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• W4308766045 endingPage "3770" @default.
• W4308766045 startingPage "3755" @default.
• W4308766045 abstract "D-amphetamine maintenance therapy is a promising strategy to reduce drug use in cocaine use disorder (addiction). In both male rats and human cocaine users, d-amphetamine treatment reduces cocaine-taking and -seeking. However, this has not been examined systematically in female animals, even though cocaine addiction afflicts both sexes, and the sexes can differ in their response to cocaine.We determined how d-amphetamine maintenance therapy during cocaine self-administration influences cocaine use in female rats.In experiment 1, two groups of female rats received 14 intermittent access (IntA) cocaine self-administration sessions. One group received concomitant d-amphetamine maintenance treatment (COC + A rats; 5 mg/kg/day, via minipump), the other group did not (COC rats). After discontinuing d-amphetamine treatment, we measured responding for cocaine under a progressive ratio schedule, responding under extinction, and cocaine-primed reinstatement of drug-seeking. In experiment 2, we assessed the effects of d-amphetamine maintenance on these measures in already IntA cocaine-experienced rats. Thus, rats first received 14 IntA cocaine self-administration sessions without d-amphetamine. They then received 14 more IntA sessions, now either with (COC/COC + A rats) or without (COC/COC rats) concomitant d-amphetamine treatment.In both experiments, d-amphetamine treatment did not significantly influence ongoing cocaine self-administration behaviour. After d-amphetamine treatment cessation, cocaine-primed reinstatement of cocaine-seeking was also unchanged. However, after d-amphetamine treatment cessation, rats responded less for cocaine both under progressive ratio and extinction conditions.D-amphetamine treatment can both prevent and reverse increases in the motivation to take and seek cocaine in female animals." @default.
• W4308766045 created "2022-11-15" @default.
• W4308766045 creator A5054815552 @default.
• W4308766045 creator A5074305496 @default.
• W4308766045 creator A5007219466 @default.
• W4308766045 date "2022-11-11" @default.
• W4308766045 modified "2023-10-14" @default.
• W4308766045 title "D-amphetamine maintenance therapy reduces cocaine use in female rats" @default.
• W4308766045 cites W1823260965 @default.
• W4308766045 cites W1967705120 @default.
• W4308766045 cites W1968515014 @default.
• W4308766045 cites W1968709102 @default.
• W4308766045 cites W1969003613 @default.
• W4308766045 cites W1973003238 @default.
• W4308766045 cites W1976323601 @default.
• W4308766045 cites W1987232587 @default.
• W4308766045 cites W1987710197 @default.
• W4308766045 cites W1988129076 @default.
• W4308766045 cites W2002658604 @default.
• W4308766045 cites W2003836516 @default.
• W4308766045 cites W2015692144 @default.
• W4308766045 cites W2023392538 @default.
• W4308766045 cites W2032755153 @default.
• W4308766045 cites W2032911818 @default.
• W4308766045 cites W2033705393 @default.
• W4308766045 cites W2036502391 @default.
• W4308766045 cites W2037639590 @default.
• W4308766045 cites W2037956616 @default.
• W4308766045 cites W2039273658 @default.
• W4308766045 cites W2043827742 @default.
• W4308766045 cites W2045573797 @default.
• W4308766045 cites W2045729751 @default.
• W4308766045 cites W2048787571 @default.
• W4308766045 cites W2052304909 @default.
• W4308766045 cites W2059543761 @default.
• W4308766045 cites W2066254114 @default.
• W4308766045 cites W2067160513 @default.
• W4308766045 cites W2067626305 @default.
• W4308766045 cites W2070472535 @default.
• W4308766045 cites W2078258865 @default.
• W4308766045 cites W2081308389 @default.
• W4308766045 cites W2083775714 @default.
• W4308766045 cites W2084376094 @default.
• W4308766045 cites W2089885121 @default.
• W4308766045 cites W2090381869 @default.
• W4308766045 cites W2092252344 @default.
• W4308766045 cites W2105908248 @default.
• W4308766045 cites W2134624334 @default.
• W4308766045 cites W2143057278 @default.
• W4308766045 cites W2145051128 @default.
• W4308766045 cites W2169243415 @default.
• W4308766045 cites W2170894460 @default.
• W4308766045 cites W2286968510 @default.
• W4308766045 cites W2305718570 @default.
• W4308766045 cites W2334953621 @default.
• W4308766045 cites W2472306143 @default.
• W4308766045 cites W2475598822 @default.
• W4308766045 cites W2570893979 @default.
• W4308766045 cites W2583072533 @default.
• W4308766045 cites W2610766219 @default.
• W4308766045 cites W2625498710 @default.
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• W4308766045 cites W2769019845 @default.
• W4308766045 cites W2770119180 @default.
• W4308766045 cites W2809405730 @default.
• W4308766045 cites W2898390256 @default.
• W4308766045 cites W2911284908 @default.
• W4308766045 cites W2914795696 @default.
• W4308766045 cites W2919342288 @default.
• W4308766045 cites W2946169416 @default.
• W4308766045 cites W2950487189 @default.
• W4308766045 cites W2952239291 @default.
• W4308766045 cites W2955514859 @default.
• W4308766045 cites W2964512947 @default.
• W4308766045 cites W2981018657 @default.
• W4308766045 cites W3012880995 @default.
• W4308766045 cites W3036689426 @default.
• W4308766045 cites W3038588160 @default.
• W4308766045 cites W3042939327 @default.
• W4308766045 cites W3154990304 @default.
• W4308766045 cites W3204700088 @default.
• W4308766045 cites W4226345903 @default.
• W4308766045 cites W4242056926 @default.
• W4308766045 cites W58014675 @default.
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• W4308766045 doi "https://doi.org/10.1007/s00213-022-06271-w" @default.
• W4308766045 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36357743" @default.
• W4308766045 hasPublicationYear "2022" @default.
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