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• W4308907425 abstract "Viral gene transfer, known as transduction, is a powerful research tool for studying the biology of chondrocytes in novel ways and also a technology enabling the use of gene therapy for regenerating cartilage and treating diseases that affect cartilage, such as osteoarthritis. Adenovirus, retrovirus, lentivirus, and adeno-associated virus (AAV) are most commonly used to transduce chondrocytes. Although AAV is able to transduce chondrocytes in situ by intra-articular injection, chondrocytes are most commonly transduced in monolayer culture using the four vectors mentioned above. Protocols for achieving this are described, along with a discussion of the variables that can influence transduction efficiency." @default.
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• W4308907425 date "2022-11-11" @default.
• W4308907425 modified "2023-09-27" @default.
• W4308907425 title "Viral Gene Delivery in Chondrocytes" @default.
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• W4308907425 doi "https://doi.org/10.1007/978-1-0716-2839-3_20" @default.
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