Matches in SemOpenAlex for { <https://semopenalex.org/work/W4308587683> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W4308587683 endingPage "2098" @default.
- W4308587683 startingPage "2093" @default.
- W4308587683 abstract "Purpose: To investigate the possible effects of scoparone on the viability, apoptosis and motility of liver cancer cells, as well as the mechanism of action. 
 Methods: CCK-8 and colony formation assays were carried out to determine liver cancer cell viability, while flow cytometry (FCM) and Immunoblot assays were performed to evaluate cell apoptosis. Wound closure and Transwell assays were performed to determine the effect of scoparone on cell motility, while immunoblot assays were performed to assess the effect of the compound on MAPK pathway of liver cancer cells. 
 Results: Scoparone suppressed the viability of Hep3B2 and Huh-7 cells (p < 0.01), as well as the apoptosis and motility of the cells (p < 0.01). Furthermore, scoparone inhibited the growth of liver cancer cells via MAPK pathway. 
 Conclusion: Scoparone suppresses liver cancer cell growth via MAPK pathway, and is thus a promising drug for liver cancer treatment. However, in vivo studies are required to validate these findings." @default.
- W4308587683 created "2022-11-12" @default.
- W4308587683 creator A5019963412 @default.
- W4308587683 creator A5032612009 @default.
- W4308587683 date "2022-11-03" @default.
- W4308587683 modified "2023-09-30" @default.
- W4308587683 title "Scoparone inhibits the growth of liver cancer cells by regulating MAPK signaling pathway" @default.
- W4308587683 doi "https://doi.org/10.4314/tjpr.v21i10.8" @default.
- W4308587683 hasPublicationYear "2022" @default.
- W4308587683 type Work @default.
- W4308587683 citedByCount "0" @default.
- W4308587683 crossrefType "journal-article" @default.
- W4308587683 hasAuthorship W4308587683A5019963412 @default.
- W4308587683 hasAuthorship W4308587683A5032612009 @default.
- W4308587683 hasBestOaLocation W43085876831 @default.
- W4308587683 hasConcept C121608353 @default.
- W4308587683 hasConcept C1491633281 @default.
- W4308587683 hasConcept C153911025 @default.
- W4308587683 hasConcept C185592680 @default.
- W4308587683 hasConcept C190283241 @default.
- W4308587683 hasConcept C2776231280 @default.
- W4308587683 hasConcept C2778019345 @default.
- W4308587683 hasConcept C502942594 @default.
- W4308587683 hasConcept C53227056 @default.
- W4308587683 hasConcept C54355233 @default.
- W4308587683 hasConcept C553184892 @default.
- W4308587683 hasConcept C55493867 @default.
- W4308587683 hasConcept C57074206 @default.
- W4308587683 hasConcept C58207958 @default.
- W4308587683 hasConcept C62112901 @default.
- W4308587683 hasConcept C62478195 @default.
- W4308587683 hasConcept C86803240 @default.
- W4308587683 hasConcept C95444343 @default.
- W4308587683 hasConcept C96232424 @default.
- W4308587683 hasConceptScore W4308587683C121608353 @default.
- W4308587683 hasConceptScore W4308587683C1491633281 @default.
- W4308587683 hasConceptScore W4308587683C153911025 @default.
- W4308587683 hasConceptScore W4308587683C185592680 @default.
- W4308587683 hasConceptScore W4308587683C190283241 @default.
- W4308587683 hasConceptScore W4308587683C2776231280 @default.
- W4308587683 hasConceptScore W4308587683C2778019345 @default.
- W4308587683 hasConceptScore W4308587683C502942594 @default.
- W4308587683 hasConceptScore W4308587683C53227056 @default.
- W4308587683 hasConceptScore W4308587683C54355233 @default.
- W4308587683 hasConceptScore W4308587683C553184892 @default.
- W4308587683 hasConceptScore W4308587683C55493867 @default.
- W4308587683 hasConceptScore W4308587683C57074206 @default.
- W4308587683 hasConceptScore W4308587683C58207958 @default.
- W4308587683 hasConceptScore W4308587683C62112901 @default.
- W4308587683 hasConceptScore W4308587683C62478195 @default.
- W4308587683 hasConceptScore W4308587683C86803240 @default.
- W4308587683 hasConceptScore W4308587683C95444343 @default.
- W4308587683 hasConceptScore W4308587683C96232424 @default.
- W4308587683 hasIssue "10" @default.
- W4308587683 hasLocation W43085876831 @default.
- W4308587683 hasOpenAccess W4308587683 @default.
- W4308587683 hasPrimaryLocation W43085876831 @default.
- W4308587683 hasRelatedWork W2350294409 @default.
- W4308587683 hasRelatedWork W2354128257 @default.
- W4308587683 hasRelatedWork W2354735832 @default.
- W4308587683 hasRelatedWork W2371611592 @default.
- W4308587683 hasRelatedWork W2382230817 @default.
- W4308587683 hasRelatedWork W2386361724 @default.
- W4308587683 hasRelatedWork W2386605958 @default.
- W4308587683 hasRelatedWork W2386702156 @default.
- W4308587683 hasRelatedWork W2410520497 @default.
- W4308587683 hasRelatedWork W3044344817 @default.
- W4308587683 hasVolume "21" @default.
- W4308587683 isParatext "false" @default.
- W4308587683 isRetracted "false" @default.
- W4308587683 workType "article" @default.