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- W4308713045 abstract "Abstract Research on the contribution of the ipsilateral hemisphere to unilateral movements, and how it is mediated by transcallosal connections, has so far provided contradictory findings. By using Dynamic Causal Modelling (DCM) and Parametric Empirical Bayes (PEB) analyses applied to fMRI data, we sought to describe effective connectivity during executed and imagined right-hand grasping within the grasping network, namely the anterior intraparietal sulcus (aIPs), ventral (PMv) and dorsal (PMd) premotor cortex, supplementary motor area (SMA) and primary motor cortex (M1). The two-fold aim of the present work was to explore a) whether right and left parieto-frontal areas show similar connectivity couplings, and b) the interhemispheric dynamics between these regions across the two hemispheres. We detected a network architecture comparable across hemispheres during executed but not imagined grasping. Furthermore, during motor execution the interhemispheric crosstalk was mainly driven by premotor areas: we found an inhibitory influence from the right PMd toward the left premotor and motor areas and excitatory couplings between homologous ventral premotor and supplementary motor regions. Overall, our results support the view that dissociable components of unilateral grasping execution are encoded by a non-lateralized set of brain areas complexly intertwined by interhemispheric dynamics, whereas motor imagery obeys different principles." @default.
- W4308713045 created "2022-11-14" @default.
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- W4308713045 date "2022-11-10" @default.
- W4308713045 modified "2023-09-24" @default.
- W4308713045 title "Evaluating bridges across hemispheres: DCM reveals an interhemispheric interplay between the bilateral premotor cortex during grasping" @default.
- W4308713045 doi "https://doi.org/10.21203/rs.3.rs-2234029/v1" @default.
- W4308713045 hasPublicationYear "2022" @default.
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