Matches in SemOpenAlex for { <https://semopenalex.org/work/W4308620412> ?p ?o ?g. }
- W4308620412 endingPage "105545" @default.
- W4308620412 startingPage "105545" @default.
- W4308620412 abstract "How organisms cope with coldness and high pressure in the hadal zone remains poorly understood. Here, we sequenced and assembled the genome of hadal sea cucumber Paelopatides sp. Yap with high quality and explored its potential mechanisms for deep-sea adaptation. First, the expansion of ACOX1 for rate-limiting enzyme in the DHA synthesis pathway, increased DHA content in the phospholipid bilayer, and positive selection of EPT1 may maintain cell membrane fluidity. Second, three genes for translation initiation factors and two for ribosomal proteins underwent expansion, and three ribosomal protein genes were positively selected, which may ameliorate the protein synthesis inhibition or ribosome dissociation in the hadal zone. Third, expansion and positive selection of genes associated with stalled replication fork recovery and DNA repair suggest improvements in DNA protection. This is the first genome sequence of a hadal invertebrate. Our results provide insights into the genetic adaptations used by invertebrate in deep oceans." @default.
- W4308620412 created "2022-11-13" @default.
- W4308620412 creator A5000006051 @default.
- W4308620412 creator A5012306799 @default.
- W4308620412 creator A5020282567 @default.
- W4308620412 creator A5020572267 @default.
- W4308620412 creator A5022617539 @default.
- W4308620412 creator A5025283381 @default.
- W4308620412 creator A5038031738 @default.
- W4308620412 creator A5040035637 @default.
- W4308620412 creator A5046192350 @default.
- W4308620412 creator A5074782287 @default.
- W4308620412 creator A5078777969 @default.
- W4308620412 creator A5089582674 @default.
- W4308620412 date "2022-12-01" @default.
- W4308620412 modified "2023-10-14" @default.
- W4308620412 title "The genome of a hadal sea cucumber reveals novel adaptive strategies to deep-sea environments" @default.
- W4308620412 cites W1490178827 @default.
- W4308620412 cites W1493586151 @default.
- W4308620412 cites W1523556480 @default.
- W4308620412 cites W1530179459 @default.
- W4308620412 cites W1540931455 @default.
- W4308620412 cites W1549158836 @default.
- W4308620412 cites W1570361288 @default.
- W4308620412 cites W1590028580 @default.
- W4308620412 cites W171067487 @default.
- W4308620412 cites W175796641 @default.
- W4308620412 cites W1774003058 @default.
- W4308620412 cites W1819983349 @default.
- W4308620412 cites W1852326592 @default.
- W4308620412 cites W1853965828 @default.
- W4308620412 cites W1942110646 @default.
- W4308620412 cites W1970578083 @default.
- W4308620412 cites W1973013931 @default.
- W4308620412 cites W1973638247 @default.
- W4308620412 cites W1974222493 @default.
- W4308620412 cites W1982855075 @default.
- W4308620412 cites W1984215279 @default.
- W4308620412 cites W1992848965 @default.
- W4308620412 cites W1993541870 @default.
- W4308620412 cites W1996944173 @default.
- W4308620412 cites W1999574084 @default.
- W4308620412 cites W2002710548 @default.
- W4308620412 cites W2008410413 @default.
- W4308620412 cites W2011305330 @default.
- W4308620412 cites W2011657487 @default.
- W4308620412 cites W2018314772 @default.
- W4308620412 cites W2022070591 @default.
- W4308620412 cites W2022411566 @default.
- W4308620412 cites W2024027763 @default.
- W4308620412 cites W2024703739 @default.
- W4308620412 cites W2027958460 @default.
- W4308620412 cites W2030054318 @default.
- W4308620412 cites W2039616841 @default.
- W4308620412 cites W2040860750 @default.
- W4308620412 cites W2043384775 @default.
- W4308620412 cites W2052266552 @default.
- W4308620412 cites W2055079033 @default.
- W4308620412 cites W2056815427 @default.
- W4308620412 cites W2058834304 @default.
- W4308620412 cites W2065461553 @default.
- W4308620412 cites W2070882281 @default.
- W4308620412 cites W2073270449 @default.
- W4308620412 cites W2073417188 @default.
- W4308620412 cites W2076722802 @default.
- W4308620412 cites W2081104568 @default.
- W4308620412 cites W2083651366 @default.
- W4308620412 cites W2083885449 @default.
- W4308620412 cites W2085544302 @default.
- W4308620412 cites W2086081812 @default.
- W4308620412 cites W2092931526 @default.
- W4308620412 cites W2099367992 @default.
- W4308620412 cites W2104696612 @default.
- W4308620412 cites W2105329815 @default.
- W4308620412 cites W2105817940 @default.
- W4308620412 cites W2106264290 @default.
- W4308620412 cites W2106556665 @default.
- W4308620412 cites W2108234281 @default.
- W4308620412 cites W2110335151 @default.
- W4308620412 cites W2112814753 @default.
- W4308620412 cites W2117260150 @default.
- W4308620412 cites W2118261313 @default.
- W4308620412 cites W2118503070 @default.
- W4308620412 cites W2118970397 @default.
- W4308620412 cites W2119041052 @default.
- W4308620412 cites W2119068792 @default.
- W4308620412 cites W2119311177 @default.
- W4308620412 cites W2122821321 @default.
- W4308620412 cites W2126419817 @default.
- W4308620412 cites W2126763484 @default.
- W4308620412 cites W2131271579 @default.
- W4308620412 cites W2131633033 @default.
- W4308620412 cites W2133579817 @default.
- W4308620412 cites W2134562606 @default.
- W4308620412 cites W2136434181 @default.
- W4308620412 cites W2140236604 @default.
- W4308620412 cites W2142678478 @default.
- W4308620412 cites W2146533600 @default.