FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4308951085> ?p ?o ?g. }

• W4308951085 endingPage "106979" @default.
• W4308951085 startingPage "106979" @default.
• W4308951085 abstract "Dear Editor, We wish to thank Drs Luo, Gu and Xiang for their comments and feedback mentioned in “A commentary on “Personalized pre-habilitation reduces anastomotic complications compared to up front surgery before ileocolic resection in high-risk patients with Crohn's disease: A single center retrospective study” (Int J Surg 2022; 106:106887) and we would like to take the opportunity to answer to the stated queries. Dr Luo et al. mentioned that our decision to stop “immunosuppressive treatments in PP, which has no theoretical basis and evidence to support”. The just released review focusing on pre-operative management [1] also states that IS treatments “can be continued during the peri-operative period”. We agree that those treatments do not seem to increase post-operative complications. However, one could argue that if stopping other IS treatments (excepting corticosteroids) is not mandatory, it is not recommended as well. In our daily practice, we stop the immunosuppressive (IS) treatments in PP systematically based on the surgical treatment ECCO guidelines [2] that gave 2 statements regarding preoperative medications: “i) Preoperative corticosteroid use is associated with increased risk of postoperative complications; ii) Cessation of preoperative treatment with anti-TNF therapy, vedolizumab, or ustekinumab prior to surgery is not mandatory.” Also, we stop it because, in our institution, we consider that the onset of intra-abdominal complications is a sign of treatment inefficiency and continuing it does not seem relevant. Dr Luo et al. stated that patient's group repartition was not balanced. This monocentric retrospective study was a report of a real-life experiment over a decade in France and we came across some pitfalls highlighted in our discussion “Firstly, the particularity of this study is that our 2 groups are not strictly comparable and that a patient selection in the realization of a PP was clearly done”. Authors also stated that and that demographics and especially the sex-ratio was “not consistent with that of the real world “. However, If the sex ratio mentioned by Park SH et al. [3] is representative of East Asian countries, the epidemiology differs in Western countries. Several studies have confirmed this difference in sex ratio in the past decade [4–6]. Moreover, as reported very recently by Arkenbosch et al. [7], among the 213 CD Dutch patients included, 65% were female, concordant with our published one (65.6%). Therefore, this highlights the need of being extremely cautious on the will of generalizing results and the necessity of interpreting study results according to its context. Thirdly, we would like to clarify our methodology on our prehabilitation program. The Personalized-Prehabilitation program, as reported, is, by definition, a concept that overlaps pre-operative nutrition, treatment adjustments, and control of intra-abdominal sepsis. Enhanced recovery programs, and in particular the Enhanced Recovery After Surgery program, have been designed the same way and nobody argue on its clinical benefit [8]. In recent ECCO topical review entitled “Roadmap to optimal peri-operative care in IBD” [1], Sebastian et al. also discusses the implementation of psychological and physical rehabilitation in such a program. In everyday practice, each patient presents different clinical history, so we have tailored our pre-operative strategy according to their own risk factors. Thus, it is true that this multifactorial program increased the heterogeneity intra and inter-group, but we mentioned it in the discussion as a shortcoming of our study: “Firstly, the particularity of this study is that our 2 groups are not strictly comparable […]”; “Thirdly the prehabilitation protocol is a tailored protocol”. In our study, we chose 3 risk factors: hypoalbuminemia, corticosteroids administration, and presence of fistula or abscess. For these criteria, only hypoalbuminemia could increase “spontaneously” because of patient nutrition or some other personal behavior. But for the others, it is hard to believe that they might vanish without any medical action or prescription. In the article cited by Dr Luo et al. [9], authors discussed the putative benefit of Omega3 supplementation in the general population. So, albumin increase cannot be considered as spontaneous if there is supplementation of any kind. Then, populations of both studies are not comparable due to Crohn's disease characteristics (imbalance inflammation state, malabsorption …). Moreover, in the cited article, we did not find any subgroup analysis on IBD patients. Therefore, it seems to us inappropriate to generalize those results to our study population. Fourthly, we also agree with Dr Luo et al. that emergency surgery by itself is considered as a “risk factor”. Indeed, it is well described that patient undergoing nonelective surgery for Crohn's disease have poorer outcomes [10,11] However, as we mentioned in our discussion “clinical situations justifying emergency surgical procedure in IBD patients are in fact quite sparse (general peritonitis and/or bowel ischemia) thanks to the improvement of conservative management and in particular percutaneous guided drainage.” Indeed, our study included patients over 10 years and, as conservative management improved over this period of time, we tried to rehabilitate as much as possible our patients to avoid emergency surgery which is more complex and risky [12]. Therefore, we did not include patient with emergency surgery for the following reasons: i) emergencies indications were parsimonious; ii) a split stoma was mostly performed in case of emergency surgery which was defined as an exclusion criterion in our study design. Finally, to clarify our preoperative workup, we did a CT-scan or Entero-MRI for all patient prior to surgery to assess the severity of the disease, and to diagnose putative associated complications (like abscess, fistula or, multiple stenosis). For patients that have been prepared for fistula/abscess criteria, we also performed a CT scan before AND after prehabilitation program to evaluate treatment efficiency. Ethical approval None. Sources of funding for your research None. Author contribution All authors declare to have sufficiently participated in the work to take public responsibility for appropriate portions of the content, as defined in the guidelines of the International Committee of Medical Journal Editors (ICMJE). Authors' contributions: CF, T.B., and R.S. were responsible for study concept and design, contributed to acquisition and interpretation of data, performed drafting of the manuscript and contributed to critical revision. All authors have viewed and approved the final version of the manuscript and agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are. Research registration unique identifying number (UIN) None. Guarantor Dr Francoise Guillon Digestive and Mini-invasive Surgery unit. Department of digestive surgery and transplantation. St Eloi Hospital, University of Montpellier. 80 avenue Augustin Fliche, 34295, Montpellier, France. Tel: +33467337072. Mail: [email protected]. Provenance and peer review Correspondence, internally reviewed. Declaration of competing interest All authors declare no competing interests. Charlotte Ferrandis Regis Souche Thomas Bardol Department of Digestive Surgery (IBD Surgical Unit), University Hospital Center, Montpellier-Nimes University, 641 Avenue du Doyen Gaston Giraud, 34090, Montpellier, France E-mail addresses:[email protected]" @default.
