FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4308634654> ?p ?o ?g. }

• W4308634654 endingPage "57" @default.
• W4308634654 startingPage "57" @default.
• W4308634654 abstract "Importance Evidence indicates that preexisting neuropsychiatric conditions confer increased risks of severe outcomes from COVID-19 infection. It is unclear how this increased risk compares with risks associated with other severe acute respiratory infections (SARIs). Objective To determine whether preexisting diagnosis of and/or treatment for a neuropsychiatric condition is associated with severe outcomes from COVID-19 infection and other SARIs and whether any observed association is similar between the 2 outcomes. Design, Setting, and Participants Prepandemic (2015-2020) and contemporary (2020-2021) longitudinal cohorts were derived from the QResearch database of English primary care records. Adjusted hazard ratios (HRs) with 99% CIs were estimated in April 2022 using flexible parametric survival models clustered by primary care clinic. This study included a population-based sample, including all adults in the database who had been registered with a primary care clinic for at least 1 year. Analysis of routinely collected primary care electronic medical records was performed. Exposures Diagnosis of and/or medication for anxiety, mood, or psychotic disorders and diagnosis of dementia, depression, schizophrenia, or bipolar disorder. Main Outcomes and Measures COVID-19–related mortality, or hospital or intensive care unit admission; SARI-related mortality, or hospital or intensive care unit admission. Results The prepandemic cohort comprised 11 134 789 adults (223 569 SARI cases [2.0%]) with a median (IQR) age of 42 (29-58) years, of which 5 644 525 (50.7%) were female. The contemporary cohort comprised 8 388 956 adults (58 203 severe COVID-19 cases [0.7%]) with a median (IQR) age of 48 (34-63) years, of which 4 207 192 were male (50.2%). Diagnosis and/or treatment for neuropsychiatric conditions other than dementia was associated with an increased likelihood of a severe outcome from SARI (anxiety diagnosis: HR, 1.16; 99% CI, 1.13-1.18; psychotic disorder diagnosis and treatment: HR, 2.56; 99% CI, 2.40-2.72) and COVID-19 (anxiety diagnosis: HR, 1.16; 99% CI, 1.12-1.20; psychotic disorder treatment: HR, 2.37; 99% CI, 2.20-2.55). The effect estimate for severe outcome with dementia was higher for those with COVID-19 than SARI (HR, 2.85; 99% CI, 2.71-3.00 vs HR, 2.13; 99% CI, 2.07-2.19). Conclusions and Relevance In this longitudinal cohort study, UK patients with preexisting neuropsychiatric conditions and treatments were associated with similarly increased risks of severe outcome from COVID-19 infection and SARIs, except for dementia." @default.
• W4308634654 created "2022-11-13" @default.
• W4308634654 creator A5004448187 @default.
• W4308634654 creator A5013117957 @default.
• W4308634654 creator A5022295783 @default.
• W4308634654 creator A5033672260 @default.
• W4308634654 creator A5038204850 @default.
• W4308634654 creator A5040265684 @default.
• W4308634654 creator A5071665894 @default.
• W4308634654 creator A5078701828 @default.
• W4308634654 date "2023-01-01" @default.
• W4308634654 modified "2023-09-30" @default.
• W4308634654 title "Preexisting Neuropsychiatric Conditions and Associated Risk of Severe COVID-19 Infection and Other Acute Respiratory Infections" @default.
• W4308634654 cites W1890103931 @default.
• W4308634654 cites W2064616280 @default.
• W4308634654 cites W2102094268 @default.
• W4308634654 cites W2129409351 @default.
• W4308634654 cites W2134843796 @default.
• W4308634654 cites W2161515661 @default.
• W4308634654 cites W2165493400 @default.
• W4308634654 cites W2303203998 @default.
• W4308634654 cites W2897918475 @default.
• W4308634654 cites W2958971346 @default.
• W4308634654 cites W3008443627 @default.
• W4308634654 cites W3033521180 @default.
• W4308634654 cites W3184107630 @default.
• W4308634654 cites W3186279334 @default.
• W4308634654 cites W3206861857 @default.
• W4308634654 cites W3208279890 @default.
• W4308634654 cites W3208556307 @default.
