Matches in SemOpenAlex for { <https://semopenalex.org/work/W4308682726> ?p ?o ?g. }
- W4308682726 endingPage "577" @default.
- W4308682726 startingPage "563" @default.
- W4308682726 abstract "Abstract Cancer is frequently caused by microRNAs, which control post-transcriptional levels of gene expression by binding to target mRNAs. MiR-29a-3p has recently been shown to play a twofold function in the majority of malignancies, including colorectal cancer (CRC), according to mounting evidence. Here, we not only briefly summarize such connection between miR-29a-3p and cancers, but aslo primarily evaluate the miR-29a-3p expression pattern, clinical applicability, and molecular mechanisms in CRC to provide a guide for future studies. This review established the diagnostic and prognostic value of miR-29a-3p abnormalty in a variety of clinical samples for CRC. Furthermore, current molecular mechanisms of miR-29a-3p for regulating cancerous biological processes such growth, invasion, metastasis, the epithelial-mesenchymal transformation process, and immunomodulation through its upstream regulatory factors and downstream targeted genes were briefly explored. More specifically, miR-29a-3p has been linked to a few medications that have been shown to have anticancer benefits. To sum up, miR-29a-3p is a promising biomarker and prospective therapeutic target for the diagnosis and prognosis of CRC, but further research is still needed to establish a theoretical basis for more practical applications." @default.
- W4308682726 created "2022-11-14" @default.
- W4308682726 creator A5008323548 @default.
- W4308682726 creator A5026229992 @default.
- W4308682726 date "2022-11-10" @default.
- W4308682726 modified "2023-09-30" @default.
- W4308682726 title "MiR-29a-3p: a potential biomarker and therapeutic target in colorectal cancer" @default.
- W4308682726 cites W1496125310 @default.
- W4308682726 cites W1939801702 @default.
- W4308682726 cites W1977499057 @default.
- W4308682726 cites W2002168324 @default.
- W4308682726 cites W2020218669 @default.
- W4308682726 cites W2028405970 @default.
- W4308682726 cites W2037764834 @default.
- W4308682726 cites W2061873339 @default.
- W4308682726 cites W2106872445 @default.
- W4308682726 cites W2140245250 @default.
- W4308682726 cites W2151922790 @default.
- W4308682726 cites W2207249673 @default.
- W4308682726 cites W2302294892 @default.
- W4308682726 cites W2505777705 @default.
- W4308682726 cites W2511791622 @default.
- W4308682726 cites W2530597079 @default.
- W4308682726 cites W2538219826 @default.
- W4308682726 cites W2575972759 @default.
- W4308682726 cites W2722972730 @default.
- W4308682726 cites W2746167674 @default.
- W4308682726 cites W2766101922 @default.
- W4308682726 cites W2772251059 @default.
- W4308682726 cites W2775490195 @default.
- W4308682726 cites W2791017655 @default.
- W4308682726 cites W2811212358 @default.
- W4308682726 cites W2884620854 @default.
- W4308682726 cites W2884924251 @default.
- W4308682726 cites W2902910704 @default.
- W4308682726 cites W2904001470 @default.
- W4308682726 cites W2907368400 @default.
- W4308682726 cites W2907841219 @default.
- W4308682726 cites W2917523924 @default.
- W4308682726 cites W2917793200 @default.
- W4308682726 cites W2919470997 @default.
- W4308682726 cites W2926329633 @default.
- W4308682726 cites W2943065011 @default.
- W4308682726 cites W2945552786 @default.
- W4308682726 cites W2947308059 @default.
- W4308682726 cites W2962456910 @default.
- W4308682726 cites W2964205044 @default.
- W4308682726 cites W2969760752 @default.
- W4308682726 cites W2971482366 @default.
- W4308682726 cites W2979426395 @default.
- W4308682726 cites W2980428282 @default.
- W4308682726 cites W2980713719 @default.
- W4308682726 cites W2982703497 @default.
- W4308682726 cites W2983012175 @default.
- W4308682726 cites W2984750061 @default.
- W4308682726 cites W2988290061 @default.
- W4308682726 cites W2990671219 @default.
- W4308682726 cites W2994717720 @default.
- W4308682726 cites W2996541033 @default.
- W4308682726 cites W3001373407 @default.
- W4308682726 cites W3007058700 @default.
- W4308682726 cites W3016052681 @default.
- W4308682726 cites W3019924743 @default.
- W4308682726 cites W3025118672 @default.
- W4308682726 cites W3036439734 @default.
- W4308682726 cites W3080501427 @default.
- W4308682726 cites W3084224551 @default.
- W4308682726 cites W3090904852 @default.
- W4308682726 cites W3094313403 @default.
- W4308682726 cites W3096184791 @default.
- W4308682726 cites W3096223133 @default.
- W4308682726 cites W3099616110 @default.
- W4308682726 cites W3108614647 @default.
- W4308682726 cites W3115272251 @default.
- W4308682726 cites W3120528701 @default.
- W4308682726 cites W3126619638 @default.
- W4308682726 cites W3127062995 @default.
- W4308682726 cites W3127351960 @default.
- W4308682726 cites W3134297887 @default.
- W4308682726 cites W3135968019 @default.
- W4308682726 cites W3158562287 @default.
- W4308682726 cites W3159035683 @default.
- W4308682726 cites W3163289793 @default.
- W4308682726 cites W3164918238 @default.
- W4308682726 cites W3168954898 @default.
- W4308682726 cites W3171041751 @default.
- W4308682726 cites W3180063226 @default.
- W4308682726 cites W3185123221 @default.
- W4308682726 cites W3185571211 @default.
- W4308682726 cites W3196321074 @default.
- W4308682726 cites W3207845424 @default.
- W4308682726 cites W4205395271 @default.
- W4308682726 cites W4206457155 @default.
- W4308682726 cites W4210563261 @default.
- W4308682726 cites W4210602467 @default.
- W4308682726 cites W4214945357 @default.
- W4308682726 cites W4223470054 @default.
- W4308682726 cites W4223582594 @default.