• W4308951085 created "2022-11-20" @default.
• W4308951085 creator A5013624146 @default.
• W4308951085 creator A5065954254 @default.
• W4308951085 creator A5065983164 @default.
• W4308951085 date "2022-12-01" @default.
• W4308951085 modified "2023-09-27" @default.
• W4308951085 title "Reply to “A Commentary on “Personalized pre-habilitation reduces anastomotic complications compared to up front surgery before ileocolic resection in high-risk patients with Crohn's disease: A single center retrospective study” [Int. J. Surg. 105 (2022) 106815]”" @default.
• W4308951085 cites W2083533774 @default.
• W4308951085 cites W2573978544 @default.
• W4308951085 cites W2767783660 @default.
• W4308951085 cites W2774317166 @default.
• W4308951085 cites W2900811409 @default.
• W4308951085 cites W2939262809 @default.
• W4308951085 cites W2982576455 @default.
• W4308951085 cites W2984128211 @default.
• W4308951085 cites W4290673847 @default.
• W4308951085 cites W4294542936 @default.
• W4308951085 doi "https://doi.org/10.1016/j.ijsu.2022.106979" @default.
• W4308951085 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36396120" @default.
• W4308951085 hasPublicationYear "2022" @default.
• W4308951085 type Work @default.
• W4308951085 citedByCount "0" @default.
• W4308951085 crossrefType "journal-article" @default.
• W4308951085 hasAuthorship W4308951085A5013624146 @default.
• W4308951085 hasAuthorship W4308951085A5065954254 @default.
• W4308951085 hasAuthorship W4308951085A5065983164 @default.
• W4308951085 hasBestOaLocation W43089510851 @default.
• W4308951085 hasConcept C126322002 @default.
• W4308951085 hasConcept C138885662 @default.
• W4308951085 hasConcept C141071460 @default.
• W4308951085 hasConcept C15708023 @default.
• W4308951085 hasConcept C167135981 @default.
• W4308951085 hasConcept C2779134260 @default.
• W4308951085 hasConcept C2779280984 @default.
• W4308951085 hasConcept C2780073493 @default.
• W4308951085 hasConcept C2908837262 @default.
• W4308951085 hasConcept C61434518 @default.
• W4308951085 hasConcept C71924100 @default.
• W4308951085 hasConcept C8443397 @default.
• W4308951085 hasConceptScore W4308951085C126322002 @default.
• W4308951085 hasConceptScore W4308951085C138885662 @default.
• W4308951085 hasConceptScore W4308951085C141071460 @default.
• W4308951085 hasConceptScore W4308951085C15708023 @default.
• W4308951085 hasConceptScore W4308951085C167135981 @default.
• W4308951085 hasConceptScore W4308951085C2779134260 @default.
• W4308951085 hasConceptScore W4308951085C2779280984 @default.
• W4308951085 hasConceptScore W4308951085C2780073493 @default.
• W4308951085 hasConceptScore W4308951085C2908837262 @default.
• W4308951085 hasConceptScore W4308951085C61434518 @default.
• W4308951085 hasConceptScore W4308951085C71924100 @default.
• W4308951085 hasConceptScore W4308951085C8443397 @default.
• W4308951085 hasLocation W43089510851 @default.
• W4308951085 hasLocation W43089510852 @default.
• W4308951085 hasOpenAccess W4308951085 @default.
• W4308951085 hasPrimaryLocation W43089510851 @default.
• W4308951085 hasRelatedWork W1971326018 @default.
• W4308951085 hasRelatedWork W2018266824 @default.
• W4308951085 hasRelatedWork W2076842282 @default.
• W4308951085 hasRelatedWork W2147181164 @default.
• W4308951085 hasRelatedWork W2378358762 @default.
• W4308951085 hasRelatedWork W3139267926 @default.
• W4308951085 hasRelatedWork W4214517713 @default.
• W4308951085 hasRelatedWork W4305082178 @default.
• W4308951085 hasRelatedWork W4319440053 @default.
• W4308951085 hasRelatedWork W4319982561 @default.
• W4308951085 hasVolume "108" @default.
• W4308951085 isParatext "false" @default.
• W4308951085 isRetracted "false" @default.
• W4308951085 workType "article" @default.