Matches in SemOpenAlex for { <https://semopenalex.org/work/W4308685957> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W4308685957 endingPage "28" @default.
- W4308685957 startingPage "21" @default.
- W4308685957 abstract "The literature regarding the neuropathological findings in cases of SARS-CoV-2 infection, which causes coronavirus disease 2019 (COVID-19), is expanding. We identified 72 patients who died of COVID-19 (n = 48) or had recovered shortly before death (n = 24) and had autopsies performed at our institution (49 males, 23 females; median age at death 76.4 years, range: 0.0-95.0 years). Droplet digital polymerase chain reaction (ddPCR) for the detection of SARS-CoV-2 was performed (n = 58) in multiple brain regions. In cases the assay was successfully completed (n = 50), 98.0% were negative (n = 49) and 2% were indeterminate (n = 1). Most histologic findings were typical of the patient age demographic, such as neurodegenerative disease and arteriolosclerosis. A subset of cases demonstrated findings which may be associated with sequelae of critical illness. We identified 3 cases with destructive perivascular lesions with axonal injury, one of which also harbored perivascular demyelinating lesions. These rare cases may represent a parainfectious process versus sequelae of vascular injury. The lack of detectable SARS-CoV-2 by ddPCR or significant histologic evidence of direct infection suggests that active encephalitis is not a feature of COVID-19." @default.
- W4308685957 created "2022-11-14" @default.
- W4308685957 creator A5001477666 @default.
- W4308685957 creator A5003123865 @default.
- W4308685957 creator A5038581416 @default.
- W4308685957 creator A5057597403 @default.
- W4308685957 creator A5087940326 @default.
- W4308685957 date "2022-11-10" @default.
- W4308685957 modified "2023-10-18" @default.
- W4308685957 title "Neuropathological findings in COVID-19: an autopsy cohort" @default.
- W4308685957 cites W2022857700 @default.
- W4308685957 cites W2131607023 @default.
- W4308685957 cites W2195212233 @default.
- W4308685957 cites W2751417101 @default.
- W4308685957 cites W2795999744 @default.
- W4308685957 cites W3008595315 @default.
- W4308685957 cites W3016911319 @default.
- W4308685957 cites W3021862213 @default.
- W4308685957 cites W3027354145 @default.
- W4308685957 cites W3034032308 @default.
- W4308685957 cites W3035063822 @default.
- W4308685957 cites W3037542049 @default.
- W4308685957 cites W3037780552 @default.
- W4308685957 cites W3041859425 @default.
- W4308685957 cites W3046281341 @default.
- W4308685957 cites W3048100425 @default.
- W4308685957 cites W3048904217 @default.
- W4308685957 cites W3074796735 @default.
- W4308685957 cites W3080798526 @default.
- W4308685957 cites W3081375343 @default.
- W4308685957 cites W3083231193 @default.
- W4308685957 cites W3085448472 @default.
- W4308685957 cites W3090344202 @default.
- W4308685957 cites W3094176824 @default.
- W4308685957 cites W3157658764 @default.
- W4308685957 cites W3158770516 @default.
- W4308685957 cites W3163056168 @default.
- W4308685957 cites W3169748460 @default.
- W4308685957 cites W3170277560 @default.
- W4308685957 cites W3173710414 @default.
- W4308685957 cites W3175961346 @default.
- W4308685957 cites W3186079608 @default.
- W4308685957 cites W3197642133 @default.
- W4308685957 cites W3204706687 @default.
- W4308685957 cites W4205703637 @default.
- W4308685957 cites W4205788346 @default.
- W4308685957 cites W4210686331 @default.
- W4308685957 cites W4226098986 @default.
- W4308685957 cites W4229440959 @default.
- W4308685957 doi "https://doi.org/10.1093/jnen/nlac101" @default.
- W4308685957 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36355625" @default.
- W4308685957 hasPublicationYear "2022" @default.
- W4308685957 type Work @default.
- W4308685957 citedByCount "10" @default.
- W4308685957 countsByYear W43086859572023 @default.
- W4308685957 crossrefType "journal-article" @default.
- W4308685957 hasAuthorship W4308685957A5001477666 @default.
- W4308685957 hasAuthorship W4308685957A5003123865 @default.
- W4308685957 hasAuthorship W4308685957A5038581416 @default.
- W4308685957 hasAuthorship W4308685957A5057597403 @default.
- W4308685957 hasAuthorship W4308685957A5087940326 @default.
- W4308685957 hasConcept C142724271 @default.
- W4308685957 hasConcept C2779134260 @default.
- W4308685957 hasConcept C2779504383 @default.
- W4308685957 hasConcept C2780130745 @default.
- W4308685957 hasConcept C2780793064 @default.
- W4308685957 hasConcept C3007834351 @default.
- W4308685957 hasConcept C3008058167 @default.
- W4308685957 hasConcept C524204448 @default.
- W4308685957 hasConcept C71924100 @default.
- W4308685957 hasConceptScore W4308685957C142724271 @default.
- W4308685957 hasConceptScore W4308685957C2779134260 @default.
- W4308685957 hasConceptScore W4308685957C2779504383 @default.
- W4308685957 hasConceptScore W4308685957C2780130745 @default.
- W4308685957 hasConceptScore W4308685957C2780793064 @default.
- W4308685957 hasConceptScore W4308685957C3007834351 @default.
- W4308685957 hasConceptScore W4308685957C3008058167 @default.
- W4308685957 hasConceptScore W4308685957C524204448 @default.
- W4308685957 hasConceptScore W4308685957C71924100 @default.
- W4308685957 hasIssue "1" @default.
- W4308685957 hasLocation W43086859571 @default.
- W4308685957 hasLocation W43086859572 @default.
- W4308685957 hasOpenAccess W4308685957 @default.
- W4308685957 hasPrimaryLocation W43086859571 @default.
- W4308685957 hasRelatedWork W2122234393 @default.
- W4308685957 hasRelatedWork W2255894143 @default.
- W4308685957 hasRelatedWork W2771929031 @default.
- W4308685957 hasRelatedWork W3111552817 @default.
- W4308685957 hasRelatedWork W3176864053 @default.
- W4308685957 hasRelatedWork W3198183218 @default.
- W4308685957 hasRelatedWork W4205317059 @default.
- W4308685957 hasRelatedWork W4205810683 @default.
- W4308685957 hasRelatedWork W4206669628 @default.
- W4308685957 hasRelatedWork W4311787753 @default.
- W4308685957 hasVolume "82" @default.
- W4308685957 isParatext "false" @default.
- W4308685957 isRetracted "false" @default.
- W4308685957 workType "article" @default.