Matches in SemOpenAlex for { <https://semopenalex.org/work/W4308615811> ?p ?o ?g. }
- W4308615811 abstract "Chromosome instability (CIN) is an important driver of cancer initiation, progression, drug resistance, and aging. As such, genes whose inhibition suppresses CIN are potential therapeutic targets. We report here that deletion of an accessory DNA helicase, Rrm3, suppresses high CIN caused by a wide range of genetic or pharmacological perturbations in yeast. Although this helicase mutant has altered cell cycle dynamics, suppression of CIN by rrm3∆ is independent of the DNA damage and spindle assembly checkpoints. Instead, the rrm3∆ mutant may have increased kinetochore-microtubule error correction due to an altered localization of Aurora B kinase and associated phosphatase, PP2A-Rts1." @default.
- W4308615811 created "2022-11-13" @default.
- W4308615811 creator A5031543598 @default.
- W4308615811 creator A5071279315 @default.
- W4308615811 creator A5074399628 @default.
- W4308615811 creator A5078671525 @default.
- W4308615811 date "2023-01-01" @default.
- W4308615811 modified "2023-10-16" @default.
- W4308615811 title "Suppression of chromosome instability by targeting a DNA helicase in budding yeast" @default.
- W4308615811 cites W1545483273 @default.
- W4308615811 cites W1683995796 @default.
- W4308615811 cites W1757201082 @default.
- W4308615811 cites W1832254521 @default.
- W4308615811 cites W1966509265 @default.
- W4308615811 cites W1966669440 @default.
- W4308615811 cites W1967152157 @default.
- W4308615811 cites W1969299223 @default.
- W4308615811 cites W1970471893 @default.
- W4308615811 cites W1971638490 @default.
- W4308615811 cites W1972736799 @default.
- W4308615811 cites W1992906999 @default.
- W4308615811 cites W1995905083 @default.
- W4308615811 cites W2002246796 @default.
- W4308615811 cites W2004099247 @default.
- W4308615811 cites W2011946829 @default.
- W4308615811 cites W2015195697 @default.
- W4308615811 cites W2020099456 @default.
- W4308615811 cites W2029971236 @default.
- W4308615811 cites W2032475954 @default.
- W4308615811 cites W2035542663 @default.
- W4308615811 cites W2036014201 @default.
- W4308615811 cites W2038591876 @default.
- W4308615811 cites W2045808404 @default.
- W4308615811 cites W2045829974 @default.
- W4308615811 cites W2048897962 @default.
- W4308615811 cites W2052740988 @default.
- W4308615811 cites W2053259460 @default.
- W4308615811 cites W2056668426 @default.
- W4308615811 cites W2075447540 @default.
- W4308615811 cites W2076814468 @default.
- W4308615811 cites W2079321797 @default.
- W4308615811 cites W2079924690 @default.
- W4308615811 cites W2080862728 @default.
- W4308615811 cites W2083158919 @default.
- W4308615811 cites W2083942911 @default.
- W4308615811 cites W2083980111 @default.
- W4308615811 cites W2084833108 @default.
- W4308615811 cites W2091204939 @default.
- W4308615811 cites W2098609152 @default.
- W4308615811 cites W2104499996 @default.
- W4308615811 cites W2108147869 @default.
- W4308615811 cites W2109431615 @default.
- W4308615811 cites W2122965413 @default.
- W4308615811 cites W2125280178 @default.
- W4308615811 cites W2129920175 @default.
- W4308615811 cites W2132809415 @default.
- W4308615811 cites W2135783868 @default.
- W4308615811 cites W2136008846 @default.
- W4308615811 cites W2138429565 @default.
- W4308615811 cites W2145719044 @default.
- W4308615811 cites W2149686649 @default.
- W4308615811 cites W2149953930 @default.
- W4308615811 cites W2153472959 @default.
- W4308615811 cites W2159473731 @default.
- W4308615811 cites W2165057124 @default.
- W4308615811 cites W2165860917 @default.
- W4308615811 cites W2169016078 @default.
- W4308615811 cites W2326454182 @default.
- W4308615811 cites W2502135420 @default.
- W4308615811 cites W2545677203 @default.
- W4308615811 cites W2558797341 @default.
- W4308615811 cites W2559983447 @default.
- W4308615811 cites W2611631698 @default.
- W4308615811 cites W2754945126 @default.
- W4308615811 cites W2766401179 @default.
- W4308615811 cites W2901434833 @default.
- W4308615811 cites W2946535916 @default.
- W4308615811 cites W2970545154 @default.
- W4308615811 cites W3006859342 @default.
- W4308615811 cites W3136542714 @default.
- W4308615811 doi "https://doi.org/10.1091/mbc.e22-09-0395" @default.
- W4308615811 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36350688" @default.
- W4308615811 hasPublicationYear "2023" @default.
- W4308615811 type Work @default.
- W4308615811 citedByCount "0" @default.
- W4308615811 crossrefType "journal-article" @default.
- W4308615811 hasAuthorship W4308615811A5031543598 @default.
- W4308615811 hasAuthorship W4308615811A5071279315 @default.
- W4308615811 hasAuthorship W4308615811A5074399628 @default.
- W4308615811 hasAuthorship W4308615811A5078671525 @default.
- W4308615811 hasBestOaLocation W43086158112 @default.
- W4308615811 hasConcept C104317684 @default.
- W4308615811 hasConcept C105696609 @default.
- W4308615811 hasConcept C134935766 @default.
- W4308615811 hasConcept C140752955 @default.
- W4308615811 hasConcept C143065580 @default.
- W4308615811 hasConcept C143425029 @default.
- W4308615811 hasConcept C161223559 @default.
- W4308615811 hasConcept C178169997 @default.
- W4308615811 hasConcept C192838845 @default.