Matches in SemOpenAlex for { <https://semopenalex.org/work/W4308678879> ?p ?o ?g. }
- W4308678879 abstract "Little is known about risk factors for mortality in older patients with COVID-19 and neuropsychiatric conditions.We conducted a multicentric retrospective observational study at Assistance Publique-Hôpitaux de Paris. We selected inpatients aged 70 years or older, with COVID-19 and preexisting neuropsychiatric comorbidities and/or new neuropsychiatric manifestations. We examined demographics, comorbidities, functional status, and presentation including neuropsychiatric symptoms and disorders, as well as paraclinical data. Cox survival analysis was conducted to determine risk factors for mortality at 40 days after the first symptoms of COVID-19.Out of 191 patients included (median age 80 [interquartile range 74-87]), 135 (71%) had neuropsychiatric comorbidities including cognitive impairment (39%), cerebrovascular disease (22%), Parkinsonism (6%), and brain tumors (6%). A total of 152 (79%) patients presented new-onset neuropsychiatric manifestations including sensory symptoms (6%), motor deficit (11%), behavioral (18%) and cognitive (23%) disturbances, gait impairment (11%), and impaired consciousness (18%). The mortality rate at 40 days was 19.4%. A history of brain tumor or Parkinsonism or the occurrence of impaired consciousness were neurological factors associated with a higher risk of mortality. A lower Activities of Daily Living score (hazard ratio [HR] 0.69, 95% confidence interval [CI] 0.58-0.82), a neutrophil-to-lymphocyte ratio ≥ 9.9 (HR 5.69, 95% CI 2.69-12.0), and thrombocytopenia (HR 5.70, 95% CI 2.75-11.8) independently increased the risk of mortality (all p < .001).Understanding mortality risk factors in older inpatients with COVID-19 and neuropsychiatric conditions may be helpful to neurologists and geriatricians who manage these patients in clinical practice." @default.
- W4308678879 created "2022-11-14" @default.
- W4308678879 creator A5003165737 @default.
- W4308678879 creator A5005919591 @default.
- W4308678879 creator A5010557467 @default.
- W4308678879 creator A5014013424 @default.
- W4308678879 creator A5014607338 @default.
- W4308678879 creator A5018122144 @default.
- W4308678879 creator A5020961970 @default.
- W4308678879 creator A5025192399 @default.
- W4308678879 creator A5028943469 @default.
- W4308678879 creator A5036507581 @default.
- W4308678879 creator A5037380888 @default.
- W4308678879 creator A5037983714 @default.
- W4308678879 creator A5043578217 @default.
- W4308678879 creator A5054788080 @default.
- W4308678879 creator A5056717737 @default.
- W4308678879 creator A5060316910 @default.
- W4308678879 creator A5063384332 @default.
- W4308678879 creator A5065531665 @default.
- W4308678879 creator A5068151393 @default.
- W4308678879 creator A5070914037 @default.
- W4308678879 creator A5074578462 @default.
- W4308678879 creator A5078390423 @default.
- W4308678879 creator A5083589275 @default.
- W4308678879 creator A5089202815 @default.
- W4308678879 date "2022-11-10" @default.
- W4308678879 modified "2023-10-09" @default.
- W4308678879 title "Older patients with COVID‐19 and neuropsychiatric conditions: A study of risk factors for mortality" @default.
- W4308678879 cites W2081743406 @default.
- W4308678879 cites W2141710162 @default.
- W4308678879 cites W2164186760 @default.
- W4308678879 cites W3005686380 @default.
- W4308678879 cites W3014275885 @default.
- W4308678879 cites W3014282324 @default.
- W4308678879 cites W3016124709 @default.
- W4308678879 cites W3016127017 @default.
- W4308678879 cites W3016243206 @default.
- W4308678879 cites W3016535995 @default.
- W4308678879 cites W3023752426 @default.
- W4308678879 cites W3024193040 @default.
- W4308678879 cites W3026764413 @default.
- W4308678879 cites W3030998798 @default.
- W4308678879 cites W3031634823 @default.
- W4308678879 cites W3033708621 @default.
- W4308678879 cites W3033725686 @default.
- W4308678879 cites W3036360906 @default.
- W4308678879 cites W3041582510 @default.
- W4308678879 cites W3042206791 @default.
- W4308678879 cites W3043240332 @default.
- W4308678879 cites W3045791048 @default.
- W4308678879 cites W3048497432 @default.
- W4308678879 cites W3081101061 @default.
- W4308678879 cites W3084138038 @default.
- W4308678879 cites W3085629533 @default.
- W4308678879 cites W3087089442 @default.
- W4308678879 cites W3088554120 @default.
- W4308678879 cites W3089162980 @default.
- W4308678879 cites W3091466380 @default.
- W4308678879 cites W3091932000 @default.
- W4308678879 cites W3093103869 @default.
- W4308678879 cites W3093681324 @default.
- W4308678879 cites W3095700519 @default.
- W4308678879 cites W3102940835 @default.
- W4308678879 cites W3104241090 @default.
- W4308678879 cites W3105977391 @default.
- W4308678879 cites W3110517956 @default.
- W4308678879 cites W3113728430 @default.
- W4308678879 cites W3119190148 @default.
- W4308678879 cites W3122763335 @default.
- W4308678879 cites W3123073077 @default.
- W4308678879 cites W3125923246 @default.
- W4308678879 cites W3131543649 @default.
- W4308678879 cites W3136076967 @default.
- W4308678879 cites W3157407274 @default.
- W4308678879 cites W3163573320 @default.
- W4308678879 cites W3177021448 @default.
- W4308678879 cites W3177135130 @default.
- W4308678879 cites W4210575617 @default.
- W4308678879 cites W4284691082 @default.
- W4308678879 cites W4308678879 @default.
- W4308678879 doi "https://doi.org/10.1002/brb3.2787" @default.
- W4308678879 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36355411" @default.
- W4308678879 hasPublicationYear "2022" @default.
- W4308678879 type Work @default.
- W4308678879 citedByCount "1" @default.
- W4308678879 countsByYear W43086788792022 @default.
- W4308678879 crossrefType "journal-article" @default.
- W4308678879 hasAuthorship W4308678879A5003165737 @default.
- W4308678879 hasAuthorship W4308678879A5005919591 @default.
- W4308678879 hasAuthorship W4308678879A5010557467 @default.
- W4308678879 hasAuthorship W4308678879A5014013424 @default.
- W4308678879 hasAuthorship W4308678879A5014607338 @default.
- W4308678879 hasAuthorship W4308678879A5018122144 @default.
- W4308678879 hasAuthorship W4308678879A5020961970 @default.
- W4308678879 hasAuthorship W4308678879A5025192399 @default.
- W4308678879 hasAuthorship W4308678879A5028943469 @default.
- W4308678879 hasAuthorship W4308678879A5036507581 @default.
- W4308678879 hasAuthorship W4308678879A5037380888 @default.
- W4308678879 hasAuthorship W4308678879A5037983714 @default.