FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4308532056> ?p ?o ?g. }

• W4308532056 endingPage "1034" @default.
• W4308532056 startingPage "1023" @default.
• W4308532056 abstract "The risk of infectious complications after trauma is determined by the amount of injury-related tissue damage and the resulting inflammatory response. Recently, it became possible to measure the neutrophil phenotype in a point-of-care setting. The primary goal of this study was to investigate if immunophenotype categories based on visual recognition of neutrophil subsets are applicable to interpret the inflammatory response to trauma. The secondary goal was to correlate these immunophenotype categories with patient characteristics, injury severity and risk of complications.A cohort study was conducted with patients presented at a level 1 trauma center with injuries of any severity, who routinely underwent neutrophil phenotyping. Data generated by automated point-of-care flow cytometry were prospectively gathered. Neutrophil phenotypes categories were defined by visual assessment of two-dimensional CD16/CD62L dot plots. All patients were categorized in one of the immunophenotype categories. Thereafter, the categories were validated by multidimensional analysis of neutrophil populations, using FlowSOM. All clinical parameters and endpoints were extracted from the trauma registry.The study population consisted of 380 patients. Seven distinct immunophenotype Categories (0-6) were defined, that consisted of different neutrophil populations as validated by FlowSOM. Injury severity scores and risk of infectious complications increased with ascending immunophenotype Categories 3-6. Injury severity was similarly low in Categories 0-2.The distribution of neutrophil subsets that were described in phenotype categories is easily recognizable for clinicians at the bedside. Even more, multidimensional analysis demonstrated these categories to be distinct subsets of neutrophils. Identification of trauma patients at risk for infectious complications by monitoring the immunophenotype category is a further improvement of personalized and point-of-care decision-making in trauma care." @default.
• W4308532056 created "2022-11-12" @default.
• W4308532056 creator A5004347141 @default.
• W4308532056 creator A5010814791 @default.
• W4308532056 creator A5030783314 @default.
• W4308532056 creator A5031159404 @default.
• W4308532056 creator A5055466650 @default.
• W4308532056 creator A5056868148 @default.
• W4308532056 creator A5063605052 @default.
• W4308532056 creator A5069040006 @default.
• W4308532056 date "2022-11-08" @default.
• W4308532056 modified "2023-09-27" @default.
• W4308532056 title "Visualization of the inflammatory response to injury by neutrophil phenotype categories" @default.
• W4308532056 cites W1969354148 @default.
• W4308532056 cites W1973174792 @default.
• W4308532056 cites W1981904722 @default.
• W4308532056 cites W1996094005 @default.
• W4308532056 cites W2019823288 @default.
• W4308532056 cites W2025733849 @default.
• W4308532056 cites W2032227357 @default.
• W4308532056 cites W2046185880 @default.
• W4308532056 cites W2053468540 @default.
• W4308532056 cites W2063530517 @default.
• W4308532056 cites W2162251862 @default.
• W4308532056 cites W2164007663 @default.
• W4308532056 cites W2164637425 @default.
• W4308532056 cites W2170003167 @default.
• W4308532056 cites W2221016424 @default.
• W4308532056 cites W2728815668 @default.
• W4308532056 cites W2808512787 @default.
• W4308532056 cites W2884005666 @default.
• W4308532056 cites W2947594787 @default.
• W4308532056 cites W2968290635 @default.
• W4308532056 cites W3005471483 @default.
• W4308532056 cites W3010839402 @default.
• W4308532056 cites W3037348462 @default.
• W4308532056 cites W3043764837 @default.
• W4308532056 cites W3087583581 @default.
• W4308532056 cites W3114525075 @default.
• W4308532056 cites W3177060291 @default.
• W4308532056 cites W3178387633 @default.
• W4308532056 cites W4205397563 @default.
• W4308532056 cites W4297905728 @default.
• W4308532056 doi "https://doi.org/10.1007/s00068-022-02134-3" @default.
• W4308532056 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36348032" @default.
• W4308532056 hasPublicationYear "2022" @default.
• W4308532056 type Work @default.
• W4308532056 citedByCount "1" @default.
• W4308532056 countsByYear W43085320562022 @default.
• W4308532056 crossrefType "journal-article" @default.
• W4308532056 hasAuthorship W4308532056A5004347141 @default.
• W4308532056 hasAuthorship W4308532056A5010814791 @default.
• W4308532056 hasAuthorship W4308532056A5030783314 @default.
• W4308532056 hasAuthorship W4308532056A5031159404 @default.
• W4308532056 hasAuthorship W4308532056A5055466650 @default.
• W4308532056 hasAuthorship W4308532056A5056868148 @default.
• W4308532056 hasAuthorship W4308532056A5063605052 @default.
• W4308532056 hasAuthorship W4308532056A5069040006 @default.
• W4308532056 hasBestOaLocation W43085320561 @default.
• W4308532056 hasConcept C114684123 @default.
• W4308532056 hasConcept C126322002 @default.
• W4308532056 hasConcept C142724271 @default.
• W4308532056 hasConcept C147483822 @default.
• W4308532056 hasConcept C167672396 @default.
• W4308532056 hasConcept C190385971 @default.
• W4308532056 hasConcept C196166836 @default.
• W4308532056 hasConcept C203014093 @default.
• W4308532056 hasConcept C2777063308 @default.
• W4308532056 hasConcept C2781462264 @default.
• W4308532056 hasConcept C2908647359 @default.
• W4308532056 hasConcept C29730261 @default.
• W4308532056 hasConcept C3017944768 @default.
• W4308532056 hasConcept C545542383 @default.
• W4308532056 hasConcept C553184892 @default.
• W4308532056 hasConcept C71924100 @default.
• W4308532056 hasConcept C72563966 @default.
• W4308532056 hasConcept C74133956 @default.
• W4308532056 hasConcept C85004164 @default.
• W4308532056 hasConcept C99454951 @default.
• W4308532056 hasConceptScore W4308532056C114684123 @default.
• W4308532056 hasConceptScore W4308532056C126322002 @default.
• W4308532056 hasConceptScore W4308532056C142724271 @default.
• W4308532056 hasConceptScore W4308532056C147483822 @default.
• W4308532056 hasConceptScore W4308532056C167672396 @default.
• W4308532056 hasConceptScore W4308532056C190385971 @default.
• W4308532056 hasConceptScore W4308532056C196166836 @default.
• W4308532056 hasConceptScore W4308532056C203014093 @default.
• W4308532056 hasConceptScore W4308532056C2777063308 @default.
• W4308532056 hasConceptScore W4308532056C2781462264 @default.
• W4308532056 hasConceptScore W4308532056C2908647359 @default.
• W4308532056 hasConceptScore W4308532056C29730261 @default.
• W4308532056 hasConceptScore W4308532056C3017944768 @default.
• W4308532056 hasConceptScore W4308532056C545542383 @default.
• W4308532056 hasConceptScore W4308532056C553184892 @default.
• W4308532056 hasConceptScore W4308532056C71924100 @default.
• W4308532056 hasConceptScore W4308532056C72563966 @default.
• W4308532056 hasConceptScore W4308532056C74133956 @default.
• W4308532056 hasConceptScore W4308532056C85004164 @default.

• next