• W4308634654 cites W4210590233 @default.
• W4308634654 cites W4280549898 @default.
• W4308634654 cites W4294116629 @default.
• W4308634654 doi "https://doi.org/10.1001/jamapsychiatry.2022.3614" @default.
• W4308634654 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36350602" @default.
• W4308634654 hasPublicationYear "2023" @default.
• W4308634654 type Work @default.
• W4308634654 citedByCount "4" @default.
• W4308634654 countsByYear W43086346542023 @default.
• W4308634654 crossrefType "journal-article" @default.
• W4308634654 hasAuthorship W4308634654A5004448187 @default.
• W4308634654 hasAuthorship W4308634654A5013117957 @default.
• W4308634654 hasAuthorship W4308634654A5022295783 @default.
• W4308634654 hasAuthorship W4308634654A5033672260 @default.
• W4308634654 hasAuthorship W4308634654A5038204850 @default.
• W4308634654 hasAuthorship W4308634654A5040265684 @default.
• W4308634654 hasAuthorship W4308634654A5071665894 @default.
• W4308634654 hasAuthorship W4308634654A5078701828 @default.
• W4308634654 hasBestOaLocation W43086346541 @default.
• W4308634654 hasConcept C118552586 @default.
• W4308634654 hasConcept C126322002 @default.
• W4308634654 hasConcept C139719470 @default.
• W4308634654 hasConcept C162324750 @default.
• W4308634654 hasConcept C187212893 @default.
• W4308634654 hasConcept C194828623 @default.
• W4308634654 hasConcept C195910791 @default.
• W4308634654 hasConcept C201903717 @default.
• W4308634654 hasConcept C207103383 @default.
• W4308634654 hasConcept C2776174506 @default.
• W4308634654 hasConcept C2776376669 @default.
• W4308634654 hasConcept C2776867660 @default.
• W4308634654 hasConcept C2779134260 @default.
• W4308634654 hasConcept C2779483572 @default.
• W4308634654 hasConcept C2780733359 @default.
• W4308634654 hasConcept C2908647359 @default.
• W4308634654 hasConcept C44249647 @default.
• W4308634654 hasConcept C558461103 @default.
• W4308634654 hasConcept C71924100 @default.
• W4308634654 hasConcept C72563966 @default.
• W4308634654 hasConcept C99454951 @default.
• W4308634654 hasConceptScore W4308634654C118552586 @default.
• W4308634654 hasConceptScore W4308634654C126322002 @default.
• W4308634654 hasConceptScore W4308634654C139719470 @default.
• W4308634654 hasConceptScore W4308634654C162324750 @default.
• W4308634654 hasConceptScore W4308634654C187212893 @default.
• W4308634654 hasConceptScore W4308634654C194828623 @default.
• W4308634654 hasConceptScore W4308634654C195910791 @default.
• W4308634654 hasConceptScore W4308634654C201903717 @default.
• W4308634654 hasConceptScore W4308634654C207103383 @default.
• W4308634654 hasConceptScore W4308634654C2776174506 @default.
• W4308634654 hasConceptScore W4308634654C2776376669 @default.
• W4308634654 hasConceptScore W4308634654C2776867660 @default.
• W4308634654 hasConceptScore W4308634654C2779134260 @default.
• W4308634654 hasConceptScore W4308634654C2779483572 @default.
• W4308634654 hasConceptScore W4308634654C2780733359 @default.
• W4308634654 hasConceptScore W4308634654C2908647359 @default.
• W4308634654 hasConceptScore W4308634654C44249647 @default.
• W4308634654 hasConceptScore W4308634654C558461103 @default.
• W4308634654 hasConceptScore W4308634654C71924100 @default.
• W4308634654 hasConceptScore W4308634654C72563966 @default.
• W4308634654 hasConceptScore W4308634654C99454951 @default.
• W4308634654 hasIssue "1" @default.
• W4308634654 hasLocation W43086346541 @default.
• W4308634654 hasLocation W43086346542 @default.
• W4308634654 hasLocation W43086346543 @default.
• W4308634654 hasLocation W43086346544 @default.
• W4308634654 hasLocation W43086346545 @default.
• W4308634654 hasLocation W43086346546 @default.

• next