Matches in SemOpenAlex for { <https://semopenalex.org/work/W4308683708> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W4308683708 endingPage "1207" @default.
- W4308683708 startingPage "1201" @default.
- W4308683708 abstract "Candida species cause the most prevalent fungal illness, candidiasis. Candida albicans is known to cause bloodstream infections. This species is a commensal bacterium, but it can cause hospital-acquired diseases, particularly in COVID-19 patients with impaired immune systems. Candida infections have increased in patients with acute respiratory distress syndrome. Coumarins are both naturally occurring and synthetically produced. In this study, the biological activity of 40 coumarin derivatives was used to create a three-dimensional quantitative structure activity relationship (3D-QSAR) model. The training and test minimum inhibitory concentration values of C. albicans active compounds were split, and a regression model based on statistical data was established. This model served as a foundation for the creation of coumarin derivative QSARs. This is a unique way to create new therapeutic compounds for various ailments. We constructed novel structural coumarin derivatives using the derived QSAR model, and the models were confirmed using molecular docking and molecular dynamics simulation." @default.
- W4308683708 created "2022-11-14" @default.
- W4308683708 creator A5010247793 @default.
- W4308683708 creator A5030784506 @default.
- W4308683708 date "2022-11-10" @default.
- W4308683708 modified "2023-10-01" @default.
- W4308683708 title "Coumarin-based combined computational study to design novel drugs against Candida albicans" @default.
- W4308683708 cites W1999491936 @default.
- W4308683708 cites W2000400913 @default.
- W4308683708 cites W2041791898 @default.
- W4308683708 cites W2055222716 @default.
- W4308683708 cites W2080289165 @default.
- W4308683708 cites W2089477767 @default.
- W4308683708 cites W2092719433 @default.
- W4308683708 cites W2107013040 @default.
- W4308683708 cites W2109154308 @default.
- W4308683708 cites W2118236446 @default.
- W4308683708 cites W2125123409 @default.
- W4308683708 cites W2128128747 @default.
- W4308683708 cites W2163358892 @default.
- W4308683708 cites W2163758697 @default.
- W4308683708 cites W2170764510 @default.
- W4308683708 cites W2535518633 @default.
- W4308683708 cites W2921098500 @default.
- W4308683708 cites W2954362930 @default.
- W4308683708 cites W3002108456 @default.
- W4308683708 cites W3036214010 @default.
- W4308683708 cites W3081234543 @default.
- W4308683708 cites W3123290442 @default.
- W4308683708 cites W3123997054 @default.
- W4308683708 cites W3144145499 @default.
- W4308683708 cites W4292513117 @default.
- W4308683708 doi "https://doi.org/10.1007/s12275-022-2279-5" @default.
- W4308683708 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36355278" @default.
- W4308683708 hasPublicationYear "2022" @default.
- W4308683708 type Work @default.
- W4308683708 citedByCount "2" @default.
- W4308683708 countsByYear W43086837082023 @default.
- W4308683708 crossrefType "journal-article" @default.
- W4308683708 hasAuthorship W4308683708A5010247793 @default.
- W4308683708 hasAuthorship W4308683708A5030784506 @default.
- W4308683708 hasBestOaLocation W43086837081 @default.
- W4308683708 hasConcept C145081991 @default.
- W4308683708 hasConcept C164126121 @default.
- W4308683708 hasConcept C178790620 @default.
- W4308683708 hasConcept C185592680 @default.
- W4308683708 hasConcept C2780917455 @default.
- W4308683708 hasConcept C2781338262 @default.
- W4308683708 hasConcept C71240020 @default.
- W4308683708 hasConcept C86803240 @default.
- W4308683708 hasConcept C89423630 @default.
- W4308683708 hasConceptScore W4308683708C145081991 @default.
- W4308683708 hasConceptScore W4308683708C164126121 @default.
- W4308683708 hasConceptScore W4308683708C178790620 @default.
- W4308683708 hasConceptScore W4308683708C185592680 @default.
- W4308683708 hasConceptScore W4308683708C2780917455 @default.
- W4308683708 hasConceptScore W4308683708C2781338262 @default.
- W4308683708 hasConceptScore W4308683708C71240020 @default.
- W4308683708 hasConceptScore W4308683708C86803240 @default.
- W4308683708 hasConceptScore W4308683708C89423630 @default.
- W4308683708 hasIssue "12" @default.
- W4308683708 hasLocation W43086837081 @default.
- W4308683708 hasLocation W43086837082 @default.
- W4308683708 hasLocation W43086837083 @default.
- W4308683708 hasOpenAccess W4308683708 @default.
- W4308683708 hasPrimaryLocation W43086837081 @default.
- W4308683708 hasRelatedWork W2102861863 @default.
- W4308683708 hasRelatedWork W2128291007 @default.
- W4308683708 hasRelatedWork W2298392156 @default.
- W4308683708 hasRelatedWork W2888350538 @default.
- W4308683708 hasRelatedWork W2946449973 @default.
- W4308683708 hasRelatedWork W2966710179 @default.
- W4308683708 hasRelatedWork W3092085651 @default.
- W4308683708 hasRelatedWork W4297252087 @default.
- W4308683708 hasRelatedWork W4300690271 @default.
- W4308683708 hasRelatedWork W4308683708 @default.
- W4308683708 hasVolume "60" @default.
- W4308683708 isParatext "false" @default.
- W4308683708 isRetracted "false" @default.
- W4308683708 workType "article" @default.