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- W4308656818 abstract "In this work, a novel conjugated microporous polymer on carbon nanotube composite (CMP-CNTs) was synthesized as photoelectrochemical (PEC) signal probe to construct sensitive PEC biosensor for sensing N-Gene of COVID-19 by integrating with an ingenious target-trigger T-junction recycling dual-strand displacement amplification (T-DSDA). The CMP-CNTs composites has an ideal photoelectrical conversion efficiency owing to the appearance of a good band matching that can effectively promote electron-hole pairs separation and accelerate carrier migration, thereby generating an extremely high initial photocurrent. Meanwhile, the T-DSDA with superior target conversion efficiency to traditional approaches could convert the small number of targets into extensive output DNAs, leading to the in-situ generation of quench agent N-GQDS decorated nanowires on electrode for significantly reducing initial photocurrent. The results demonstrated that proposed PEC biosensor had a high sensitivity towards N-Gene of COVID-19 and the detection limit was 33 aM, which provided a new way to build the simple, sensitive, and reliable sensing platform for great potential in biological analysis and early clinical diagnosis. • New CMP-CNTs composites have a good energy band matching, which can boost visible light absorption efficiency. • A target-trigger T-junction dual-strand displacement amplification transform small targets into massive output DNAs. • Output DNAs trigger HCR to generate N-GQDs modified nanowires in situ, which significantly reduces the PEC signal. • The proposed PEC biosensor of CMP-CNTs composites achieved ultra-sensitive detection of N-Gene of COVID-19." @default.
- W4308656818 created "2022-11-13" @default.
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- W4308656818 date "2023-02-01" @default.
- W4308656818 modified "2023-10-18" @default.
- W4308656818 title "Photoactive conjugated microporous polymer/carbon nanotube coupled with T-junction recycling dual-strand displacement amplification for sensing N-Gene of COVID-19" @default.
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- W4308656818 doi "https://doi.org/10.1016/j.snb.2022.132974" @default.
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