Matches in SemOpenAlex for { <https://semopenalex.org/work/W4308602292> ?p ?o ?g. }
- W4308602292 endingPage "1824" @default.
- W4308602292 startingPage "1824" @default.
- W4308602292 abstract "SARS-CoV-2 infection leads to a heterogenous spectrum of clinical conditions ranging from self-limiting upper airway infection to severe respiratory failure. Carbocysteine is a thioether mucolytic with antioxidant and anti-inflammatory activities. Carbocysteine has been shown to have anti-viral effects on human rhinovirus, RSV and the influenza virus as well as interfering with upper airway ciliary motility, the first site of SARS-CoV-2 infection, leading to more effective mucus clearance and potential containment of viral spread towards the lower airway. Positive effects, in terms of limiting superimposed bacterial infection and reducing oxidative stress, have also been documented in COPD patients. Accordingly, Carbocysteine should also be considered in both post-exposure prophylaxis and early-phase treatment of COVID-19 in combination with other agents (monoclonal antibodies, antivirals, non-steroidal anti-inflammatory agents, and inhaled corticosteroids). In this review, we explored the pharmacokinetic and pharmacodynamic aspects of Carbocysteine to delineate its potential therapeutic impact in patients with COVID-19." @default.
- W4308602292 created "2022-11-13" @default.
- W4308602292 creator A5003946214 @default.
- W4308602292 creator A5026376822 @default.
- W4308602292 creator A5028834608 @default.
- W4308602292 creator A5030701726 @default.
- W4308602292 creator A5049545477 @default.
- W4308602292 creator A5054281025 @default.
- W4308602292 creator A5060089859 @default.
- W4308602292 creator A5062907116 @default.
- W4308602292 creator A5073420952 @default.
- W4308602292 date "2022-11-08" @default.
- W4308602292 modified "2023-09-26" @default.
- W4308602292 title "Mucolytic and Antioxidant Properties of Carbocysteine as a Strategy in COVID-19 Therapy" @default.
- W4308602292 cites W1537234007 @default.
- W4308602292 cites W1763742850 @default.
- W4308602292 cites W1889566728 @default.
- W4308602292 cites W1974764865 @default.
- W4308602292 cites W1979866283 @default.
- W4308602292 cites W1992675032 @default.
- W4308602292 cites W1998981970 @default.
- W4308602292 cites W2000843748 @default.
- W4308602292 cites W2014935443 @default.
- W4308602292 cites W2022905205 @default.
- W4308602292 cites W2025855341 @default.
- W4308602292 cites W2029434526 @default.
- W4308602292 cites W2035936908 @default.
- W4308602292 cites W2039167760 @default.
- W4308602292 cites W2043916189 @default.
- W4308602292 cites W2047948148 @default.
- W4308602292 cites W2057395321 @default.
- W4308602292 cites W2057759589 @default.
- W4308602292 cites W2065662162 @default.
- W4308602292 cites W2071527093 @default.
- W4308602292 cites W2075572937 @default.
- W4308602292 cites W2103916161 @default.
- W4308602292 cites W2104316143 @default.
- W4308602292 cites W2105062499 @default.
- W4308602292 cites W2107872142 @default.
- W4308602292 cites W2112393165 @default.
- W4308602292 cites W2122924641 @default.
- W4308602292 cites W2123978785 @default.
- W4308602292 cites W2125359843 @default.
- W4308602292 cites W2127748163 @default.
- W4308602292 cites W2130937986 @default.
- W4308602292 cites W2140464775 @default.
- W4308602292 cites W2143916862 @default.
- W4308602292 cites W2146801981 @default.
- W4308602292 cites W2154203503 @default.
- W4308602292 cites W2159769779 @default.
- W4308602292 cites W2164205372 @default.
- W4308602292 cites W2308905527 @default.
- W4308602292 cites W2347439164 @default.
- W4308602292 cites W2418706128 @default.
- W4308602292 cites W2430858641 @default.
- W4308602292 cites W2468021853 @default.
- W4308602292 cites W2522689183 @default.
- W4308602292 cites W2564218464 @default.
- W4308602292 cites W2765948467 @default.
- W4308602292 cites W2771115831 @default.
- W4308602292 cites W2803032401 @default.
- W4308602292 cites W2895182361 @default.
- W4308602292 cites W2956716141 @default.
- W4308602292 cites W3008090866 @default.
- W4308602292 cites W3013689008 @default.
- W4308602292 cites W3017125154 @default.
- W4308602292 cites W3023334190 @default.
- W4308602292 cites W3025408376 @default.
- W4308602292 cites W3025699671 @default.
- W4308602292 cites W3025781472 @default.
- W4308602292 cites W3033065415 @default.
- W4308602292 cites W3036843350 @default.
- W4308602292 cites W3037965408 @default.
- W4308602292 cites W3040795076 @default.
- W4308602292 cites W3041667892 @default.
- W4308602292 cites W3042693720 @default.
- W4308602292 cites W3043156119 @default.
- W4308602292 cites W3044905147 @default.
- W4308602292 cites W3045927404 @default.
- W4308602292 cites W3047978274 @default.
- W4308602292 cites W3048994085 @default.
- W4308602292 cites W3080162924 @default.
- W4308602292 cites W3092181020 @default.
- W4308602292 cites W3095048012 @default.
- W4308602292 cites W3096543821 @default.
- W4308602292 cites W3104092741 @default.
- W4308602292 cites W3113957998 @default.
- W4308602292 cites W3115015061 @default.
- W4308602292 cites W3164560622 @default.
- W4308602292 cites W3176881890 @default.
- W4308602292 cites W3197448026 @default.
- W4308602292 cites W3208987884 @default.
- W4308602292 cites W41725127 @default.
- W4308602292 cites W4206183808 @default.
- W4308602292 cites W4210642183 @default.
- W4308602292 cites W4212766018 @default.
- W4308602292 cites W4225001781 @default.
- W4308602292 cites W4238816861 @default.