FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4308771380> ?p ?o ?g. }

• W4308771380 endingPage "533" @default.
• W4308771380 startingPage "520" @default.
• W4308771380 abstract "Haemorrhoidectomy is often complicated by significant post-operative pain, to which spasm of the internal anal sphincter is thought to be a contributing factor. This study appraises the evidence behind interventions aimed at lowering sphincter spasm to relieve post-haemorrhoidectomy pain.A Preferred Reporting Items for Systematic Reviews and Meta-analyses compliant systematic review was conducted. Medline, EMBASE, and CENTRAL databases were systematically searched. All RCTs which compared interventions targeting the internal anal sphincter to relieve pain post excisional haemorrhoidectomy were included. The primary outcome measure was pain on the visual analogue scale.Of the initial 10,221 search results, 39 articles were included in a qualitative synthesis, and 33 studies were included in a meta-analysis. Topical glyceryl trinitrate (GTN) reduced pain on day 7 (7 studies, 485 participants), with a mean difference and 95% confidence interval (MD, 95% CI) of -1.34 (-2.31; -0.37), I2 = 91%. Diltiazem reduced pain on day 3 on the VAS, and the MD was -2.75 (-398; -1.51) shown in five studies (n = 227). Botulinum toxin reduced pain on day 7, in four studies with 178 participants, MD -1.43 (-2.50; -0.35) I2 = 62%. The addition of Lateral Internal Sphincterotomy to haemorrhoidectomy reduced pain on day 2 in three studies with 275 participants, MD of -2.13 (-3.49; -0.77) I2 = 92%. The results were limited by high heterogeneity and risk of bias.Evidence suggests that lateral sphincterotomy, administration of botulinum toxin and the application of topical diltiazem or GTN can reduce post-operative pain after haemorrhoidectomy. Lateral sphincterotomy should not be routinely used due to the risk of incontinence." @default.
• W4308771380 created "2022-11-15" @default.
• W4308771380 creator A5014497774 @default.
• W4308771380 creator A5046287455 @default.
• W4308771380 creator A5046913723 @default.
• W4308771380 creator A5056672598 @default.
• W4308771380 creator A5061348179 @default.
• W4308771380 creator A5085129297 @default.
• W4308771380 date "2022-11-10" @default.
• W4308771380 modified "2023-10-11" @default.
• W4308771380 title "Can Targeting Sphincter Spasm Reduce Post-Haemorrhoidectomy Pain? A Systematic Review and Meta-Analysis" @default.
• W4308771380 cites W1247968195 @default.
• W4308771380 cites W1534181333 @default.
• W4308771380 cites W1929397655 @default.
• W4308771380 cites W1968860678 @default.
• W4308771380 cites W1975682986 @default.
• W4308771380 cites W1980072919 @default.
• W4308771380 cites W1987048715 @default.
• W4308771380 cites W1990825288 @default.
• W4308771380 cites W1992534696 @default.
• W4308771380 cites W2006596495 @default.
• W4308771380 cites W2006734573 @default.
• W4308771380 cites W2011558100 @default.
• W4308771380 cites W2021192980 @default.
• W4308771380 cites W2028017208 @default.
• W4308771380 cites W2030002156 @default.
• W4308771380 cites W2042777534 @default.
• W4308771380 cites W2062419699 @default.
• W4308771380 cites W2062506909 @default.
• W4308771380 cites W2067738952 @default.
• W4308771380 cites W2068797192 @default.
• W4308771380 cites W2077238270 @default.
• W4308771380 cites W2099124163 @default.
• W4308771380 cites W2105771858 @default.
• W4308771380 cites W2109319558 @default.
• W4308771380 cites W2116870679 @default.
• W4308771380 cites W2124110674 @default.
• W4308771380 cites W2297991243 @default.
• W4308771380 cites W2314677945 @default.
• W4308771380 cites W2329366302 @default.
• W4308771380 cites W2337196369 @default.
• W4308771380 cites W2407085153 @default.
• W4308771380 cites W2539312489 @default.
• W4308771380 cites W2911324847 @default.
• W4308771380 cites W2970684805 @default.
• W4308771380 cites W2993120691 @default.
• W4308771380 cites W3026877246 @default.
• W4308771380 cites W3040691717 @default.
• W4308771380 cites W3049163090 @default.
• W4308771380 cites W3096362701 @default.
• W4308771380 cites W3146142859 @default.
• W4308771380 cites W3149758078 @default.
• W4308771380 cites W3169104624 @default.
• W4308771380 cites W3196910410 @default.
• W4308771380 cites W3202499328 @default.
• W4308771380 cites W3207219176 @default.
• W4308771380 cites W4206204274 @default.
• W4308771380 cites W4206239788 @default.
• W4308771380 cites W4226230303 @default.
• W4308771380 cites W4285719527 @default.
• W4308771380 cites W542164 @default.
• W4308771380 cites W6836849 @default.
• W4308771380 doi "https://doi.org/10.1007/s00268-022-06807-3" @default.
• W4308771380 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36357803" @default.
• W4308771380 hasPublicationYear "2022" @default.
• W4308771380 type Work @default.
• W4308771380 citedByCount "0" @default.
• W4308771380 crossrefType "journal-article" @default.
• W4308771380 hasAuthorship W4308771380A5014497774 @default.
• W4308771380 hasAuthorship W4308771380A5046287455 @default.
• W4308771380 hasAuthorship W4308771380A5046913723 @default.
• W4308771380 hasAuthorship W4308771380A5056672598 @default.
• W4308771380 hasAuthorship W4308771380A5061348179 @default.
• W4308771380 hasAuthorship W4308771380A5085129297 @default.
• W4308771380 hasBestOaLocation W43087713801 @default.
• W4308771380 hasConcept C118552586 @default.
• W4308771380 hasConcept C126322002 @default.
• W4308771380 hasConcept C141071460 @default.
• W4308771380 hasConcept C14184104 @default.
• W4308771380 hasConcept C17744445 @default.
• W4308771380 hasConcept C189708586 @default.
• W4308771380 hasConcept C199539241 @default.
• W4308771380 hasConcept C27415008 @default.
• W4308771380 hasConcept C2777478456 @default.
• W4308771380 hasConcept C2779473830 @default.
• W4308771380 hasConcept C2780035688 @default.
• W4308771380 hasConcept C2781074409 @default.
• W4308771380 hasConcept C2781102422 @default.
• W4308771380 hasConcept C42219234 @default.
• W4308771380 hasConcept C44249647 @default.
• W4308771380 hasConcept C71924100 @default.
• W4308771380 hasConcept C95190672 @default.
• W4308771380 hasConceptScore W4308771380C118552586 @default.
• W4308771380 hasConceptScore W4308771380C126322002 @default.
• W4308771380 hasConceptScore W4308771380C141071460 @default.
• W4308771380 hasConceptScore W4308771380C14184104 @default.
• W4308771380 hasConceptScore W4308771380C17744445 @default.
• W4308771380 hasConceptScore W4308771380C189708586 @default.

• next