FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4308678857> ?p ?o ?g. }

• W4308678857 abstract "Abstract In shotgun metagenomics (SM), the state-of-the-art bioinformatic workflows are referred to as high-resolution shotgun metagenomics (HRSM) and require intensive computing and disk storage resources. While the increase in data output of the latest iteration of high-throughput DNA sequencing systems can allow for unprecedented sequencing depth at a minimal cost, adjustments in HRSM workflows will be needed to properly process these ever-increasing sequence datasets. One potential adaptation is to generate so-called shallow SM datasets that contain fewer sequencing data per sample as compared with the more classic high coverage sequencing. While shallow sequencing is a promising avenue for SM data analysis, detailed benchmarks using real-data are lacking. In this case study, we took four public SM datasets, one massive and the others moderate in size and subsampled each dataset at various levels to mimic shallow sequencing datasets of various sequencing depths. Our results suggest that shallow SM sequencing is a viable avenue to obtain sound results regarding microbial community structures and that high-depth sequencing does not bring additional elements for ecological interpretation. More specifically, results obtained by subsampling as little as 0.5 M sequencing clusters per sample were similar to the results obtained with the largest subsampled dataset for human gut and agricultural soil datasets. For an Antarctic dataset, which contained only a few samples, 4 M sequencing clusters per sample was found to generate comparable results to the full dataset. One area where ultra-deep sequencing and maximizing the usage of all data was undeniably beneficial was in the generation of metagenome-assembled genomes." @default.
• W4308678857 created "2022-11-14" @default.
• W4308678857 creator A5020050392 @default.
• W4308678857 creator A5029981243 @default.
• W4308678857 creator A5055235252 @default.
• W4308678857 date "2022-10-30" @default.
• W4308678857 modified "2023-09-23" @default.
• W4308678857 title "High-resolution shotgun metagenomics: the more data, the better?" @default.
• W4308678857 cites W1584790813 @default.
• W4308678857 cites W1878521557 @default.
• W4308678857 cites W1984284869 @default.
• W4308678857 cites W2009027589 @default.
• W4308678857 cites W2010002522 @default.
• W4308678857 cites W2031303523 @default.
• W4308678857 cites W2072841531 @default.
• W4308678857 cites W2097550077 @default.
• W4308678857 cites W2102619694 @default.
• W4308678857 cites W2103336148 @default.
• W4308678857 cites W2108234281 @default.
• W4308678857 cites W2112364185 @default.
• W4308678857 cites W2113679889 @default.
• W4308678857 cites W2131271579 @default.
• W4308678857 cites W2132842643 @default.
• W4308678857 cites W2134675370 @default.
• W4308678857 cites W2135780060 @default.
• W4308678857 cites W2136632285 @default.
• W4308678857 cites W2142678478 @default.
• W4308678857 cites W2143485490 @default.
• W4308678857 cites W2599417231 @default.
• W4308678857 cites W2605088440 @default.
• W4308678857 cites W2744725584 @default.
• W4308678857 cites W2758005814 @default.
• W4308678857 cites W2773939681 @default.
• W4308678857 cites W2949355358 @default.
• W4308678857 cites W2951076599 @default.
• W4308678857 cites W2969718750 @default.
• W4308678857 cites W2979777307 @default.
• W4308678857 cites W3003746554 @default.
• W4308678857 cites W3009062903 @default.
• W4308678857 cites W3027189408 @default.
• W4308678857 cites W3113153648 @default.
• W4308678857 cites W3143063265 @default.
• W4308678857 cites W3217463608 @default.
• W4308678857 cites W4294216483 @default.
• W4308678857 doi "https://doi.org/10.1093/bib/bbac443" @default.
• W4308678857 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36352504" @default.
• W4308678857 hasPublicationYear "2022" @default.
• W4308678857 type Work @default.
• W4308678857 citedByCount "2" @default.
• W4308678857 countsByYear W43086788572023 @default.
• W4308678857 crossrefType "journal-article" @default.
• W4308678857 hasAuthorship W4308678857A5020050392 @default.
• W4308678857 hasAuthorship W4308678857A5029981243 @default.
• W4308678857 hasAuthorship W4308678857A5055235252 @default.
• W4308678857 hasBestOaLocation W43086788572 @default.
• W4308678857 hasConcept C101985253 @default.
• W4308678857 hasConcept C104317684 @default.
• W4308678857 hasConcept C106337198 @default.
• W4308678857 hasConcept C124101348 @default.
• W4308678857 hasConcept C132917006 @default.
• W4308678857 hasConcept C141231307 @default.
• W4308678857 hasConcept C150194340 @default.
• W4308678857 hasConcept C15151743 @default.
• W4308678857 hasConcept C162317418 @default.
• W4308678857 hasConcept C177212765 @default.
• W4308678857 hasConcept C185592680 @default.
• W4308678857 hasConcept C18949551 @default.
• W4308678857 hasConcept C198531522 @default.
• W4308678857 hasConcept C2781434637 @default.
• W4308678857 hasConcept C41008148 @default.
• W4308678857 hasConcept C43617362 @default.
• W4308678857 hasConcept C51679486 @default.
• W4308678857 hasConcept C54355233 @default.
• W4308678857 hasConcept C70721500 @default.
• W4308678857 hasConcept C77088390 @default.
• W4308678857 hasConcept C86803240 @default.
• W4308678857 hasConceptScore W4308678857C101985253 @default.
• W4308678857 hasConceptScore W4308678857C104317684 @default.
• W4308678857 hasConceptScore W4308678857C106337198 @default.
• W4308678857 hasConceptScore W4308678857C124101348 @default.
• W4308678857 hasConceptScore W4308678857C132917006 @default.
• W4308678857 hasConceptScore W4308678857C141231307 @default.
• W4308678857 hasConceptScore W4308678857C150194340 @default.
• W4308678857 hasConceptScore W4308678857C15151743 @default.
• W4308678857 hasConceptScore W4308678857C162317418 @default.
• W4308678857 hasConceptScore W4308678857C177212765 @default.
• W4308678857 hasConceptScore W4308678857C185592680 @default.
• W4308678857 hasConceptScore W4308678857C18949551 @default.
• W4308678857 hasConceptScore W4308678857C198531522 @default.
• W4308678857 hasConceptScore W4308678857C2781434637 @default.
• W4308678857 hasConceptScore W4308678857C41008148 @default.
• W4308678857 hasConceptScore W4308678857C43617362 @default.
• W4308678857 hasConceptScore W4308678857C51679486 @default.
• W4308678857 hasConceptScore W4308678857C54355233 @default.
• W4308678857 hasConceptScore W4308678857C70721500 @default.
• W4308678857 hasConceptScore W4308678857C77088390 @default.
• W4308678857 hasConceptScore W4308678857C86803240 @default.
• W4308678857 hasIssue "6" @default.
• W4308678857 hasLocation W43086788571 @default.
• W4308678857 hasLocation W43086788572 @default.

• next