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- W4308744020 abstract "Sickle cell disease (SCD) results in an inherited pattern of early morbidity and mortality for those affected, causing significant resource burdens on the healthcare system. Preimplantation genetic testing for monogenic diseases (PGT-M) uses next generation sequencing to identify unaffected embryos for transfer, allowing selection against genetically inherited disease processes. SCD, originating from a known single nucleotide point mutation, offers a precisely targeted opportunity for the use of PGT-M with highly sensitive and specific results." @default.
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- W4308744020 date "2022-11-01" @default.
- W4308744020 modified "2023-09-26" @default.
- W4308744020 title "PREIMPLANTATION GENETIC TESTING FOR SICKLE CELL DISEASE – A COST EFFECTIVENESS ANALYSIS" @default.
- W4308744020 doi "https://doi.org/10.1016/j.fertnstert.2022.09.262" @default.
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