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- W4308683902 endingPage "1044" @default.
- W4308683902 startingPage "1031" @default.
- W4308683902 abstract "Introduction Patients with cirrhosis are at risk of both thrombotic and hemorrhagic events. Traditional hemostatic tests are inadequate to assess the complex and fragile balance of hemostasis in this setting, especially in advanced stages of disease such as decompensated cirrhosis or acute on chronic liver failure (ACLF). Furthermore, the indiscriminate use of pro-hemostatic agents for prophylaxis and treatment of bleeding episodes is still debated and often contraindicated. Alongside, splanchnic, and peripheral thrombotic events are frequent in this population and require management that involves a careful balance between risks and benefits of antithrombotic therapy.Areas covered This review aims to address the state of the art on the clinical management of the hemostatic balance of cirrhosis in terms of established knowledge and future challenges.Expert opinion The old paradigm of cirrhosis as a naturally anticoagulated condition has been challenged by more sophisticated global tests of hemostasis. Integrating this information in the clinical decision-making is still challenging for physicians and experts in hemostasis." @default.
- W4308683902 created "2022-11-14" @default.
- W4308683902 creator A5004779104 @default.
- W4308683902 creator A5028671796 @default.
- W4308683902 creator A5088326019 @default.
- W4308683902 date "2022-11-09" @default.
- W4308683902 modified "2023-10-18" @default.
- W4308683902 title "Rational hemostatic management in cirrhosis: from old paradigms to new clinical challenges" @default.
- W4308683902 cites W1524658408 @default.
- W4308683902 cites W1560433166 @default.
- W4308683902 cites W1837090086 @default.
- W4308683902 cites W1895011641 @default.
- W4308683902 cites W1923113404 @default.
- W4308683902 cites W1934397638 @default.
- W4308683902 cites W1936977750 @default.
- W4308683902 cites W1970269083 @default.
- W4308683902 cites W1975552718 @default.
- W4308683902 cites W1977808059 @default.
- W4308683902 cites W1978745785 @default.
- W4308683902 cites W1981638958 @default.
- W4308683902 cites W1986547366 @default.
- W4308683902 cites W1987880263 @default.
- W4308683902 cites W1988170399 @default.
- W4308683902 cites W1988558621 @default.
- W4308683902 cites W1992235530 @default.
- W4308683902 cites W1992618503 @default.
- W4308683902 cites W1993340951 @default.
- W4308683902 cites W1993483465 @default.
- W4308683902 cites W1993708319 @default.
- W4308683902 cites W1995491984 @default.
- W4308683902 cites W1995608256 @default.
- W4308683902 cites W2000305246 @default.
- W4308683902 cites W2001252115 @default.
- W4308683902 cites W2002767954 @default.
- W4308683902 cites W2008407988 @default.
- W4308683902 cites W2009594394 @default.
- W4308683902 cites W2011557656 @default.
- W4308683902 cites W2011826456 @default.
- W4308683902 cites W2023532300 @default.
- W4308683902 cites W2028955938 @default.
- W4308683902 cites W2029143903 @default.
- W4308683902 cites W2032537572 @default.
- W4308683902 cites W2032693555 @default.
- W4308683902 cites W2032929309 @default.
- W4308683902 cites W2040826870 @default.
- W4308683902 cites W2041665223 @default.
- W4308683902 cites W2043539706 @default.
- W4308683902 cites W2060380869 @default.
- W4308683902 cites W2069243984 @default.
- W4308683902 cites W2076636814 @default.
- W4308683902 cites W2077466914 @default.
- W4308683902 cites W2078378195 @default.
- W4308683902 cites W2083256952 @default.
- W4308683902 cites W2090354111 @default.
- W4308683902 cites W2093338681 @default.
- W4308683902 cites W2095982855 @default.
- W4308683902 cites W2096230132 @default.
- W4308683902 cites W2096334834 @default.
- W4308683902 cites W2100118997 @default.
- W4308683902 cites W2100820094 @default.
- W4308683902 cites W2105599119 @default.
- W4308683902 cites W2107522704 @default.
- W4308683902 cites W2108532099 @default.
- W4308683902 cites W2113263213 @default.
- W4308683902 cites W2113917646 @default.
- W4308683902 cites W2119768870 @default.
- W4308683902 cites W2120144414 @default.
- W4308683902 cites W2121915918 @default.
- W4308683902 cites W2132426480 @default.
- W4308683902 cites W2135283537 @default.
- W4308683902 cites W2135361119 @default.
- W4308683902 cites W2137727365 @default.
- W4308683902 cites W2141634544 @default.
- W4308683902 cites W2144999545 @default.
- W4308683902 cites W2145791480 @default.
- W4308683902 cites W2146239485 @default.
- W4308683902 cites W2146292166 @default.
- W4308683902 cites W2147368252 @default.
- W4308683902 cites W2151886152 @default.
- W4308683902 cites W2153267472 @default.
- W4308683902 cites W2166018647 @default.
- W4308683902 cites W2168749349 @default.
- W4308683902 cites W2170591435 @default.
- W4308683902 cites W2170740817 @default.
- W4308683902 cites W2178972472 @default.
- W4308683902 cites W2188275226 @default.
- W4308683902 cites W2204728067 @default.
- W4308683902 cites W2256275932 @default.
- W4308683902 cites W2274569134 @default.
- W4308683902 cites W2278397630 @default.
- W4308683902 cites W2285663224 @default.
- W4308683902 cites W2317603982 @default.
- W4308683902 cites W2319085829 @default.
- W4308683902 cites W2328176302 @default.
- W4308683902 cites W2336050472 @default.
- W4308683902 cites W2344515048 @default.
- W4308683902 cites W2400908595 @default.
- W4308683902 cites W2407179889 @default.