Matches in SemOpenAlex for { <https://semopenalex.org/work/W4308691370> ?p ?o ?g. }
- W4308691370 endingPage "107146" @default.
- W4308691370 startingPage "107146" @default.
- W4308691370 abstract "Under the large-scale breeding model, the performance of the Holstein bull is directly related to the economic efficiency of the whole dairy farm and is the key factor affecting the genetic quality of the herd. Although the number of reported studies on the association of long noncoding RNAs (lncRNAs) with male reproduction is increasing, there is a lack of research on how lncRNAs regulate Holstein bull testicular development and spermatogenesis. To explore the molecular mechanisms between lncRNAs and spermatogenesis, three 8-week-old Holstein bull (young bull, YB) testes and three 80-week-old Holstein bull (adult bull, AB) testes from the same herd were randomly chosen, and transcriptome analysis was performed to find associations between spermatogenesis and transcriptome profiles. About 16,956 differentially expressed lncRNAs (DELs) and 7970 differentially expressed mRNAs (DEMs) were identified, and 3642 significantly relationship pairs were screened out based on co-expression analysis. Further Hub analysis obtained 6 lncRNAs, and 71 mRNAs regulated by them were enriched subsequently. Functional analysis results of differentially expressed Hub LncRNA-mRNA pairs showed that more positive cell cycle checkpoints, spindle assembly and the sister chromatids separation in AB testes indicated higher production rates of sperm in AB as compared to YB. This study reveals physiological changes and further broaden our understanding of lncRNA regulation of spermatogenesis in the fully mature testis according to the transcriptome profiles." @default.
- W4308691370 created "2022-11-14" @default.
- W4308691370 creator A5009988205 @default.
- W4308691370 creator A5013203397 @default.
- W4308691370 creator A5023055507 @default.
- W4308691370 creator A5031628720 @default.
- W4308691370 creator A5038606050 @default.
- W4308691370 creator A5052761486 @default.
- W4308691370 creator A5064657543 @default.
- W4308691370 creator A5067390667 @default.
- W4308691370 date "2022-12-01" @default.
- W4308691370 modified "2023-10-18" @default.
- W4308691370 title "Identification of spermatogenesis-related lncRNA in Holstein bull testis after sexual maturity based on transcriptome analysis" @default.
- W4308691370 cites W2027847170 @default.
- W4308691370 cites W2057015734 @default.
- W4308691370 cites W2099211382 @default.
- W4308691370 cites W2102278945 @default.
- W4308691370 cites W2105026438 @default.
- W4308691370 cites W2142411839 @default.
- W4308691370 cites W2152239989 @default.
- W4308691370 cites W2290650939 @default.
- W4308691370 cites W2567255685 @default.
- W4308691370 cites W2607555575 @default.
- W4308691370 cites W2738767990 @default.
- W4308691370 cites W2790027006 @default.
- W4308691370 cites W2792572786 @default.
- W4308691370 cites W2887473550 @default.
- W4308691370 cites W2898104208 @default.
- W4308691370 cites W2942121684 @default.
- W4308691370 cites W2945292628 @default.
- W4308691370 cites W2954439798 @default.
- W4308691370 cites W2964849163 @default.
- W4308691370 cites W2965352872 @default.
- W4308691370 cites W2992337090 @default.
- W4308691370 cites W3018280931 @default.
- W4308691370 cites W3092670304 @default.
- W4308691370 cites W3095097220 @default.
- W4308691370 cites W3102445403 @default.
- W4308691370 cites W3111404439 @default.
- W4308691370 cites W3125546385 @default.
- W4308691370 cites W3134802544 @default.
- W4308691370 cites W3160134321 @default.
- W4308691370 cites W3160186015 @default.
- W4308691370 cites W3164258610 @default.
- W4308691370 cites W3193597980 @default.
- W4308691370 cites W3194917745 @default.
- W4308691370 cites W3202199062 @default.
- W4308691370 cites W4229704949 @default.
- W4308691370 cites W4283791007 @default.
- W4308691370 cites W4362060345 @default.
- W4308691370 doi "https://doi.org/10.1016/j.anireprosci.2022.107146" @default.
- W4308691370 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36371860" @default.
- W4308691370 hasPublicationYear "2022" @default.
- W4308691370 type Work @default.
- W4308691370 citedByCount "1" @default.
- W4308691370 countsByYear W43086913702023 @default.
- W4308691370 crossrefType "journal-article" @default.
- W4308691370 hasAuthorship W4308691370A5009988205 @default.
- W4308691370 hasAuthorship W4308691370A5013203397 @default.
- W4308691370 hasAuthorship W4308691370A5023055507 @default.
- W4308691370 hasAuthorship W4308691370A5031628720 @default.
- W4308691370 hasAuthorship W4308691370A5038606050 @default.
- W4308691370 hasAuthorship W4308691370A5052761486 @default.
- W4308691370 hasAuthorship W4308691370A5064657543 @default.
- W4308691370 hasAuthorship W4308691370A5067390667 @default.
- W4308691370 hasConcept C104317684 @default.
- W4308691370 hasConcept C123765429 @default.
- W4308691370 hasConcept C134018914 @default.
- W4308691370 hasConcept C140793950 @default.
- W4308691370 hasConcept C150194340 @default.
- W4308691370 hasConcept C162317418 @default.
- W4308691370 hasConcept C16685009 @default.
- W4308691370 hasConcept C194775826 @default.
- W4308691370 hasConcept C2781087480 @default.
- W4308691370 hasConcept C54355233 @default.
- W4308691370 hasConcept C71924100 @default.
- W4308691370 hasConcept C86803240 @default.
- W4308691370 hasConceptScore W4308691370C104317684 @default.
- W4308691370 hasConceptScore W4308691370C123765429 @default.
- W4308691370 hasConceptScore W4308691370C134018914 @default.
- W4308691370 hasConceptScore W4308691370C140793950 @default.
- W4308691370 hasConceptScore W4308691370C150194340 @default.
- W4308691370 hasConceptScore W4308691370C162317418 @default.
- W4308691370 hasConceptScore W4308691370C16685009 @default.
- W4308691370 hasConceptScore W4308691370C194775826 @default.
- W4308691370 hasConceptScore W4308691370C2781087480 @default.
- W4308691370 hasConceptScore W4308691370C54355233 @default.
- W4308691370 hasConceptScore W4308691370C71924100 @default.
- W4308691370 hasConceptScore W4308691370C86803240 @default.
- W4308691370 hasFunder F4320321001 @default.
- W4308691370 hasFunder F4320325927 @default.
- W4308691370 hasFunder F4320334010 @default.
- W4308691370 hasFunder F4320335429 @default.
- W4308691370 hasFunder F4320335848 @default.
- W4308691370 hasLocation W43086913701 @default.
- W4308691370 hasLocation W43086913702 @default.
- W4308691370 hasOpenAccess W4308691370 @default.
- W4308691370 hasPrimaryLocation W43086913701 @default.