorship W4308531840A5041397911 @default.
- W4308531840 hasAuthorship W4308531840A5047704678 @default.
- W4308531840 hasAuthorship W4308531840A5048939140 @default.
- W4308531840 hasAuthorship W4308531840A5061837033 @default.
- W4308531840 hasAuthorship W4308531840A5068190398 @default.
- W4308531840 hasAuthorship W4308531840A5079961018 @default.