Matches in SemOpenAlex for { <https://semopenalex.org/work/W4308773062> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W4308773062 endingPage "15929" @default.
- W4308773062 startingPage "15925" @default.
- W4308773062 abstract "Point-of-care devices offering quantitative results with simple steps would allow great useability for untrained end-users. Here, we report a ready-to-use chemosensor integrating automatic sample metering, on-chip reaction, gravitational–magnetic separation, and a distance-based readout for visual quantification of multiple heavy metal ions. Deoxyribozymes (DNAzymes), probe-modified magnetic microparticles (MMPs), and polystyrene microparticles (PMPs) are preloaded into a microfluidic chip and freeze-dried. After the water sample is collected with automatic volume metering, the particles are resuspended, and the MMPs and PMPs hybridize with DNAzyme at its two termini, forming the “MMPs-DNAzyme-PMPs” structure. When target metal ions are present, the DNAzymes are cleaved, yielding an increased number of free PMPs. All on-chip reactions are controlled by stopping the liquid flow at capillary valves and bursting it with hand-controlled tilting. Using the chip with a gravitational–magnetic separator, the free PMPs are separated from “MMPs-DNAzyme-PMPs” and accumulate into the trapping channel with a nozzle, forming a visual bar with growing distances proportional to the concentration of target metal ions. The achieved limit of detection (LOD) values for Cu2+ (103.1 nM), Pb2+ (69.5 nM), and Ag+ (793.6 nM) are below the maximum contamination levels. High selectivity of 100-fold, 200-fold, and 20-fold against interference is obtained. Moreover, by integrating three identical channels in parallel, simultaneous detection of the above-mentioned heavy metal ions in fresh and tap water samples is also achieved with high accuracy. Together, this fully integrated and easily operated platform embodies excellent potential for rapid, on-site sensing by unskilled users." @default.
- W4308773062 created "2022-11-15" @default.
- W4308773062 creator A5016814819 @default.
- W4308773062 creator A5020484864 @default.
- W4308773062 creator A5026969046 @default.
- W4308773062 creator A5052510573 @default.
- W4308773062 creator A5079489769 @default.
- W4308773062 date "2022-11-10" @default.
- W4308773062 modified "2023-09-24" @default.
- W4308773062 title "A Fully Integrated, Ready-to-Use Distance-Based Chemosensor for Visual Quantification of Multiple Heavy Metal Ions" @default.
- W4308773062 cites W1862108443 @default.
- W4308773062 cites W2287718491 @default.
- W4308773062 cites W2325156375 @default.
- W4308773062 cites W2334049801 @default.
- W4308773062 cites W2795980196 @default.
- W4308773062 cites W2810085226 @default.
- W4308773062 cites W2900125792 @default.
- W4308773062 cites W2947405463 @default.
- W4308773062 cites W2993431405 @default.
- W4308773062 cites W2999536926 @default.
- W4308773062 cites W3043768504 @default.
- W4308773062 cites W3137169288 @default.
- W4308773062 cites W3157840142 @default.
- W4308773062 cites W3179608253 @default.
- W4308773062 doi "https://doi.org/10.1021/acs.analchem.2c04712" @default.
- W4308773062 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36356226" @default.
- W4308773062 hasPublicationYear "2022" @default.
- W4308773062 type Work @default.
- W4308773062 citedByCount "5" @default.
- W4308773062 countsByYear W43087730622023 @default.
- W4308773062 crossrefType "journal-article" @default.
- W4308773062 hasAuthorship W4308773062A5016814819 @default.
- W4308773062 hasAuthorship W4308773062A5020484864 @default.
- W4308773062 hasAuthorship W4308773062A5026969046 @default.
- W4308773062 hasAuthorship W4308773062A5052510573 @default.
- W4308773062 hasAuthorship W4308773062A5079489769 @default.
- W4308773062 hasBestOaLocation W43087730621 @default.
- W4308773062 hasConcept C10390740 @default.
- W4308773062 hasConcept C113196181 @default.
- W4308773062 hasConcept C119128265 @default.
- W4308773062 hasConcept C121332964 @default.
- W4308773062 hasConcept C171250308 @default.
- W4308773062 hasConcept C178790620 @default.
- W4308773062 hasConcept C185004128 @default.
- W4308773062 hasConcept C185592680 @default.
- W4308773062 hasConcept C192562407 @default.
- W4308773062 hasConcept C199164860 @default.
- W4308773062 hasConcept C43617362 @default.
- W4308773062 hasConcept C544153396 @default.
- W4308773062 hasConcept C84211826 @default.
- W4308773062 hasConcept C8673954 @default.
- W4308773062 hasConcept C97355855 @default.
- W4308773062 hasConceptScore W4308773062C10390740 @default.
- W4308773062 hasConceptScore W4308773062C113196181 @default.
- W4308773062 hasConceptScore W4308773062C119128265 @default.
- W4308773062 hasConceptScore W4308773062C121332964 @default.
- W4308773062 hasConceptScore W4308773062C171250308 @default.
- W4308773062 hasConceptScore W4308773062C178790620 @default.
- W4308773062 hasConceptScore W4308773062C185004128 @default.
- W4308773062 hasConceptScore W4308773062C185592680 @default.
- W4308773062 hasConceptScore W4308773062C192562407 @default.
- W4308773062 hasConceptScore W4308773062C199164860 @default.
- W4308773062 hasConceptScore W4308773062C43617362 @default.
- W4308773062 hasConceptScore W4308773062C544153396 @default.
- W4308773062 hasConceptScore W4308773062C84211826 @default.
- W4308773062 hasConceptScore W4308773062C8673954 @default.
- W4308773062 hasConceptScore W4308773062C97355855 @default.
- W4308773062 hasIssue "46" @default.
- W4308773062 hasLocation W43087730621 @default.
- W4308773062 hasLocation W43087730622 @default.
- W4308773062 hasOpenAccess W4308773062 @default.
- W4308773062 hasPrimaryLocation W43087730621 @default.
- W4308773062 hasRelatedWork W2120891252 @default.
- W4308773062 hasRelatedWork W2137297405 @default.
- W4308773062 hasRelatedWork W2154588018 @default.
- W4308773062 hasRelatedWork W2159789625 @default.
- W4308773062 hasRelatedWork W2363060927 @default.
- W4308773062 hasRelatedWork W2972588116 @default.
- W4308773062 hasRelatedWork W3143635752 @default.
- W4308773062 hasRelatedWork W3215778902 @default.
- W4308773062 hasRelatedWork W4286773617 @default.
- W4308773062 hasRelatedWork W4292466628 @default.
- W4308773062 hasVolume "94" @default.
- W4308773062 isParatext "false" @default.
- W4308773062 isRetracted "false" @default.
- W4308773062 workType "article" @default.