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- W4308581279 endingPage "13678" @default.
- W4308581279 startingPage "13678" @default.
- W4308581279 abstract "The underlying causes of Parkinson's disease are complex, and besides recent advances in elucidating relevant disease mechanisms, no disease-modifying treatments are currently available. One proposed pathophysiological hallmark is mitochondrial dysfunction, and a plethora of evidence points toward the interconnected nature of mitochondria in neuronal homeostasis. This also extends to iron and neuromelanin metabolism, two biochemical processes highly relevant to individual disease manifestation and progression. Modern neuroimaging methods help to gain in vivo insights into these intertwined pathways and may pave the road to individualized medicine in this debilitating disorder. In this narrative review, we will highlight the biological rationale for studying these pathways, how distinct neuroimaging methods can be applied in patients, their respective limitations, and which challenges need to be overcome for successful implementation in clinical studies." @default.
- W4308581279 created "2022-11-12" @default.
- W4308581279 creator A5021779445 @default.
- W4308581279 creator A5057412600 @default.
- W4308581279 creator A5076156979 @default.
- W4308581279 creator A5087337463 @default.
- W4308581279 date "2022-11-08" @default.
- W4308581279 modified "2023-10-17" @default.
- W4308581279 title "Iron- and Neuromelanin-Weighted Neuroimaging to Study Mitochondrial Dysfunction in Patients with Parkinson’s Disease" @default.
- W4308581279 cites W1672024307 @default.
- W4308581279 cites W1715607066 @default.
- W4308581279 cites W1822968832 @default.
- W4308581279 cites W1870257566 @default.
- W4308581279 cites W1905490847 @default.
- W4308581279 cites W1906698008 @default.
- W4308581279 cites W1913653254 @default.
- W4308581279 cites W1937882124 @default.
- W4308581279 cites W1966587486 @default.
- W4308581279 cites W1973385523 @default.
- W4308581279 cites W1979454099 @default.
- W4308581279 cites W1986696867 @default.
- W4308581279 cites W1986740107 @default.
- W4308581279 cites W1990017244 @default.
- W4308581279 cites W1990082255 @default.
- W4308581279 cites W2003816004 @default.
- W4308581279 cites W2004628001 @default.
- W4308581279 cites W2008602421 @default.
- W4308581279 cites W2010686114 @default.
- W4308581279 cites W2011834328 @default.
- W4308581279 cites W2012508583 @default.
- W4308581279 cites W2013503732 @default.
- W4308581279 cites W2022840256 @default.
- W4308581279 cites W2027125459 @default.
- W4308581279 cites W2032587951 @default.
- W4308581279 cites W2032870207 @default.
- W4308581279 cites W2036612609 @default.
- W4308581279 cites W2049233581 @default.
- W4308581279 cites W2054421268 @default.
- W4308581279 cites W2061388101 @default.
- W4308581279 cites W2069650508 @default.
- W4308581279 cites W2081533023 @default.
- W4308581279 cites W2086361121 @default.
- W4308581279 cites W2111601269 @default.
- W4308581279 cites W2112867510 @default.
- W4308581279 cites W2114655563 @default.
- W4308581279 cites W2116487401 @default.
- W4308581279 cites W2124336244 @default.
- W4308581279 cites W2144357875 @default.
- W4308581279 cites W2159134373 @default.
- W4308581279 cites W2194993935 @default.
- W4308581279 cites W2258429837 @default.
- W4308581279 cites W2261476050 @default.
- W4308581279 cites W2265948808 @default.
- W4308581279 cites W2275500828 @default.
- W4308581279 cites W2284752289 @default.
- W4308581279 cites W2299927533 @default.
- W4308581279 cites W2331290626 @default.
- W4308581279 cites W2375352890 @default.
- W4308581279 cites W2408015440 @default.
- W4308581279 cites W2412292374 @default.
- W4308581279 cites W2516289434 @default.
- W4308581279 cites W2523393682 @default.
- W4308581279 cites W2529635825 @default.
- W4308581279 cites W2555006703 @default.
- W4308581279 cites W2564110825 @default.
- W4308581279 cites W2583166443 @default.
- W4308581279 cites W2591776556 @default.
- W4308581279 cites W2599538630 @default.
- W4308581279 cites W2600025798 @default.
- W4308581279 cites W2600483363 @default.
- W4308581279 cites W2603592523 @default.
- W4308581279 cites W2604383919 @default.
- W4308581279 cites W2606065277 @default.
- W4308581279 cites W2609085690 @default.
- W4308581279 cites W2615734863 @default.
- W4308581279 cites W2738204471 @default.
- W4308581279 cites W2752710053 @default.
- W4308581279 cites W2760325968 @default.
- W4308581279 cites W2763360727 @default.
- W4308581279 cites W2782376926 @default.
- W4308581279 cites W2797850641 @default.
- W4308581279 cites W2803039601 @default.
- W4308581279 cites W2804998168 @default.
- W4308581279 cites W2809129539 @default.
- W4308581279 cites W2883188722 @default.
- W4308581279 cites W2898132477 @default.
- W4308581279 cites W2904404980 @default.
- W4308581279 cites W2905515525 @default.
- W4308581279 cites W2913169616 @default.
- W4308581279 cites W2914531241 @default.
- W4308581279 cites W2915476106 @default.
- W4308581279 cites W2919982464 @default.
- W4308581279 cites W2921107593 @default.
- W4308581279 cites W2947966619 @default.
- W4308581279 cites W2950221893 @default.
- W4308581279 cites W2950453599 @default.
- W4308581279 cites W2956068311 @default.
- W4308581279 cites W2956863190 @default.