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• W4308799139 abstract "Context: CC was widely used for ovulation induction in women with anovulatory infertility; aromatase inhibitors like letrozole can be used for better pregnancy outcomes in these patients. Aims: To compare the effect of CC and letrozole on ovulation induction in females with primary infertility due to anovulation. Settings and Design: An Observational study at Tertiary Health care centre, at Department of Obstetrics and Gynaecology, AVBRH, DMIMS, Sawangi (Meghe), Wardha. Methods and Material: 120 patients were divided into two equal groups. Both CC and Letrozole were given from Day 3 to Day 7 of menstrual cycle. Folliculometry was done from Day 8 on alternate days till Day 16 or till atleast one follicle reaches ≥ 18mm. Inj hCG 10,000 was given. The treatment was given for three cycles in both the groups. Main outcome measures: Ovulation Rate, Pregnancy rate, Endometrial thickness. Statistical analysis used: SPSS 24.0 version and GraphPad Prism 7.0 version. Results: The mean age, Body Mass Index (BMI), duration of infertility in both CC and Letrozole groups were similar. Ovulation rate was 72.33% in letrozole group and 63% in CC, which was not statistically signicant (p=0.17). There was statistically signicant difference between Endometrial thickness (CC 8.29±0.73, Let 9.45±0.60, p<0.05, S).Monofollicular rate was more in Let than CC and this being statistically signicant (Let-76.74%, CC- 51.24%, p<0.05,S). Let group had pregnancy rate as 43.33% as compared to 18.33% in CC group and this statistically signicant (p<0.05,S). Conclusions: Present study showed that Letrozole had better pregnancy rates than CC. Letrozole can be used as a choice of drug for ovulation induction in females with infertility due to anovulation." @default.
• W4308799139 created "2022-11-15" @default.
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• W4308799139 date "2022-10-15" @default.
• W4308799139 modified "2023-10-16" @default.
• W4308799139 title "COMPARING LETROZOLE AND CLOMIPHENE CITRATE FOR OVULATION INDUCTION IN FEMALES WITH PRIMARY INFERTILITY DUE TO ANOVULATION." @default.
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• W4308799139 doi "https://doi.org/10.36106/gjra/1208563" @default.
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