Matches in SemOpenAlex for { <https://semopenalex.org/work/W4308584583> ?p ?o ?g. }
Showing items 1 to 69 of
69
with 100 items per page.
- W4308584583 abstract "Introduction: Preeclampsia (PE) is a hypertensive disorder of pregnancy (HDP). DLX5 plays an important role in the migration and differentiation of subglobus pallidus precursor cells. Material and methods: We established a zebrafish line expressing high levels of DLX5 and investigated changes in behavior and development of the nervous system. Results: The ratios of brain volume area to whole body area at 96 hpf zebrafish in the experimental group (gRNA+CasRx) were significantly lower than the WT group and the negative control group (casRx)(P<0.01). Behavioral trajectory distances and movement speeds exhibited by the 6th day of development in zebrafish in the experimental group (gRNA+CasRx) were significantly shorter (P<0.01) and lower (P<0.05) than the negative control group (gRNA+CasRx), respectively. Conclusions : Data suggested that the increased expression levels of DLX5 can inhibit brain volume development and behavioral activities in zebrafish. Maybe the high expression levels of DLX5 in the pathological state of PE can inhibit the development of the nervous system in offspring." @default.
- W4308584583 created "2022-11-12" @default.
- W4308584583 creator A5022557436 @default.
- W4308584583 creator A5042129832 @default.
- W4308584583 creator A5044165747 @default.
- W4308584583 creator A5074631989 @default.
- W4308584583 creator A5089595619 @default.
- W4308584583 date "2022-11-08" @default.
- W4308584583 modified "2023-10-16" @default.
- W4308584583 title "Increased expression levels of DLX5 inhibit the development of the nervous system" @default.
- W4308584583 doi "https://doi.org/10.22541/au.166791068.83855214/v1" @default.
- W4308584583 hasPublicationYear "2022" @default.
- W4308584583 type Work @default.
- W4308584583 citedByCount "0" @default.
- W4308584583 crossrefType "posted-content" @default.
- W4308584583 hasAuthorship W4308584583A5022557436 @default.
- W4308584583 hasAuthorship W4308584583A5042129832 @default.
- W4308584583 hasAuthorship W4308584583A5044165747 @default.
- W4308584583 hasAuthorship W4308584583A5074631989 @default.
- W4308584583 hasAuthorship W4308584583A5089595619 @default.
- W4308584583 hasBestOaLocation W43085845831 @default.
- W4308584583 hasConcept C104317684 @default.
- W4308584583 hasConcept C112672928 @default.
- W4308584583 hasConcept C117072055 @default.
- W4308584583 hasConcept C121587040 @default.
- W4308584583 hasConcept C126322002 @default.
- W4308584583 hasConcept C134018914 @default.
- W4308584583 hasConcept C150194340 @default.
- W4308584583 hasConcept C169760540 @default.
- W4308584583 hasConcept C2776878037 @default.
- W4308584583 hasConcept C2779234561 @default.
- W4308584583 hasConcept C529278444 @default.
- W4308584583 hasConcept C54355233 @default.
- W4308584583 hasConcept C55493867 @default.
- W4308584583 hasConcept C71924100 @default.
- W4308584583 hasConcept C86803240 @default.
- W4308584583 hasConceptScore W4308584583C104317684 @default.
- W4308584583 hasConceptScore W4308584583C112672928 @default.
- W4308584583 hasConceptScore W4308584583C117072055 @default.
- W4308584583 hasConceptScore W4308584583C121587040 @default.
- W4308584583 hasConceptScore W4308584583C126322002 @default.
- W4308584583 hasConceptScore W4308584583C134018914 @default.
- W4308584583 hasConceptScore W4308584583C150194340 @default.
- W4308584583 hasConceptScore W4308584583C169760540 @default.
- W4308584583 hasConceptScore W4308584583C2776878037 @default.
- W4308584583 hasConceptScore W4308584583C2779234561 @default.
- W4308584583 hasConceptScore W4308584583C529278444 @default.
- W4308584583 hasConceptScore W4308584583C54355233 @default.
- W4308584583 hasConceptScore W4308584583C55493867 @default.
- W4308584583 hasConceptScore W4308584583C71924100 @default.
- W4308584583 hasConceptScore W4308584583C86803240 @default.
- W4308584583 hasLocation W43085845831 @default.
- W4308584583 hasLocation W43085845832 @default.
- W4308584583 hasLocation W43085845833 @default.
- W4308584583 hasOpenAccess W4308584583 @default.
- W4308584583 hasPrimaryLocation W43085845831 @default.
- W4308584583 hasRelatedWork W1591616590 @default.
- W4308584583 hasRelatedWork W1988626231 @default.
- W4308584583 hasRelatedWork W2004424018 @default.
- W4308584583 hasRelatedWork W2009428258 @default.
- W4308584583 hasRelatedWork W2064652474 @default.
- W4308584583 hasRelatedWork W2110681150 @default.
- W4308584583 hasRelatedWork W2127828366 @default.
- W4308584583 hasRelatedWork W2500314183 @default.
- W4308584583 hasRelatedWork W2520636841 @default.
- W4308584583 hasRelatedWork W3160140598 @default.
- W4308584583 isParatext "false" @default.
- W4308584583 isRetracted "false" @default.
- W4308584583 workType "article" @default.